The contradictory roles of macrophages in non-alcoholic fatty liver disease and primary liver cancer—Challenges and opportunities

por Kohlhepp, Marlene Sophia, Liu, Hanyang, Tacke, Frank, Guillot, Adrien
Publicado 2023

Deciphering the Immune Microenvironment on A Single Archival Formalin-Fixed Paraffin-Embedded Tissue Section by An Immediately Implementable Multiplex Fluorescence Immunostaining P...

por Guillot, Adrien, Kohlhepp, Marlene S., Bruneau, Alix, Heymann, Felix, Tacke, Frank
Publicado 2020

Differential impact of the dual CCR2/CCR5 inhibitor cenicriviroc on migration of monocyte and lymphocyte subsets in acute liver injury

por Puengel, Tobias, Krenkel, Oliver, Kohlhepp, Marlene, Lefebvre, Eric, Luedde, Tom, Trautwein, Christian, Tacke, Frank
Publicado 2017

Roles of CCR2 and CCR5 for Hepatic Macrophage Polarization in Mice With Liver Parenchymal Cell-Specific NEMO Deletion

por Bartneck, Matthias, Koppe, Christiane, Fech, Viktor, Warzecha, Klaudia T., Kohlhepp, Marlene, Huss, Sebastian, Weiskirchen, Ralf, Trautwein, Christian, Luedde, Tom, Tacke, Frank
Publicado 2020

Hepatic C-X-C chemokine receptor type 6–expressing innate lymphocytes limit detrimental myeloid hyperactivation in acute liver injury

por Heymann, Felix, Mossanen, Jana C., Peiseler, Moritz, Niemietz, Patricia M., Araujo David, Bruna, Krenkel, Oliver, Liepelt, Anke, Batista Carneiro, Matheus, Kohlhepp, Marlene S., Kubes, Paul, Tacke, Frank
Publicado 2023

Cyclin E1 in Murine and Human Liver Cancer: A Promising Target for Therapeutic Intervention during Tumour Progression

por Sonntag, Roland, Penners, Christian, Kohlhepp, Marlene, Haas, Ute, Lambertz, Daniela, Kroh, Andreas, Cramer, Thorsten, Ticconi, Fabio, Costa, Ivan G., Tacke, Frank, Gassler, Nikolaus, Trautwein, Christian, Liedtke, Christian
Publicado 2021

The Medium-Chain Fatty Acid Receptor GPR84 Mediates Myeloid Cell Infiltration Promoting Steatohepatitis and Fibrosis

por Puengel, Tobias, De Vos, Steve, Hundertmark, Jana, Kohlhepp, Marlene, Guldiken, Nurdan, Pujuguet, Philippe, Auberval, Marielle, Marsais, Florence, Shoji, Kenji F., Saniere, Laurent, Trautwein, Christian, Luedde, Tom, Strnad, Pavel, Brys, Reginald, Clément-Lacroix, Philippe, Tacke, Frank
Publicado 2020

Combined Therapy with a CCR2/CCR5 Antagonist and FGF21 Analogue Synergizes in Ameliorating Steatohepatitis and Fibrosis

por Puengel, Tobias, Lefere, Sander, Hundertmark, Jana, Kohlhepp, Marlene, Penners, Christian, Van de Velde, Frederique, Lapauw, Bruno, Hoorens, Anne, Devisscher, Lindsey, Geerts, Anja, Boehm, Stephanie, Zhao, Qihong, Krupinski, John, Charles, Edgar D., Zinker, Bradley, Tacke, Frank
Publicado 2022

Interleukin‐18 signaling promotes activation of hepatic stellate cells in mouse liver fibrosis

por Knorr, Jana, Kaufmann, Benedikt, Inzaugarat, Maria Eugenia, Holtmann, Theresa Maria, Geisler, Lukas, Hundertmark, Jana, Kohlhepp, Marlene Sophia, Boosheri, Laela M., Chilin‐Fuentes, Daisy R., Birmingham, Amanda, Fisch, Kathleen M., Schilling, Joel D., Loosen, Sven H., Trautwein, Christian, Roderburg, Christoph, Demir, Münevver, Tacke, Frank, Hoffman, Hal M., Feldstein, Ariel E., Wree, Alexander
Publicado 2023

Inhibition of LTβR-signalling activates Wnt-induced regeneration in lung

por Conlon, Thomas M., John-Schuster, Gerrit, Heide, Danijela, Pfister, Dominik, Lehmann, Mareike, Hu, Yan, Ertüz, Zeynep, Lopez, Martin A., Ansari, Meshal, Strunz, Maximilian, Mayr, Christoph, Ciminieri, Chiara, Costa, Rita, Kohlhepp, Marlene Sophia, Guillot, Adrien, Günes, Gizem, Jeridi, Aicha, Funk, Maja C., Beroshvili, Giorgi, Prokosch, Sandra, Hetzer, Jenny, Verleden, Stijn E., Alsafadi, Hani, Lindner, Michael, Burgstaller, Gerald, Becker, Lore, Irmler, Martin, Dudek, Michael, Janzen, Jakob, Goffin, Eric, Gosens, Reinoud, Knolle, Percy, Pirotte, Bernard, Stoeger, Tobias, Beckers, Johannes, Wagner, Darcy, Singh, Indrabahadur, Theis, Fabian J., de Angelis, Martin Hrabé, O’Connor, Tracy O, Tacke, Frank, Boutros, Michael, Dejardin, Emmanuel, Eickelberg, Oliver, Schiller, Herbert B., Königshoff, Melanie, Heikenwalder, Mathias, Yildirim, Ali Önder
Publicado 2020

The arginine methyltransferase PRMT7 promotes extravasation of monocytes resulting in tissue injury in COPD

por Günes Günsel, Gizem, Conlon, Thomas M., Jeridi, Aicha, Kim, Rinho, Ertüz, Zeynep, Lang, Niklas J., Ansari, Meshal, Novikova, Mariia, Jiang, Dongsheng, Strunz, Maximilian, Gaianova, Mariia, Hollauer, Christine, Gabriel, Christina, Angelidis, Ilias, Doll, Sebastian, Pestoni, Jeanine C., Edelmann, Stephanie L., Kohlhepp, Marlene Sophia, Guillot, Adrien, Bassler, Kevin, Van Eeckhoutte, Hannelore P., Kayalar, Özgecan, Konyalilar, Nur, Kanashova, Tamara, Rodius, Sophie, Ballester-López, Carolina, Genes Robles, Carlos M., Smirnova, Natalia, Rehberg, Markus, Agarwal, Charu, Krikki, Ioanna, Piavaux, Benoit, Verleden, Stijn E., Vanaudenaerde, Bart, Königshoff, Melanie, Dittmar, Gunnar, Bracke, Ken R., Schultze, Joachim L., Watz, Henrik, Eickelberg, Oliver, Stoeger, Tobias, Burgstaller, Gerald, Tacke, Frank, Heissmeyer, Vigo, Rinkevich, Yuval, Bayram, Hasan, Schiller, Herbert B., Conrad, Marcus, Schneider, Robert, Yildirim, Ali Önder
Publicado 2022