Atomic force microscopy for single molecule characterisation of protein aggregation

por Ruggeri, Francesco Simone, Šneideris, Tomas, Vendruscolo, Michele, Knowles, Tuomas P.J.
Publicado 2019

Easyworm: an open-source software tool to determine the mechanical properties of worm-like chains

por Lamour, Guillaume, Kirkegaard, Julius B, Li, Hongbin, Knowles, Tuomas PJ, Gsponer, Jörg
Publicado 2014

Protocol to determine antibody affinity and concentration in complex solutions using microfluidic antibody affinity profiling

por Emmenegger, Marc, Worth, Roland, Fiedler, Sebastian, Devenish, Sean R.A., Knowles, Tuomas P.J., Aguzzi, Adriano
Publicado 2023

Automated Ex Situ Assays of Amyloid Formation on a Microfluidic Platform

por Saar, Kadi-Liis, Yates, Emma V., Müller, Thomas, Saunier, Séverine, Dobson, Christopher M., Knowles, Tuomas P.J.
Publicado 2016

Aging can transform single-component protein condensates into multiphase architectures

por Garaizar, Adiran, Espinosa, Jorge R., Joseph, Jerelle A., Krainer, Georg, Shen, Yi, Knowles, Tuomas P.J., Collepardo-Guevara, Rosana
Publicado 2022

A mechanistic model of tau amyloid aggregation based on direct observation of oligomers

por Shammas, Sarah L., Garcia, Gonzalo A., Kumar, Satish, Kjaergaard, Magnus, Horrocks, Mathew H., Shivji, Nadia, Mandelkow, Eva, Knowles, Tuomas P.J., Mandelkow, Eckhard, Klenerman, David
Publicado 2015

The Interaction of αB-Crystallin with Mature α-Synuclein Amyloid Fibrils Inhibits Their Elongation

por Waudby, Christopher A., Knowles, Tuomas P.J., Devlin, Glyn L., Skepper, Jeremy N., Ecroyd, Heath, Carver, John A., Welland, Mark E., Christodoulou, John, Dobson, Christopher M., Meehan, Sarah
Publicado 2010

Multidimensional Protein Solubility Optimization with an Ultrahigh-Throughput Microfluidic Platform

por Erkamp, Nadia A., Oeller, Marc, Sneideris, Tomas, Ausserwoger, Hannes, Levin, Aviad, Welsh, Timothy J., Qi, Runzhang, Qian, Daoyuan, Lorenzen, Nikolai, Zhu, Hongjia, Sormanni, Pietro, Vendruscolo, Michele, Knowles, Tuomas P.J.
Publicado 2023

Characterization of full-length p53 aggregates and their kinetics of formation

por Julian, Linda, Sang, Jason C., Wu, Yunzhao, Meisl, Georg, Brelstaff, Jack H., Miller, Alyssa, Cheetham, Matthew R., Vendruscolo, Michele, Knowles, Tuomas P.J., Ruggeri, Francesco Simone, Bryant, Clare, Ros, Susana, Brindle, Kevin M., Klenerman, David
Publicado 2022

Liquid–liquid phase separation underpins the formation of replication factories in rotaviruses

por Geiger, Florian, Acker, Julia, Papa, Guido, Wang, Xinyu, Arter, William E, Saar, Kadi L, Erkamp, Nadia A, Qi, Runzhang, Bravo, Jack PK, Strauss, Sebastian, Krainer, Georg, Burrone, Oscar R, Jungmann, Ralf, Knowles, Tuomas PJ, Engelke, Hanna, Borodavka, Alexander
Publicado 2021

Direct Observation of the Interconversion of Normal and Toxic Forms of α-Synuclein

por Cremades, Nunilo, Cohen, Samuel I.A., Deas, Emma, Abramov, Andrey Y., Chen, Allen Y., Orte, Angel, Sandal, Massimo, Clarke, Richard W., Dunne, Paul, Aprile, Francesco A., Bertoncini, Carlos W., Wood, Nicholas W., Knowles, Tuomas P.J., Dobson, Christopher M., Klenerman, David
Publicado 2012

Microfluidic characterisation reveals broad range of SARS-CoV-2 antibody affinity in human plasma

por Schneider, Matthias M, Emmenegger, Marc, Xu, Catherine K, Condado Morales, Itzel, Meisl, Georg, Turelli, Priscilla, Zografou, Chryssa, Zimmermann, Manuela R, Frey, Beat M, Fiedler, Sebastian, Denninger, Viola, Jacquat, Raphaël PB, Madrigal, Lidia, Ilsley, Alison, Kosmoliaptsis, Vasilis, Fiegler, Heike, Trono, Didier, Knowles, Tuomas PJ, Aguzzi, Adriano
Publicado 2021

Both COVID-19 infection and vaccination induce high-affinity cross-clade responses to SARS-CoV-2 variants

por Emmenegger, Marc, Fiedler, Sebastian, Brugger, Silvio D., Devenish, Sean R.A., Morgunov, Alexey S., Ilsley, Alison, Ricci, Francesco, Malik, Anisa Y., Scheier, Thomas, Batkitar, Leyla, Madrigal, Lidia, Rossi, Marco, Meisl, Georg, Lynn, Andrew K., Saleh, Lanja, von Eckardstein, Arnold, Knowles, Tuomas P.J., Aguzzi, Adriano
Publicado 2022

RNA Granules Hitchhike on Lysosomes for Long-Distance Transport, Using Annexin A11 as a Molecular Tether

por Liao, Ya-Cheng, Fernandopulle, Michael S., Wang, Guozhen, Choi, Heejun, Hao, Ling, Drerup, Catherine M., Patel, Rajan, Qamar, Seema, Nixon-Abell, Jonathon, Shen, Yi, Meadows, William, Vendruscolo, Michele, Knowles, Tuomas P.J., Nelson, Matthew, Czekalska, Magdalena A., Musteikyte, Greta, Gachechiladze, Mariam A., Stephens, Christina A., Pasolli, H. Amalia, Forrest, Lucy R., St George-Hyslop, Peter, Lippincott-Schwartz, Jennifer, Ward, Michael E.
Publicado 2019

Continuous population-level monitoring of SARS-CoV-2 seroprevalence in a large European metropolitan region

por Emmenegger, Marc, De Cecco, Elena, Lamparter, David, Jacquat, Raphaël P.B., Riou, Julien, Menges, Dominik, Ballouz, Tala, Ebner, Daniel, Schneider, Matthias M., Morales, Itzel Condado, Doğançay, Berre, Guo, Jingjing, Wiedmer, Anne, Domange, Julie, Imeri, Marigona, Moos, Rita, Zografou, Chryssa, Batkitar, Leyla, Madrigal, Lidia, Schneider, Dezirae, Trevisan, Chiara, Gonzalez-Guerra, Andres, Carrella, Alessandra, Dubach, Irina L., Xu, Catherine K., Meisl, Georg, Kosmoliaptsis, Vasilis, Malinauskas, Tomas, Burgess-Brown, Nicola, Owens, Ray, Hatch, Stephanie, Mongkolsapaya, Juthathip, Screaton, Gavin R., Schubert, Katharina, Huck, John D., Liu, Feimei, Pojer, Florence, Lau, Kelvin, Hacker, David, Probst-Müller, Elsbeth, Cervia, Carlo, Nilsson, Jakob, Boyman, Onur, Saleh, Lanja, Spanaus, Katharina, von Eckardstein, Arnold, Schaer, Dominik J., Ban, Nenad, Tsai, Ching-Ju, Marino, Jacopo, Schertler, Gebhard F.X., Ebert, Nadine, Thiel, Volker, Gottschalk, Jochen, Frey, Beat M., Reimann, Regina R., Hornemann, Simone, Ring, Aaron M., Knowles, Tuomas P.J., Puhan, Milo A., Althaus, Christian L., Xenarios, Ioannis, Stuart, David I., Aguzzi, Adriano
Publicado 2023