Hepatocyte-specific IL11 cis-signaling drives lipotoxicity and underlies the transition from NAFLD to NASH

por Dong, Jinrui, Viswanathan, Sivakumar, Adami, Eleonora, Singh, Brijesh K., Chothani, Sonia P., Ng, Benjamin, Lim, Wei Wen, Zhou, Jin, Tripathi, Madhulika, Ko, Nicole S. J., Shekeran, Shamini G., Tan, Jessie, Lim, Sze Yun, Wang, Mao, Lio, Pei Min, Yen, Paul M., Schafer, Sebastian, Cook, Stuart A., Widjaja, Anissa A.
Publicado 2021

Interleukin-11 is important for vascular smooth muscle phenotypic switching and aortic inflammation, fibrosis and remodeling in mouse models

por Lim, Wei-Wen, Corden, Ben, Ng, Benjamin, Vanezis, Konstantinos, D’Agostino, Giuseppe, Widjaja, Anissa A., Song, Wei-Hua, Xie, Chen, Su, Liping, Kwek, Xiu-Yi, Tee, Nicole G. Z., Dong, Jinrui, Ko, Nicole S. J., Wang, Mao, Pua, Chee Jian, Jamal, Muhammad H., Soh, Beeyong, Viswanathan, Sivakumar, Schafer, Sebastian, Cook, Stuart A.
Publicado 2020

Titin truncating variants affect heart function in disease cohorts and the general population

por Schafer, Sebastian, de Marvao, Antonio, Adami, Eleonora, Fiedler, Lorna R, Ng, Benjamin, Khin, Ester, Rackham, Owen J L, van Heesch, Sebastiaan, Pua, Chee J, Kui, Miao, Walsh, Roddy, Tayal, Upasana, Prasad, Sanjay K, Dawes, Timothy J W, Ko, Nicole S J, Sim, David, Chan, Laura L, Chin, Calvin W L, Mazzarotto, Francesco, Barton, Paul J, Kreuchwig, Franziska, de Kleijn, Dominique P V, Totman, Teresa, Biffi, Carlo, Tee, Nicole, Rueckert, Daniel, Schneider, Valentin, Faber, Allison, Regitz-Zagrosek, Vera, Seidman, Jonathan G, Seidman, Christine E, Linke, Wolfgang A, Kovalik, Jean-Paul, O’Regan, Declan Patrick, Ware, James S, Hubner, Norbert, Cook, Stuart A
Publicado 2016