Respiratory virus–induced EGFR activation suppresses IRF1-dependent interferon λ and antiviral defense in airway epithelium

por Ueki, Iris F., Min-Oo, Gundula, Kalinowski, April, Ballon-Landa, Eric, Lanier, Lewis L., Nadel, Jay A., Koff, Jonathan L.
Publicado 2013

Bacteriophage Therapy for Pan-Drug-Resistant Pseudomonas aeruginosa in Two Persons With Cystic Fibrosis

por Hahn, Andrea, Sami, Iman, Chaney, Hollis, Koumbourlis, Anastassios C., Del Valle Mojica, Coralee, Cochrane, Claire, Chan, Benjamin K., Koff, Jonathan L.
Publicado 2023

Inhaled Bacteriophage Therapy for Multi-Drug Resistant Achromobacter

por Winzig, Franziska, Gandhi, Shiv, Lee, Alina, Würstle, Silvia, Stanley, Gail L., Capuano, Isabella, Neuringer, Isabel, Koff, Jonathan L., Turner, Paul E., Chan, Benjamin K.
Publicado 2022

Pharmacological modulation of the AKT/microRNA-199a-5p/CAV1 pathway ameliorates cystic fibrosis lung hyper-inflammation

por Zhang, Ping-xia, Cheng, Jijun, Zou, Siying, D’Souza, Anthony D., Koff, Jonathan L., Lu, Jun, Lee, Patty J., Krause, Diane S., Egan, Marie E., Bruscia, Emanuela M.
Publicado 2015

A Novel Zinc (II) Porphyrin Is Synergistic with PEV2 Bacteriophage against Pseudomonas aeruginosa Infections

por Geyer, Jessica, Krupa, Kristen A., Harris, Zachary M., Sun, Ying, Sharma, Lokesh, Würstle, Silvia, Hu, Buqu, Stanley, Gail, Rajagopalan, Govindarajan, Pellot, Erin, Koff, Jonathan L., Robinson, Jayne B.
Publicado 2023

Ezrin links CFTR to TLR4 signaling to orchestrate anti-bacterial immune response in macrophages

por Di Pietro, Caterina, Zhang, Ping-xia, O’Rourke, Timothy K., Murray, Thomas S., Wang, Lin, Britto, Clemente J., Koff, Jonathan L., Krause, Diane S., Egan, Marie E., Bruscia, Emanuela M.
Publicado 2017

Respiratory syncytial virus activates epidermal growth factor receptor to suppress interferon regulatory factor 1-dependent interferon-lambda and antiviral defense in airway epithe...

por Kalinowski, April, Galen, Benjamin T., Ueki, Iris F., Sun, Ying, Mulenos, Arielle, Osafo-Addo, Awo, Clark, Brian, Joerns, John, Liu, Wei, Nadel, Jay A., Cruz, Charles S. Dela, Koff, Jonathan L.
Publicado 2018

“Small” Intestinal Immunopathology Plays a “Big” Role in Lethal Cytokine Release Syndrome, and Its Modulation by Interferon-γ, IL-17A, and a Janus Kinase Inhibitor

por Kale, Shiv D., Mehrkens, Brittney N., Stegman, Molly M., Kastelberg, Bridget, Carnes, Henry, McNeill, Rachel J., Rizzo, Amy, Karyala, Saikumar V., Coutermarsh-Ott, Sheryl, Fretz, Jackie A., Sun, Ying, Koff, Jonathan L., Rajagopalan, Govindarajan
Publicado 2020

Metabolic Adaptation in Methicillin-Resistant Staphylococcus aureus Pneumonia

por Gabryszewski, Stanislaw J., Wong Fok Lung, Tania, Annavajhala, Medini K., Tomlinson, Kira L., Riquelme, Sebastian A., Khan, Ibrahim N., Noguera, Loreani P., Wickersham, Matthew, Zhao, Alison, Mulenos, Arielle M., Peaper, David, Koff, Jonathan L., Uhlemann, Anne-Catrin, Prince, Alice
Publicado 2019

Epidermal Growth Factor Receptor Inhibition Is Protective in Hyperoxia-Induced Lung Injury

por Harris, Zachary M., Sun, Ying, Joerns, John, Clark, Brian, Hu, Buqu, Korde, Asawari, Sharma, Lokesh, Shin, Hyeon Jun, Manning, Edward P., Placek, Lindsey, Unutmaz, Derya, Stanley, Gail, Chun, Hyung, Sauler, Maor, Rajagopalan, Govindarajan, Zhang, Xuchen, Kang, Min-Jong, Koff, Jonathan L.
Publicado 2022

COVID-19 bacteremic co-infection is a major risk factor for mortality, ICU admission, and mechanical ventilation

por Patton, Michael John, Orihuela, Carlos J., Harrod, Kevin S., Bhuiyan, Mohammad A. N., Dominic, Paari, Kevil, Christopher G., Fort, Daniel, Liu, Vincent X., Farhat, Maha, Koff, Jonathan L., Lal, Charitharth V., Gaggar, Anuj, Richter, Robert P., Erdmann, Nathaniel, Might, Matthew, Gaggar, Amit
Publicado 2023

I-SPY COVID adaptive platform trial for COVID-19 acute respiratory failure: rationale, design and operations

por Files, Daniel Clark, Matthay, Michael A, Calfee, Carolyn S, Aggarwal, Neil R, Asare, Adam L, Beitler, Jeremy R, Berger, Paul A, Burnham, Ellen L, Cimino, George, Coleman, Melissa H, Crippa, Alessio, Discacciati, Andrea, Gandotra, Sheetal, Gibbs, Kevin W, Henderson, Paul T, Ittner, Caroline A G, Jauregui, Alejandra, Khan, Kashif T, Koff, Jonathan L, Lang, Julie, LaRose, Mary, Levitt, Joe, Lu, Ruixiao, McKeehan, Jeffrey D, Meyer, Nuala J, Russell, Derek W, Thomas, Karl W, Eklund, Martin, Esserman, Laura J, Liu, Kathleen D
Publicado 2022