Reasoning over genetic variance information in cause-and-effect models of neurodegenerative diseases

por Naz, Mufassra, Kodamullil, Alpha Tom, Hofmann-Apitius, Martin
Publicado 2016

Comorbidity Analysis between Alzheimer’s Disease and Type 2 Diabetes Mellitus (T2DM) Based on Shared Pathways and the Role of T2DM Drugs

por Karki, Reagon, Kodamullil, Alpha Tom, Hofmann-Apitius, Martin
Publicado 2017

Multi-ontology embeddings approach on human-aligned multi-ontologies representation for gene-disease associations prediction()

por Wang, Yihao, Wegner, Philipp, Domingo-Fernández, Daniel, Tom Kodamullil, Alpha
Publicado 2023

Computational Modelling Approaches on Epigenetic Factors in Neurodegenerative and Autoimmune Diseases and Their Mechanistic Analysis

por Khanam Irin, Afroza, Tom Kodamullil, Alpha, Gündel, Michaela, Hofmann-Apitius, Martin
Publicado 2015

Quantifying mechanisms in neurodegenerative diseases (NDDs) using candidate mechanism perturbation amplitude (CMPA) algorithm

por Karki, Reagon, Kodamullil, Alpha Tom, Hoyt, Charles Tapley, Hofmann-Apitius, Martin
Publicado 2019

On the influence of several factors on pathway enrichment analysis

por Mubeen, Sarah, Tom Kodamullil, Alpha, Hofmann-Apitius, Martin, Domingo-Fernández, Daniel
Publicado 2022

Of Mice and Men: Comparative Analysis of Neuro-Inflammatory Mechanisms in Human and Mouse Using Cause-and-Effect Models

por Kodamullil, Alpha Tom, Iyappan, Anandhi, Karki, Reagon, Madan, Sumit, Younesi, Erfan, Hofmann-Apitius, Martin
Publicado 2017

DecoPath: a web application for decoding pathway enrichment analysis

por Mubeen, Sarah, Bharadhwaj, Vinay S, Gadiya, Yojana, Hofmann-Apitius, Martin, Kodamullil, Alpha T, Domingo-Fernández, Daniel
Publicado 2021

Using Drugs as Molecular Probes: A Computational Chemical Biology Approach in Neurodegenerative Diseases

por Emon, Mohammad Asif Emran Khan, Kodamullil, Alpha Tom, Karki, Reagon, Younesi, Erfan, Hofmann-Apitius, Martin
Publicado 2017

Data-Driven Modeling of Knowledge Assemblies in Understanding Comorbidity Between Type 2 Diabetes Mellitus and Alzheimer’s Disease

por Karki, Reagon, Madan, Sumit, Gadiya, Yojana, Domingo-Fernández, Daniel, Kodamullil, Alpha Tom, Hofmann-Apitius, Martin
Publicado 2020

Towards a global investigation of transcriptomic signatures through co-expression networks and pathway knowledge for the identification of disease mechanisms

por Figueiredo, Rebeca Queiroz, Raschka, Tamara, Kodamullil, Alpha Tom, Hofmann-Apitius, Martin, Mubeen, Sarah, Domingo-Fernández, Daniel
Publicado 2021

Using predictive machine learning models for drug response simulation by calibrating patient-specific pathway signatures

por Golriz Khatami, Sepehr, Mubeen, Sarah, Bharadhwaj, Vinay Srinivas, Kodamullil, Alpha Tom, Hofmann-Apitius, Martin, Domingo-Fernández, Daniel
Publicado 2021

Contribution of syndecans to cellular uptake and fibrillation of α-synuclein and tau

por Hudák, Anett, Kusz, Erzsébet, Domonkos, Ildikó, Jósvay, Katalin, Kodamullil, Alpha Tom, Szilák, László, Hofmann-Apitius, Martin, Letoha, Tamás
Publicado 2019

Elucidating gene expression patterns across multiple biological contexts through a large-scale investigation of transcriptomic datasets

por Figueiredo, Rebeca Queiroz, del Ser, Sara Díaz, Raschka, Tamara, Hofmann-Apitius, Martin, Kodamullil, Alpha Tom, Mubeen, Sarah, Domingo-Fernández, Daniel
Publicado 2022

Design of the formalized and integrated Alzheimer’s Disease Ontology and its application in retrieving textual data via text mining

por Zhang, Bide, Lage-Rupprecht, Vanessa, Wegner, Philipp, Sargsyan, Astghik, Gebel, Stephan, Jacobs, Marc, Klein, Jürgen, Hofmann-Apitius, Martin, Tom Kodamullil, Alpha
Publicado 2023

COVID-19 Knowledge Graph: a computable, multi-modal, cause-and-effect knowledge model of COVID-19 pathophysiology

por Domingo-Fernández, Daniel, Baksi, Shounak, Schultz, Bruce, Gadiya, Yojana, Karki, Reagon, Raschka, Tamara, Ebeling, Christian, Hofmann-Apitius, Martin, Kodamullil, Alpha Tom
Publicado 2020

Exploring the Complex Network of Heme-Triggered Effects on the Blood Coagulation System

por Mubeen, Sarah, Domingo-Fernández, Daniel, Díaz del Ser, Sara, Solanki, Dhwani M., Kodamullil, Alpha T., Hofmann-Apitius, Martin, Hopp, Marie-T., Imhof, Diana
Publicado 2022

Linking COVID-19 and Heme-Driven Pathophysiologies: A Combined Computational–Experimental Approach

por Hopp, Marie-Thérèse, Domingo-Fernández, Daniel, Gadiya, Yojana, Detzel, Milena S., Graf, Regina, Schmalohr, Benjamin F., Kodamullil, Alpha T., Imhof, Diana, Hofmann-Apitius, Martin
Publicado 2021

A Systems Biology Approach for Hypothesizing the Effect of Genetic Variants on Neuroimaging Features in Alzheimer’s Disease

por Golriz Khatami, Sepehr, Domingo-Fernández, Daniel, Mubeen, Sarah, Hoyt, Charles Tapley, Robinson, Christine, Karki, Reagon, Iyappan, Anandhi, Kodamullil, Alpha Tom, Hofmann-Apitius, Martin
Publicado 2021

PDON: Parkinson’s disease ontology for representation and modeling of the Parkinson’s disease knowledge domain

por Younesi, Erfan, Malhotra, Ashutosh, Gündel, Michaela, Scordis, Phil, Kodamullil, Alpha Tom, Page, Matt, Müller, Bernd, Springstubbe, Stephan, Wüllner, Ullrich, Scheller, Dieter, Hofmann-Apitius, Martin
Publicado 2015