Transmembrane Domain Single-Nucleotide Polymorphisms Impair Expression and Transport Activity of ABC Transporter ABCG2

por Sjöstedt, Noora, van den Heuvel, Jeroen J. M. W., Koenderink, Jan B., Kidron, Heidi
Publicado 2017

Development of a physiologically-based pharmacokinetic pediatric brain model for prediction of cerebrospinal fluid drug concentrations and the influence of meningitis

por Verscheijden, Laurens F. M., Koenderink, Jan B., de Wildt, Saskia N., Russel, Frans G. M.
Publicado 2019

Differences in P-glycoprotein activity in human and rodent blood–brain barrier assessed by mechanistic modelling

por Verscheijden, Laurens F. M., Koenderink, Jan B., de Wildt, Saskia N., Russel, Frans G. M.
Publicado 2021

PfMDR2 and PfMDR5 are dispensable for Plasmodium falciparum asexual parasite multiplication but change in vitro susceptibility to anti-malarial drugs

por van der Velden, Maarten, Rijpma, Sanna R, Russel, Frans GM, Sauerwein, Robert W, Koenderink, Jan B
Publicado 2015

The feline bile salt export pump: a structural and functional comparison with canine and human Bsep/BSEP

por van Beusekom, Cyrina D, van den Heuvel, Jeroen JMW, Koenderink, Jan B, Schrickx, Johannes A, Russel, Frans GM
Publicado 2013

Transporter-Mediated Cellular Distribution of Tyrosine Kinase Inhibitors as a Potential Resistance Mechanism in Chronic Myeloid Leukemia

por Verhagen, Noor E., Koenderink, Jan B., Blijlevens, Nicole M. A., Janssen, Jeroen J. W. M., Russel, Frans G. M.
Publicado 2023

Atovaquone and quinine anti-malarials inhibit ATP binding cassette transporter activity

por Rijpma, Sanna R, van den Heuvel, Jeroen JMW, van der Velden, Maarten, Sauerwein, Robert W, Russel, Frans GM, Koenderink, Jan B
Publicado 2014

The Effect of Single Nucleotide Variations in the Transmembrane Domain of OATP1B1 on in vitro Functionality

por Kiander, Wilma, Vellonen, Kati-Sisko, Malinen, Melina M., Gynther, Mikko, Hagström, Marja, Bhattacharya, Madhushree, Auriola, Seppo, Koenderink, Jan B., Kidron, Heidi
Publicado 2021

Localization of the ATP-binding cassette (ABC) transport proteins PfMRP1, PfMRP2, and PfMDR5 at the Plasmodium falciparum plasma membrane

por Kavishe, Reginald A, van den Heuvel, Jeroen MW, van de Vegte-Bolmer, Marga, Luty, Adrian JF, Russel, Frans GM, Koenderink, Jan B
Publicado 2009

Human multidrug resistance protein 4 (MRP4) is a cellular efflux transporter for paracetamol glutathione and cysteine conjugates

por Koenderink, Jan B., van den Heuvel, Jeroen J. M. W., Bilos, Ab, Vredenburg, Galvin, Vermeulen, Nico P. E., Russel, Frans G. M.
Publicado 2020

Physiologically based pharmacokinetic/pharmacodynamic model for the prediction of morphine brain disposition and analgesia in adults and children

por Verscheijden, Laurens F. M., Litjens, Carlijn H. C., Koenderink, Jan B., Mathijssen, Ron H. J., Verbeek, Marcel M., de Wildt, Saskia N., Russel, Frans G. M.
Publicado 2021

FXYD2 and Na,K-ATPase Expression in Isolated Human Proximal Tubular Cells: Disturbed Upregulation on Renal Hypomagnesemia?

por Cairo, Edinio R., Swarts, Herman G. P., Wilmer, Martijn J. G., Willems, Peter H. G. M., Levtchenko, Elena N., De Pont, Jan Joep H. H. M., Koenderink, Jan B.
Publicado 2009

Perfluoroalkyl substances (PFASs) are substrates of the renal human organic anion transporter 4 (OAT4)

por Louisse, Jochem, Dellafiora, Luca, van den Heuvel, Jeroen J. M. W., Rijkers, Deborah, Leenders, Liz, Dorne, Jean-Lou C. M., Punt, Ans, Russel, Frans G. M., Koenderink, Jan B.
Publicado 2022

Proguanil and cycloguanil are organic cation transporter and multidrug and toxin extrusion substrates

por van der Velden, Maarten, Bilos, Albert, van den Heuvel, Jeroen J. M. W., Rijpma, Sanna R., Hurkmans, Evelien G. E., Sauerwein, Robert W., Russel, Frans G. M., Koenderink, Jan B.
Publicado 2017

Localization of breast cancer resistance protein (Bcrp) in endocrine organs and inhibition of its transport activity by steroid hormones

por Dankers, Anita C. A., Sweep, Fred C. G. J., Pertijs, Jeanne C. L. M., Verweij, Vivienne, van den Heuvel, Jeroen J. M. W., Koenderink, Jan B., Russel, Frans G. M., Masereeuw, Rosalinde
Publicado 2012

Trends in chloroquine resistance marker, Pfcrt-K76T mutation ten years after chloroquine withdrawal in Tanzania

por Mohammed, Asia, Ndaro, Arnold, Kalinga, Akili, Manjurano, Alphaxard, Mosha, Jackline F, Mosha, Dominick F, van Zwetselaar, Marco, Koenderink, Jan B, Mosha, Frank W, Alifrangis, Michael, Reyburn, Hugh, Roper, Cally, Kavishe, Reginald A
Publicado 2013

Completing the Enalaprilat Excretion Pathway—Renal Handling by the Proximal Tubule

por Smeets, Nori J. L., Litjens, Carlijn H. C., van den Heuvel, Jeroen J. M. W., van Hove, Hedwig, van den Broek, Petra, Russel, Frans G. M., Koenderink, Jan B., de Wildt, Saskia N.
Publicado 2020

Rifampicin Alters Metformin Plasma Exposure but Not Blood Glucose Levels in Diabetic Tuberculosis Patients

por te Brake, Lindsey H.M., Yunivita, Vycke, Livia, Resvi, Soetedjo, Nanny, van Ewijk‐Beneken Kolmer, Eleonora, Koenderink, Jan B., Burger, David M., Santoso, Prayudi, van Crevel, Reinout, Alisjahbana, Bachti, Aarnoutse, Rob E., Ruslami, Rovina
Publicado 2018

Physiologically-Based Pharmacokinetic Modelling to Predict the Pharmacokinetics and Pharmacodynamics of Linezolid in Adults and Children with Tuberculous Meningitis

por Litjens, Carlijn H. C., Verscheijden, Laurens F. M., Svensson, Elin M., van den Broek, Petra H. H., van Hove, Hedwig, Koenderink, Jan B., Russel, Frans G. M., Aarnoutse, Rob E., te Brake, Lindsey H. M.
Publicado 2023

Prediction of Moxifloxacin Concentrations in Tuberculosis Patient Populations by Physiologically Based Pharmacokinetic Modeling

por Litjens, Carlijn H. C., Verscheijden, Laurens F. M., Bolwerk, Celine, Greupink, Rick, Koenderink, Jan B., van den Broek, Petra H. H., van den Heuvel, Jeroen J. M. W., Svensson, Elin M., Boeree, Martin J., Magis‐Escurra, Cecile, Hoefsloot, Wouter, van Crevel, Reinout, van Laarhoven, Arjan, van Ingen, Jakko, Kuipers, Saskia, Ruslami, Rovina, Burger, David M., Russel, Frans G. M., Aarnoutse, Rob E., te Brake, Lindsey H. M.
Publicado 2021