Collapsin response mediator protein-2 plays a major protective role in acute axonal degeneration

por Zhang, Jian-Nan, Koch, Jan C.
Publicado 2017

Axonal degeneration as a therapeutic target in the CNS

por Lingor, Paul, Koch, Jan C., Tönges, Lars, Bähr, Mathias
Publicado 2012

X-ray fluorescence analysis of iron and manganese distribution in primary dopaminergic neurons

por Dučić, Tanja, Barski, Elisabeth, Salome, Murielle, Koch, Jan C, Bähr, Mathias, Lingor, Paul
Publicado 2013

Compassionate Use of the ROCK Inhibitor Fasudil in Three Patients With Amyotrophic Lateral Sclerosis

por Koch, Jan C., Kuttler, Josua, Maass, Fabian, Lengenfeld, Teresa, Zielke, Eirini, Bähr, Mathias, Lingor, Paul
Publicado 2020

Rho Kinase Inhibition with Fasudil in the SOD1(G93A) Mouse Model of Amyotrophic Lateral Sclerosis—Symptomatic Treatment Potential after Disease Onset

por Günther, René, Balck, Alexander, Koch, Jan C., Nientiedt, Tobias, Sereda, Michael, Bähr, Mathias, Lingor, Paul, Tönges, Lars
Publicado 2017

Inhibition of rho kinase enhances survival of dopaminergic neurons and attenuates axonal loss in a mouse model of Parkinson’s disease

por Tönges, Lars, Frank, Tobias, Tatenhorst, Lars, Saal, Kim A., Koch, Jan C., Szegő, Éva M., Bähr, Mathias, Weishaupt, Jochen H., Lingor, Paul
Publicado 2012

Calpain-mediated cleavage of collapsin response mediator protein-2 drives acute axonal degeneration

por Zhang, Jian-Nan, Michel, Uwe, Lenz, Christof, Friedel, Caroline C., Köster, Sarah, d’Hedouville, Zara, Tönges, Lars, Urlaub, Henning, Bähr, Mathias, Lingor, Paul, Koch, Jan C.
Publicado 2016

Fasudil attenuates aggregation of α-synuclein in models of Parkinson’s disease

por Tatenhorst, Lars, Eckermann, Katrin, Dambeck, Vivian, Fonseca-Ornelas, Luis, Walle, Hagen, Lopes da Fonseca, Tomás, Koch, Jan C., Becker, Stefan, Tönges, Lars, Bähr, Mathias, Outeiro, Tiago F., Zweckstetter, Markus, Lingor, Paul
Publicado 2016

ROCK-ALS: Protocol for a Randomized, Placebo-Controlled, Double-Blind Phase IIa Trial of Safety, Tolerability and Efficacy of the Rho Kinase (ROCK) Inhibitor Fasudil in Amyotrophic...

por Lingor, Paul, Weber, Markus, Camu, William, Friede, Tim, Hilgers, Reinhard, Leha, Andreas, Neuwirth, Christoph, Günther, René, Benatar, Michael, Kuzma-Kozakiewicz, Magdalena, Bidner, Helen, Blankenstein, Christiane, Frontini, Roberto, Ludolph, Albert, Koch, Jan C.
Publicado 2019

Neurochemical markers in CSF of adolescent and adult SMA patients undergoing nusinersen treatment

por Wurster, Claudia D., Günther, René, Steinacker, Petra, Dreyhaupt, Jens, Wollinsky, Kurt, Uzelac, Zeljko, Witzel, Simon, Kocak, Tugrul, Winter, Benedikt, Koch, Jan C., Lingor, Paul, Petri, Susanne, Ludolph, Albert C., Hermann, Andreas, Otto, Markus
Publicado 2019

Glial fibrillary acidic protein in cerebrospinal fluid of patients with spinal muscular atrophy

por Freigang, Maren, Steinacker, Petra, Wurster, Claudia D., Schreiber‐Katz, Olivia, Osmanovic, Alma, Petri, Susanne, Koch, Jan C., Rostásy, Kevin, Huss, André, Tumani, Hayrettin, Winter, Benedikt, Falkenburger, Björn, Ludolph, Albert C., Otto, Markus, Hermann, Andreas, Günther, René
Publicado 2022

Routine Cerebrospinal Fluid (CSF) Parameters in Patients With Spinal Muscular Atrophy (SMA) Treated With Nusinersen

por Wurster, Claudia D., Koch, Jan C., Cordts, Isabell, Dreyhaupt, Jens, Otto, Markus, Uzelac, Zeljko, Witzel, Simon, Winter, Benedikt, Kocak, Tugrul, Schocke, Michael, Weydt, Patrick, Wollinsky, Kurt, Ludolph, Albert C., Deschauer, Marcus, Lingor, Paul, Tumani, Hayrettin, Hermann, Andreas, Günther, René
Publicado 2019

Serum creatine kinase and creatinine in adult spinal muscular atrophy under nusinersen treatment

por Freigang, Maren, Wurster, Claudia D., Hagenacker, Tim, Stolte, Benjamin, Weiler, Markus, Kamm, Christoph, Schreiber‐Katz, Olivia, Osmanovic, Alma, Petri, Susanne, Kowski, Alexander, Meyer, Thomas, Koch, Jan C., Cordts, Isabell, Deschauer, Marcus, Lingor, Paul, Aust, Elisa, Petzold, Daniel, Ludolph, Albert C., Falkenburger, Björn, Hermann, Andreas, Günther, René
Publicado 2021

Spectrum and frequency of genetic variants in sporadic amyotrophic lateral sclerosis

por Ruf, Wolfgang P, Boros, Matej, Freischmidt, Axel, Brenner, David, Grozdanov, Veselin, de Meirelles, Joao, Meyer, Thomas, Grehl, Torsten, Petri, Susanne, Grosskreutz, Julian, Weyen, Ute, Guenther, Rene, Regensburger, Martin, Hagenacker, Tim, Koch, Jan C, Emmer, Alexander, Roediger, Annekathrin, Steinbach, Robert, Wolf, Joachim, Weishaupt, Jochen H, Lingor, Paul, Deschauer, Marcus, Cordts, Isabell, Klopstock, Thomas, Reilich, Peter, Schoeberl, Florian, Schrank, Berthold, Zeller, Daniel, Hermann, Andreas, Knehr, Antje, Günther, Kornelia, Dorst, Johannes, Schuster, Joachim, Siebert, Reiner, Ludolph, Albert C, Müller, Kathrin
Publicado 2023