Discovery and Development of Anti-HIV Therapeutic Agents: Progress Towards Improved HIV Medication

por Maeda, Kenji, Das, Debananda, Kobayakawa, Takuya, Tamamura, Hirokazu, Takeuchi, Hiroaki
Publicado 2019

Dimerized fusion inhibitor peptides targeting the HR1–HR2 interaction of SARS-CoV-2

por Tsuji, Kohei, Baffour-Awuah Owusu, Kofi, Miura, Yutaro, Ishii, Takahiro, Shinohara, Kouki, Kobayakawa, Takuya, Emi, Akino, Nakano, Takashi, Suzuki, Youichi, Tamamura, Hirokazu
Publicado 2023

Benzolactam-related compounds promote apoptosis of HIV-infected human cells via protein kinase C–induced HIV latency reversal

por Matsuda, Kouki, Kobayakawa, Takuya, Tsuchiya, Kiyoto, Hattori, Shin-ichiro, Nomura, Wataru, Gatanaga, Hiroyuki, Yoshimura, Kazuhisa, Oka, Shinichi, Endo, Yasuyuki, Tamamura, Hirokazu, Mitsuya, Hiroaki, Maeda, Kenji
Publicado 2019

Small-Molecule Anti-HIV-1 Agents Based on HIV-1 Capsid Proteins

por Kobayakawa, Takuya, Yokoyama, Masaru, Tsuji, Kohei, Fujino, Masayuki, Kurakami, Masaki, Boku, Sayaka, Nakayama, Miyuki, Kaneko, Moemi, Ohashi, Nami, Kotani, Osamu, Murakami, Tsutomu, Sato, Hironori, Tamamura, Hirokazu
Publicado 2021

A Therapeutic Strategy to Combat HIV-1 Latently Infected Cells With a Combination of Latency-Reversing Agents Containing DAG-Lactone PKC Activators

por Matsuda, Kouki, Kobayakawa, Takuya, Kariya, Ryusho, Tsuchiya, Kiyoto, Ryu, Shoraku, Tsuji, Kohei, Ishii, Takahiro, Gatanaga, Hiroyuki, Yoshimura, Kazuhisa, Okada, Seiji, Hamada, Akinobu, Mitsuya, Hiroaki, Tamamura, Hirokazu, Maeda, Kenji
Publicado 2021

Low-molecular-weight anti-HIV-1 agents targeting HIV-1 capsid proteins

por Kobayakawa, Takuya, Yokoyama, Masaru, Tsuji, Kohei, Fujino, Masayuki, Kurakami, Masaki, Onishi, Takato, Boku, Sayaka, Ishii, Takahiro, Miura, Yutaro, Shinohara, Kouki, Kishihara, Yuki, Ohashi, Nami, Kotani, Osamu, Murakami, Tsutomu, Sato, Hironori, Tamamura, Hirokazu
Publicado 2023

Potent and biostable inhibitors of the main protease of SARS-CoV-2

por Tsuji, Kohei, Ishii, Takahiro, Kobayakawa, Takuya, Higashi-Kuwata, Nobuyo, Azuma, Chika, Nakayama, Miyuki, Onishi, Takato, Nakano, Hiroki, Wada, Naoya, Hori, Miki, Shinohara, Kouki, Miura, Yutaro, Kawada, Takuma, Hayashi, Hironori, Hattori, Shin-ichiro, Bulut, Haydar, Das, Debananda, Takamune, Nobutoki, Kishimoto, Naoki, Saruwatari, Junji, Okamura, Tadashi, Nakano, Kenta, Misumi, Shogo, Mitsuya, Hiroaki, Tamamura, Hirokazu
Publicado 2022

Identification of SARS-CoV-2 M(pro) inhibitors containing P1’ 4-fluorobenzothiazole moiety highly active against SARS-CoV-2

por Higashi-Kuwata, Nobuyo, Tsuji, Kohei, Hayashi, Hironori, Bulut, Haydar, Kiso, Maki, Imai, Masaki, Ogata-Aoki, Hiromi, Ishii, Takahiro, Kobayakawa, Takuya, Nakano, Kenta, Takamune, Nobutoki, Kishimoto, Naoki, Hattori, Shin-ichiro, Das, Debananda, Uemura, Yukari, Shimizu, Yosuke, Aoki, Manabu, Hasegawa, Kazuya, Suzuki, Satoshi, Nishiyama, Akie, Saruwatari, Junji, Shimizu, Yukiko, Sukenaga, Yoshikazu, Takamatsu, Yuki, Tsuchiya, Kiyoto, Maeda, Kenji, Yoshimura, Kazuhisa, Iida, Shun, Ozono, Seiya, Suzuki, Tadaki, Okamura, Tadashi, Misumi, Shogo, Kawaoka, Yoshihiro, Tamamura, Hirokazu, Mitsuya, Hiroaki
Publicado 2023