Elucidating the Aβ42 Anti-Aggregation Mechanism of Action of Tramiprosate in Alzheimer’s Disease: Integrating Molecular Analytical Methods, Pharmacokinetic and Clinical Data

por Kocis, Petr, Tolar, Martin, Yu, Jeremy, Sinko, William, Ray, Soumya, Blennow, Kaj, Fillit, Howard, Hey, John A.
Publicado 2017

Discovery and Identification of an Endogenous Metabolite of Tramiprosate and Its Prodrug ALZ-801 that Inhibits Beta Amyloid Oligomer Formation in the Human Brain

por Hey, John A., Kocis, Petr, Hort, Jakub, Abushakra, Susan, Power, Aidan, Vyhnálek, Martin, Yu, Jeremy Y., Tolar, Martin
Publicado 2018

Clinical Pharmacokinetics and Safety of ALZ-801, a Novel Prodrug of Tramiprosate in Development for the Treatment of Alzheimer’s Disease

por Hey, John A., Yu, Jeremy Y., Versavel, Mark, Abushakra, Susan, Kocis, Petr, Power, Aidan, Kaplan, Paul L., Amedio, John, Tolar, Martin
Publicado 2017