A mutation-led search for novel functional domains in MeCP2

por Guy, Jacky, Alexander-Howden, Beatrice, FitzPatrick, Laura, DeSousa, Dina, Koerner, Martha V, Selfridge, Jim, Bird, Adrian
Publicado 2018

Affinity for DNA Contributes to NLS Independent Nuclear Localization of MeCP2

por Lyst, Matthew J., Ekiert, Robert, Guy, Jacky, Selfridge, Jim, Koerner, Martha V., Merusi, Cara, De Sousa, Dina, Bird, Adrian
Publicado 2018

The molecular basis of variable phenotypic severity among common missense mutations causing Rett syndrome

por Brown, Kyla, Selfridge, Jim, Lagger, Sabine, Connelly, John, De Sousa, Dina, Kerr, Alastair, Webb, Shaun, Guy, Jacky, Merusi, Cara, Koerner, Martha V., Bird, Adrian
Publicado 2016

Radically truncated MeCP2 rescues Rett syndrome-like neurological defects

por Tillotson, Rebekah, Selfridge, Jim, Koerner, Martha V., Gadalla, Kamal K. E., Guy, Jacky, De Sousa, Dina, Hector, Ralph D., Cobb, Stuart R., Bird, Adrian
Publicado 2017

Toxicity of overexpressed MeCP2 is independent of HDAC3 activity

por Koerner, Martha V., FitzPatrick, Laura, Selfridge, Jim, Guy, Jacky, De Sousa, Dina, Tillotson, Rebekah, Kerr, Alastair, Sun, Zheng, Lazar, Mitchell A., Lyst, Matthew J., Bird, Adrian
Publicado 2018

An Orphan CpG Island Drives Expression of a let-7 miRNA Precursor with an Important Role in Mouse Development

por Koerner, Martha V., Chhatbar, Kashyap, Webb, Shaun, Cholewa-Waclaw, Justyna, Selfridge, Jim, De Sousa, Dina, Skarnes, Bill, Rosen, Barry, Thomas, Mark, Bottomley, Joanna, Ramirez-Solis, Ramiro, Lelliott, Christopher, Adams, David J., Bird, Adrian
Publicado 2019

Neuronal non-CG methylation is an essential target for MeCP2 function

por Tillotson, Rebekah, Cholewa-Waclaw, Justyna, Chhatbar, Kashyap, Connelly, John C., Kirschner, Sophie A., Webb, Shaun, Koerner, Martha V., Selfridge, Jim, Kelly, David A., De Sousa, Dina, Brown, Kyla, Lyst, Matthew J., Kriaucionis, Skirmantas, Bird, Adrian
Publicado 2021

A Downstream CpG Island Controls Transcript Initiation and Elongation and the Methylation State of the Imprinted Airn Macro ncRNA Promoter

por Koerner, Martha V., Pauler, Florian M., Hudson, Quanah J., Santoro, Federica, Sawicka, Anna, Guenzl, Philipp M., Stricker, Stefan H., Schichl, Yvonne M., Latos, Paulina A., Klement, Ruth M., Warczok, Katarzyna E., Wojciechowski, Jacek, Seiser, Christian, Kralovics, Robert, Barlow, Denise P.
Publicado 2012

Carbonyl reductase 1 amplifies glucocorticoid action in adipose tissue and impairs glucose tolerance in lean mice

por Bell, Rachel M.B., Villalobos, Elisa, Nixon, Mark, Miguelez-Crespo, Allende, Murphy, Lee, Fawkes, Angie, Coutts, Audrey, Sharp, Matthew G.F., Koerner, Martha V., Allan, Emma, Meijer, Onno C., Houtman, Renè, Odermatt, Alex, Beck, Katharina R., Denham, Scott G., Lee, Patricia, Homer, Natalie Z.M., Walker, Brian R., Morgan, Ruth A.
Publicado 2021