Rhinitis, sinusitis and ocular disease – 2098. Exhaled NO may predict development of allergic rhinitis in children with asthma

por Rha, Yeong Ho, Ko, Han Seok
Publicado 2013

Levodopa-Induced Dyskinesia in Parkinson’s Disease: Pathogenesis and Emerging Treatment Strategies

por Kwon, Destany K., Kwatra, Mohit, Wang, Jing, Ko, Han Seok
Publicado 2022

A novel extended form of alpha-synuclein 3′UTR in the human brain

por Je, Goun, Guhathakurta, Subhrangshu, Yun, Seung Pil, Ko, Han Seok, Kim, Yoon-Seong
Publicado 2018

The c-Abl inhibitor, Nilotinib, protects dopaminergic neurons in a preclinical animal model of Parkinson's disease

por Karuppagounder, Senthilkumar S., Brahmachari, Saurav, Lee, Yunjong, Dawson, Valina L., Dawson, Ted M., Ko, Han Seok
Publicado 2014

c-Abl and Parkinson’s Disease: Mechanisms and Therapeutic Potential

por Brahmachari, Saurav, Karuppagounder, Senthilkumar S., Ge, Preston, Lee, Saebom, Dawson, Valina L., Dawson, Ted M., Ko, Han Seok
Publicado 2017

D409H GBA1 mutation accelerates the progression of pathology in A53T α-synuclein transgenic mouse model

por Kim, Donghoon, Hwang, Heehong, Choi, Seulah, Kwon, Sang Ho, Lee, Suhyun, Park, Jae Hong, Kim, SangMin, Ko, Han Seok
Publicado 2018

Linking Gba1 E326K mutation to microglia activation and mild age-dependent dopaminergic Neurodegeneration

por Kweon, Sin Ho, Ryu, Hye Guk, Park, Hyeonwoo, Lee, Saebom, Kim, Namshik, Kwon, Seung-Hwan, Ma, Shi-Xun, Kim, Sangjune, Ko, Han Seok
Publicado 2023

Alpha-Synuclein Preformed Fibrils Induce Cellular Senescence in Parkinson’s Disease Models

por Verma, Dinesh Kumar, Seo, Bo Am, Ghosh, Anurupa, Ma, Shi-Xun, Hernandez-Quijada, Karina, Andersen, Julie K., Ko, Han Seok, Kim, Yong-Hwan
Publicado 2021

VPS35 regulates parkin substrate AIMP2 toxicity by facilitating lysosomal clearance of AIMP2

por Yun, Seung Pil, Kim, Hyojung, Ham, Sangwoo, Kwon, Seung-Hwan, Lee, Gum Hwa, Shin, Joo-Ho, Lee, Sang Hun, Ko, Han Seok, Lee, Yunjong
Publicado 2017

c-Abl Regulates the Pathological Deposition of TDP-43 via Tyrosine 43 Phosphorylation

por Lee, Saebom, Ryu, Hye Guk, Kweon, Sin Ho, Kim, Hyerynn, Park, Hyeonwoo, Lee, Kyung-Ha, Jang, Sang-Min, Na, Chan Hyun, Kim, Sangjune, Ko, Han Seok
Publicado 2022

Lysosomal Enzyme Glucocerebrosidase Protects against Aβ(1-42) Oligomer-Induced Neurotoxicity

por Choi, Seulah, Kim, Donghoon, Kam, Tae-In, Yun, Seungpil, Kim, Sangjune, Park, Hyejin, Hwang, Heehong, Pletnikova, Olga, Troncoso, Juan C., Dawson, Valina L., Dawson, Ted M., Ko, Han Seok
Publicado 2015

Defects in Mitochondrial Biogenesis Drive Mitochondrial Alterations in PARKIN-Deficient Human Dopamine Neurons

por Kumar, Manoj, Acevedo-Cintrón, Jesús, Jhaldiyal, Aanishaa, Wang, Hu, Andrabi, Shaida A., Eacker, Stephen, Karuppagounder, Senthilkumar S., Brahmachari, Saurav, Chen, Rong, Kim, Hyesoo, Ko, Han Seok, Dawson, Valina L., Dawson, Ted M.
Publicado 2020

Sulfhydration mediates neuroprotective actions of parkin

por Vandiver, M. Scott, Paul, Bindu D., Xu, Risheng, Karuppagounder, Senthilkumar, Rao, Feng, Snowman, Adele M., Ko, Han Seok, Lee, Yun Il, Dawson, Valina L., Dawson, Ted M., Sen, Nilkantha, Snyder, Solomon H.
Publicado 2013

Overexpression of Parkinson’s Disease-Associated Mutation LRRK2 G2019S in Mouse Forebrain Induces Behavioral Deficits and α-Synuclein Pathology

por Xiong, Yulan, Neifert, Stewart, Karuppagounder, Senthilkumar S., Stankowski, Jeannette N., Lee, Byoung Dae, Grima, Jonathan C., Chen, Guanxing, Ko, Han Seok, Lee, Yunjong, Swing, Debbie, Tessarollo, Lino, Dawson, Ted M., Dawson, Valina L.
Publicado 2017

Mitochondrial dysfunction and mitophagy defect triggered by heterozygous GBA mutations

por Li, Hongyu, Ham, Ahrom, Ma, Thong Chi, Kuo, Sheng-Han, Kanter, Ellen, Kim, Donghoon, Ko, Han Seok, Quan, Yi, Sardi, Sergio Pablo, Li, Aiqun, Arancio, Ottavio, Kang, Un Jung, Sulzer, David, Tang, Guomei
Publicado 2018

Inhibitors of Leucine Rich Repeat Kinase 2 (LRRK2) Protect Against LRRK2-Models of Parkinson’s Disease

por Lee, Byoung Dae, Shin, Joo-Ho, VanKampen, Jackalina, Petrucelli, Leonard, West, Andrew B., Ko, Han Seok, Lee, Yun, Maguire-Zeiss, Kathleen A., Bowers, William J., Federoff, Howard J., Dawson, Valina L., Dawson, Ted M.
Publicado 2010

Parthanatos Mediates AIMP2 Activated Age Dependent Dopaminergic Neuronal Loss

por Lee, Yunjong, Karuppagounder, Senthilkumar S., Shin, Joo-Ho, Lee, Yun-Il, Ko, Han Seok, Swing, Debbie, Jiang, Haisong, Kang, Sung-Ung, Lee, Byoung Dae, Kang, Ho Chul, Kim, Donghoon, Tessarollo, Lino, Dawson, Valina L., Dawson, Ted M.
Publicado 2013

α-Synuclein accumulation and GBA deficiency due to L444P GBA mutation contributes to MPTP-induced parkinsonism

por Yun, Seung Pil, Kim, Donghoon, Kim, Sangjune, Kim, SangMin, Karuppagounder, Senthilkumar S., Kwon, Seung-Hwan, Lee, Saebom, Kam, Tae-In, Lee, Suhyun, Ham, Sangwoo, Park, Jae Hong, Dawson, Valina L., Dawson, Ted M., Lee, Yunjong, Ko, Han Seok
Publicado 2018

Cell-Based Screen Using Amyloid Mimic β23 Expression Identifies Peucedanocoumarin III as a Novel Inhibitor of α-Synuclein and Huntingtin Aggregates

por Ham, Sangwoo, Kim, Hyojung, Hwang, Seojin, Kang, Hyunook, Yun, Seung Pil, Kim, Sangjune, Kim, Donghoon, Kwon, Hyun Sook, Lee, Yun-Song, Cho, MyoungLae, Shin, Heung-Mook, Choi, Heejung, Chung, Ka Young, Ko, Han Seok, Lee, Gum Hwa, Lee, Yunjong
Publicado 2019

The c-Abl inhibitor, Radotinib HCl, is neuroprotective in a preclinical Parkinson’s disease mouse model

por Lee, Saebom, Kim, Sangjune, Park, Yong Joo, Yun, Seung Pil, Kwon, Seung-Hwan, Kim, Donghoon, Kim, Dong Yeon, Shin, Jae Soo, Cho, Dae Jin, Lee, Gong Yeal, Ju, Hyun Soo, Yun, Hyo Jung, Park, Jae Hong, Kim, Wonjoong Richard, Jung, Eun Ah, Lee, Seulki, Ko, Han Seok
Publicado 2018