Febuxostat, a Xanthine Oxidoreductase Inhibitor, Decreases NLRP3-dependent Inflammation in Macrophages by Activating the Purine Salvage Pathway and Restoring Cellular Bioenergetics

por Nomura, Johji, Kobayashi, Tsunefumi, So, Alexander, Busso, Nathalie
Publicado 2019

Prophylactic treatment with sulphonated immunoglobulin G attenuates development of mechanical allodynia-like response in mice with neuropathic pain

por YAMAMOTO, Wataru, ITANO, Yasuhiro, KOBAYASHI, Tsunefumi, MIURA, Daishiro, KASAHARA, Yoshinori
Publicado 2015

Disruptions in hepatic glucose metabolism are involved in the diminished efficacy after chronic treatment with glucokinase activator

por Tsumura, Yoshinori, Tsushima, Yu, Tamura, Azusa, Kato, Hirotsugu, Kobayashi, Tsunefumi
Publicado 2022

Febuxostat, a novel xanthine oxidoreductase inhibitor, improves hypertension and endothelial dysfunction in spontaneously hypertensive rats

por Shirakura, Takashi, Nomura, Johji, Matsui, Chieko, Kobayashi, Tsunefumi, Tamura, Mizuho, Masuzaki, Hiroaki
Publicado 2016

TMG-123, a novel glucokinase activator, exerts durable effects on hyperglycemia without increasing triglyceride in diabetic animal models

por Tsumura, Yoshinori, Tsushima, Yu, Tamura, Azusa, Hasebe, Makiko, Kanou, Masanobu, Kato, Hirotsugu, Kobayashi, Tsunefumi
Publicado 2017

Abaloparatide Exerts Bone Anabolic Effects with Less Stimulation of Bone Resorption-Related Factors: A Comparison with Teriparatide

por Makino, Akito, Takagi, Hideko, Takahashi, Yoshimasa, Hase, Naoki, Sugiyama, Hiroyuki, Yamana, Kei, Kobayashi, Tsunefumi
Publicado 2018

Xanthine Oxidase Inhibition by Febuxostat Attenuates Experimental Atherosclerosis in Mice

por Nomura, Johji, Busso, Nathalie, Ives, Annette, Matsui, Chieko, Tsujimoto, Syunsuke, Shirakura, Takashi, Tamura, Mizuho, Kobayashi, Tsunefumi, So, Alexander, Yamanaka, Yoshihiro
Publicado 2014

Chymase Mediates Injury and Mitochondrial Damage in Cardiomyocytes during Acute Ischemia/Reperfusion in the Dog

por Zheng, Junying, Wei, Chih-Chang, Hase, Naoki, Shi, Ke, Killingsworth, Cheryl R., Litovsky, Silvio H., Powell, Pamela C., Kobayashi, Tsunefumi, Ferrario, Carlos M., Rab, Andras, Aban, Inmaculada, Collawn, James F., Dell'Italia, Louis J.
Publicado 2014