HSV-1 Oncolytic Viruses from Bench to Bedside: An Overview of Current Clinical Trials

por Koch, Marilin S., Lawler, Sean E., Chiocca, E. Antonio
Publicado 2020

Uncovering transcriptomic landscape alterations of CAN-2409 in in vitro and in vivo glioma models

por Koch, Marilin S., Zdioruk, Mykola, Nowicki, Michal O., Hoetker, Michael S., Herbert, Zachary T., Barone, Francesca, Tak, Paul P., Chiocca, E. Antonio, Tabatabai, Ghazaleh, Lawler, Sean E.
Publicado 2023

Measles Virus-Based Treatments Trigger a Pro-inflammatory Cascade and a Distinctive Immunopeptidome in Glioblastoma

por Rajaraman, Srinath, Canjuga, Denis, Ghosh, Michael, Codrea, Marius Cosmin, Sieger, Raika, Wedekink, Florian, Tatagiba, Marcos, Koch, Marilin, Lauer, Ulrich M., Nahnsen, Sven, Rammensee, Hans-Georg, Mühlebach, Michael D., Stevanovic, Stefan, Tabatabai, Ghazaleh
Publicado 2018

Systemic high-dose dexamethasone treatment may modulate the efficacy of intratumoral viral oncolytic immunotherapy in glioblastoma models

por Koch, Marilin S, Zdioruk, Mykola, Nowicki, Michal O, Griffith, Alec M, Aguilar, Estuardo, Aguilar, Laura K, Guzik, Brian W, Barone, Francesca, Tak, Paul P, Tabatabai, Ghazaleh, Lederer, James A, Chiocca, E Antonio, Lawler, Sean
Publicado 2022

Targeting CSF1R Alone or in Combination with PD1 in Experimental Glioma

por Przystal, Justyna M., Becker, Hannes, Canjuga, Denis, Tsiami, Foteini, Anderle, Nicole, Keller, Anna-Lena, Pohl, Anja, Ries, Carola H., Schmittnaegel, Martina, Korinetska, Nataliya, Koch, Marilin, Schittenhelm, Jens, Tatagiba, Marcos, Schmees, Christian, Beck, Susanne C., Tabatabai, Ghazaleh
Publicado 2021

PPRX-1701, a nanoparticle formulation of 6′-bromoindirubin acetoxime, improves delivery and shows efficacy in preclinical GBM models

por Zdioruk, Mykola, Jimenez-Macias, Jorge-Luis, Nowicki, Michal Oskar, Manz, Katherine E., Pennell, Kurt D., Koch, Marilin S., Finkelberg, Tomer, Wu, Bin, Boucher, Paul, Takeda, Yuji, Li, Weiyi, Piranlioglu, Raziye, Ling, Alexander L., Chiocca, E. Antonio, Lawler, Sean E.
Publicado 2023

Perturbing DDR signaling enhances cytotoxic effects of local oncolytic virotherapy and modulates the immune environment in glioma

por Koch, Marilin S., Zdioruk, Mykola, Nowicki, Michal O., Griffith, Alec M., Aguilar-Cordova, Estuardo, Aguilar, Laura K., Guzik, Brian W., Barone, Francesca, Tak, Paul Peter, Schregel, Katharina, Hoetker, Michael S., Lederer, James A., Chiocca, E. Antonio, Tabatabai, Ghazaleh, Lawler, Sean E.
Publicado 2022

Experimental glioma with high bHLH expression harbor increased replicative stress and are sensitive toward ATR inhibition

por Koch, Marilin Sophia, Czemmel, Stefan, Lennartz, Felix, Beyeler, Sarah, Rajaraman, Srinath, Przystal, Justyna Magdalena, Govindarajan, Parameswari, Canjuga, Denis, Neumann, Manfred, Rizzu, Patrizia, Zwirner, Stefan, Hoetker, Michael Stefan, Zender, Lars, Walter, Bianca, Tatagiba, Marcos, Raineteau, Olivier, Heutink, Peter, Nahnsen, Sven, Tabatabai, Ghazaleh
Publicado 2020