Pharmacological Inhibitor of Notch Signaling Stabilizes the Progression of Small Abdominal Aortic Aneurysm in a Mouse Model

por Cheng, Jeeyun, Koenig, Sara N., Kuivaniemi, Helena S., Garg, Vidu, Hans, Chetan P.
Publicado 2014

Evidence of Aortopathy in Mice with Haploinsufficiency of Notch1 in Nos3-Null Background

por Koenig, Sara N., Bosse, Kevin M., Nadorlik, Holly A., Lilly, Brenda, Garg, Vidu
Publicado 2015

Endothelial Notch1 Is Required for Proper Development of the Semilunar Valves and Cardiac Outflow Tract

por Koenig, Sara N., Bosse, Kevin, Majumdar, Uddalak, Bonachea, Elizabeth M., Radtke, Freddy, Garg, Vidu
Publicado 2016

Developmental origins for semilunar valve stenosis identified in mice harboring congenital heart disease-associated GATA4 mutation

por LaHaye, Stephanie, Majumdar, Uddalak, Yasuhara, Jun, Koenig, Sara N., Matos-Nieves, Adrianna, Kumar, Rahul, Garg, Vidu
Publicado 2019

Arrhythmogenic Cardiomyopathy: Molecular Insights for Improved Therapeutic Design

por Stevens, Tyler L., Wallace, Michael J., El Refaey, Mona, Roberts, Jason D., Koenig, Sara N., Mohler, Peter J.
Publicado 2020

Mechanisms and Alterations of Cardiac Ion Channels Leading to Disease: Role of Ankyrin-B in Cardiac Function

por Sucharski, Holly C., Dudley, Emma K., Keith, Caullin B.R., El Refaey, Mona, Koenig, Sara N., Mohler, Peter J.
Publicado 2020

Isolation and characterization of a SARS-CoV-2 variant with a Q677H mutation in the spike protein

por Niu, Xiaoyu, Xu, Jiayu, Liu, Mingde, Tu, Huolin, Koenig, Sara N., Saif, Linda J., Jones, Daniel M., Wang, Qiuhong
Publicado 2022

Dynamic Heterogeneity of the Heart Valve Interstitial Cell Population in Mitral Valve Health and Disease

por Horne, Tori E., VandeKopple, Matthew, Sauls, Kimberly, Koenig, Sara N., Anstine, Lindsey J., Garg, Vidu, Norris, Russell A., Lincoln, Joy
Publicado 2015

Inhibitory Role of Notch1 in Calcific Aortic Valve Disease

por Acharya, Asha, Hans, Chetan P., Koenig, Sara N., Nichols, Haley A., Galindo, Cristi L., Garner, Harold R., Merrill, Walter H., Hinton, Robert B., Garg, Vidu
Publicado 2011

Congenital Heart Disease–Causing Gata4 Mutation Displays Functional Deficits In Vivo

por Misra, Chaitali, Sachan, Nita, McNally, Caryn Rothrock, Koenig, Sara N., Nichols, Haley A., Guggilam, Anuradha, Lucchesi, Pamela A., Pu, William T., Srivastava, Deepak, Garg, Vidu
Publicado 2012

MG53 Protein Protects Aortic Valve Interstitial Cells From Membrane Injury and Fibrocalcific Remodeling

por Adesanya, T. M. Ayodele, Russell, Melanie, Park, Ki Ho, Zhou, Xinyu, Sermersheim, Matthew A., Gumpper, Kristyn, Koenig, Sara N., Tan, Tao, Whitson, Bryan A., Janssen, Paul M. L., Lincoln, Joy, Zhu, Hua, Ma, Jianjie
Publicado 2019

Humanized Dsp ACM Mouse Model Displays Stress-Induced Cardiac Electrical and Structural Phenotypes

por Stevens, Tyler L., Manring, Heather R., Wallace, Michael J., Argall, Aaron, Dew, Trevor, Papaioannou, Peter, Antwi-Boasiako, Steve, Xu, Xianyao, Campbell, Stuart G., Akar, Fadi G., Borzok, Maegen A., Hund, Thomas J., Mohler, Peter J., Koenig, Sara N., El Refaey, Mona
Publicado 2022

Altered Expression of Zonula occludens-1 Affects Cardiac Na(+) Channels and Increases Susceptibility to Ventricular Arrhythmias

por El Refaey, Mona, Coles, Sara, Musa, Hassan, Stevens, Tyler L., Wallace, Michael J., Murphy, Nathaniel P., Antwi-Boasiako, Steve, Young, Lindsay J., Manring, Heather R., Curran, Jerry, Makara, Michael A., Sas, Kelli, Han, Mei, Koenig, Sara N., Skaf, Michel, Kline, Crystal F., Janssen, Paul M. L., Accornero, Federica, Borzok, Maegen A., Mohler, Peter J.
Publicado 2022