Transgenic Mouse Model with Deficient Mitochondrial Polymerase Exhibits Reduced State IV Respiration and Enhanced Cardiac Fibrosis

por Koczor, Christopher A., Torres, Rebecca A., Fields, Earl, Qin, Qianhong, Park, Jade, Ludaway, Tomika, Russ, Rodney, Lewis, William
Publicado 2012

Live Cell Detection of Poly(ADP-Ribose) for Use in Genetic and Genotoxic Compound Screens

por Koczor, Christopher A., Haider, Aaron J., Saville, Kate M., Li, Jianfeng, Andrews, Joel F., Beiser, Alison V., Sobol, Robert W.
Publicado 2022

Overcoming Temozolomide Resistance in Glioblastoma via Enhanced NAD(+) Bioavailability and Inhibition of Poly-ADP-Ribose Glycohydrolase

por Li, Jianfeng, Koczor, Christopher A., Saville, Kate M., Hayat, Faisal, Beiser, Alison, McClellan, Steven, Migaud, Marie E., Sobol, Robert W.
Publicado 2022

Stability and sub-cellular localization of DNA polymerase β is regulated by interactions with NQO1 and XRCC1 in response to oxidative stress

por Fang, Qingming, Andrews, Joel, Sharma, Nidhi, Wilk, Anna, Clark, Jennifer, Slyskova, Jana, Koczor, Christopher A, Lans, Hannes, Prakash, Aishwarya, Sobol, Robert W
Publicado 2019

Temporal dynamics of base excision/single-strand break repair protein complex assembly/disassembly are modulated by the PARP/NAD(+)/SIRT6 axis

por Koczor, Christopher A., Saville, Kate M., Andrews, Joel F., Clark, Jennifer, Fang, Qingming, Li, Jianfeng, Al-Rahahleh, Rasha Q., Ibrahim, Md, McClellan, Steven, Makarov, Mikhail V., Migaud, Marie E., Sobol, Robert W.
Publicado 2021

NAD(+) bioavailability mediates PARG inhibition-induced replication arrest, intra S-phase checkpoint and apoptosis in glioma stem cells

por Li, Jianfeng, M. Saville, Kate, Ibrahim, Md, Zeng, Xuemei, McClellan, Steve, Angajala, Anusha, Beiser, Alison, Andrews, Joel F, Sun, Mai, Koczor, Christopher A, Clark, Jennifer, Hayat, Faisal, Makarov, Mikhail V, Wilk, Anna, Yates, Nathan A, Migaud, Marie E, Sobol, Robert W
Publicado 2021