Neurons in Vulnerable Regions of the Alzheimer’s Disease Brain Display Reduced ATM Signaling123

por Shen, Xuting, Chen, Jianmin, Li, Jiali, Kofler, Julia, Herrup, Karl
Publicado 2016

Spectrum of Tau Pathologies in Huntington’s disease

por Baskota, Swikrity Upadhyay, Lopez, Oscar L., Greenamyre, J. Timothy, Kofler, Julia
Publicado 2019

Unveiling the Enigma: Exploring Risk Factors and Mechanisms for Psychotic Symptoms in Alzheimer’s Disease through Electronic Medical Records with Deep Learning Models

por Fan, Peihao, Miranda, Oshin, Qi, Xiguang, Kofler, Julia, Sweet, Robert A., Wang, Lirong
Publicado 2023

Receptor for Advanced Glycation End Products and its Inflammatory Ligands are Upregulated in Amyotrophic Lateral Sclerosis

por Juranek, Judyta K., Daffu, Gurdip K., Wojtkiewicz, Joanna, Lacomis, David, Kofler, Julia, Schmidt, Ann Marie
Publicado 2015

Improved Brain Pathology and Progressive Peripheral Neuropathy in a 15 Year Old Survivor of Infantile Krabbe Disease Treated With Umbilical Cord Transplantation

por Kofler, Julia, Beltran-Quintero, Maria L., Rugari, Anne, Zuccoli, Giulio, Klotz, Sarah, Escolar, Maria L.
Publicado 2022

Combination of antidepressants and antipsychotics as a novel treatment option for psychosis in Alzheimer's disease

por Fan, Peihao, Zeng, Lang, Ding, Ying, Kofler, Julia, Silverstein, Jonathan, Krivinko, Joshua, Sweet, Robert A., Wang, Lirong
Publicado 2023

Inclusion of African American/Black adults in a pilot brain proteomics study of Alzheimer’s disease

por Stepler, Kaitlyn E., Mahoney, Emily R., Kofler, Julia, Hohman, Timothy J., Lopez, Oscar L., Robinson, Renã A.S.
Publicado 2020

Amyloid fibril proteomics of AD brains reveals modifiers of aggregation and toxicity

por Upadhyay, Arun, Chhangani, Deepak, Rao, Nalini R., Kofler, Julia, Vassar, Robert, Rincon-Limas, Diego E., Savas, Jeffrey N.
Publicado 2023

Post-mortem analyses of PiB and flutemetamol in diffuse and cored amyloid-β plaques in Alzheimer’s disease

por Ikonomovic, Milos D., Buckley, Christopher J., Abrahamson, Eric E., Kofler, Julia K., Mathis, Chester A., Klunk, William E., Farrar, Gill
Publicado 2020

CD13 facilitates immune cell migration and aggravates acute injury but promotes chronic post-stroke recovery

por Nguyen, Justin N., Mohan, Eric C., Pandya, Gargee, Ali, Uzma, Tan, Chunfeng, Kofler, Julia K., Shapiro, Linda, Marrelli, Sean P., Chauhan, Anjali
Publicado 2023

Preventive immunization of aged and juvenile non-human primates to beta-amyloid

por Kofler, Julia, Lopresti, Brian, Janssen, Chris, Trichel, Anita M, Masliah, Eliezer, Finn, Olivera J, Salter, Russell D, Murdoch, Geoffrey H, Mathis, Chester A, Wiley, Clayton A
Publicado 2012

APOE2 orchestrated differences in transcriptomic and lipidomic profiles of postmortem AD brain

por Lefterov, Iliya, Wolfe, Cody M., Fitz, Nicholas F., Nam, Kyong Nyon, Letronne, Florent, Biedrzycki, Richard J., Kofler, Julia, Han, Xianlin, Wang, Jianing, Schug, Jonathan, Koldamova, Radosveta
Publicado 2019

Psychosis in Alzheimer's Disease Is Associated With Increased Excitatory Neuron Vulnerability and Post-transcriptional Mechanisms Altering Synaptic Protein Levels

por DeChellis-Marks, Michael R., Wei, Yue, Ding, Ying, Wolfe, Cody M., Krivinko, Joshua M., MacDonald, Matthew L., Lopez, Oscar L., Sweet, Robert A., Kofler, Julia
Publicado 2022

RNA dependent suppression of C9orf72 ALS/FTD associated neurodegeneration by Matrin-3

por Ramesh, Nandini, Daley, Elizabeth L., Gleixner, Amanda M., Mann, Jacob R., Kour, Sukhleen, Mawrie, Darilang, Anderson, Eric N., Kofler, Julia, Donnelly, Christopher J., Kiskinis, Evangelos, Pandey, Udai Bhan
Publicado 2020

Growth differentiation factor-11 supplementation improves survival and promotes recovery after ischemic stroke in aged mice

por Hudobenko, Jacob, Ganesh, Bhanu Priya, Jiang, Jianjun, Mohan, Eric C., Lee, Songmi, Sheth, Sunil, Morales, Diego, Zhu, Liang, Kofler, Julia K., Pautler, Robia G., McCullough, Louise D., Chauhan, Anjali
Publicado 2020

LRRK2 inhibition prevents endolysosomal deficits seen in human Parkinson’s disease

por Rocha, Emily M., De Miranda, Briana R., Castro, Sandra, Drolet, Robert, Hatcher, Nathan G., Yao, Lihang, Smith, Sean M., Keeney, Matthew T., Di Maio, Roberto, Kofler, Julia, Hastings, Teresa G., Greenamyre, J. Timothy
Publicado 2019

β-Galactosylceramidase Deficiency Causes Upregulation of Long Pentraxin-3 in the Central Nervous System of Krabbe Patients and Twitcher Mice

por Coltrini, Daniela, Chandran, Adwaid Manu Krishna, Belleri, Mirella, Poliani, Pietro L., Cominelli, Manuela, Pagani, Francesca, Capra, Miriam, Calza, Stefano, Prioni, Simona, Mauri, Laura, Prinetti, Alessandro, Kofler, Julia K., Escolar, Maria L., Presta, Marco
Publicado 2022

Impact of partial volume correction on the regional correspondence between in vivo [C-11]PiB PET and postmortem measures of Aβ load

por Minhas, Davneet S., Price, Julie C., Laymon, Charles M., Becker, Carl R., Klunk, William E., Tudorascu, Dana L., Abrahamson, Eric E., Hamilton, Ronald L., Kofler, Julia K., Mathis, Chester A., Lopez, Oscar L., Ikonomovic, Milos D.
Publicado 2018

Hippocampal sclerosis, TDP‐43, and the duration of the symptoms of dementia of AD patients

por Lopez, Oscar L., Kofler, Julia, Chang, YueFang, Berman, Sarah B., Becker, James T., Sweet, Robert A., Nadkarni, Neelesh, Patira, Riddhi, Kamboh, M. Ilyas, Cohen, Ann D., Snitz, Beth E., Kuller, Lewis H., Klunk, William E.
Publicado 2020

Deep learning from multiple experts improves identification of amyloid neuropathologies

por Wong, Daniel R., Tang, Ziqi, Mew, Nicholas C., Das, Sakshi, Athey, Justin, McAleese, Kirsty E., Kofler, Julia K., Flanagan, Margaret E., Borys, Ewa, White, Charles L., Butte, Atul J., Dugger, Brittany N., Keiser, Michael J.
Publicado 2022