A Phase 1 randomized study on the safety and pharmacokinetics of OCS-05, a neuroprotective disease modifying treatment for Acute Optic Neuritis and Multiple Sclerosis

por Villoslada, Pablo, Masso, Mar, Paris, Stephane, Hutchings, Simon, Koch, Annelize
Publicado 2023

First-in-human studies of seletalisib, an orally bioavailable small-molecule PI3Kδ inhibitor for the treatment of immune and inflammatory diseases

por Helmer, Eric, Watling, Mark, Jones, Emma, Tytgat, Dominique, Jones, Mark, Allen, Rodger, Payne, Andrew, Koch, Annelize, Healy, Eugene
Publicado 2017

Neuroendocrine and sympathetic responses to an orexin receptor antagonist, SB-649868, and Alprazolam following insulin-induced hypoglycemia in humans

por Patel, Ameera X., Miller, Sam R., Nathan, Pradeep J., Kanakaraj, Ponmani, Napolitano, Antonella, Lawrence, Philip, Koch, Annelize, Bullmore, Edward T.
Publicado 2014

Safety, tolerability, pharmacokinetics and pharmacodynamics of the anti‐CD38 cytolytic antibody TAK‐079 in healthy subjects

por Fedyk, Eric R., Zhao, Lin, Koch, Annelize, Smithson, Glennda, Estevam, Jose, Chen, Grace, Lahu, Gezim, Roepcke, Stefan, Lin, Jianchang, Mclean, Lachy
Publicado 2020

GP2015, a proposed etanercept biosimilar: Pharmacokinetic similarity to its reference product and comparison of its autoinjector device with prefilled syringes

por von Richter, Oliver, Skerjanec, Andrej, Afonso, Miguel, Sanguino Heinrich, Sabine, Poetzl, Johann, Woehling, Heike, Velinova, Maria, Koch, Annelize, Kollins, Dmitrij, Macke, Lars, Wuerth, Guido
Publicado 2016

The Association for Human Pharmacology in the Pharmaceutical Industry London Meeting October 2019: Impending Change, Innovation, and Future Challenges

por Khan, Shahzadgai, Albayaty, Muna, Bush, James, Cheriyan, Joseph, Cromie, Anthea, Koch, Annelize, Hammond, Michael, Mair, Stuart, Lorch, Ulrike, Stringer, Steffan, Taubel, Jorg, Hardman, Timothy C.
Publicado 2020

The Association for Human Pharmacology in the Pharmaceutical Industry London Meeting 2018: Brexit and Other Challenges in Early Phase Drug Development

por Reijntjes, Susan, Albayaty, Muna, Bush, James, Cheriyan, Joseph, Cromie, Anthea, Koch, Annelize, Hammond, Michael, Mair, Stuart, Scholes, Peter, Lorch, Ulrike, Stringer, Steffan, Taubel, Jorg, Hardman, Timothy C.
Publicado 2018

Neural and Behavioral Effects of a Novel Mu Opioid Receptor Antagonist in Binge-Eating Obese People

por Cambridge, Victoria C., Ziauddeen, Hisham, Nathan, Pradeep J., Subramaniam, Naresh, Dodds, Chris, Chamberlain, Samuel R., Koch, Annelize, Maltby, Kay, Skeggs, Andrew L., Napolitano, Antonella, Farooqi, I. Sadaf, Bullmore, Edward T., Fletcher, Paul C.
Publicado 2013