Monobodies as tool biologics for accelerating target validation and druggable site discovery

por Akkapeddi, Padma, Teng, Kai Wen, Koide, Shohei
Publicado 2021

Monobodies and other synthetic binding proteins for expanding protein science

por Sha, Fern, Salzman, Gabriel, Gupta, Ankit, Koide, Shohei
Publicado 2017

Proof of dual-topology architecture of Fluc F(-) channels with monobody blockers

por Stockbridge, Randy B., Koide, Akiko, Miller, Christopher, Koide, Shohei
Publicado 2014

Targeted rescue of cancer-associated IDH1 mutant activity using an engineered synthetic antibody

por Rizk, Shahir S., Mukherjee, Somnath, Koide, Akiko, Koide, Shohei, Kossiakoff, Anthony A.
Publicado 2017

Specific and direct modulation of the interaction between adhesion GPCR GPR56/ADGRG1 and tissue transglutaminase 2 using synthetic ligands

por Salzman, Gabriel S., Zhang, Shu, Fernandez, Celia G., Araç, Demet, Koide, Shohei
Publicado 2020

Atomic structure of the eukaryotic intramembrane Ras methyltransferase ICMT

por Diver, Melinda M., Pedi, Leanne, Koide, Akiko, Koide, Shohei, Long, Stephen B.
Publicado 2018

Monobody Inhibitor Selective to the Phosphatase Domain of SHP2 and its Use as a Probe for Quantifying SHP2 Allosteric Regulation

por Sha, Fern, Kurosawa, Kohei, Glasser, Eliezra, Ketavarapu, Gayatri, Albazzaz, Samara, Koide, Akiko, Koide, Shohei
Publicado 2023

ETO family protein Mtgr1 mediates Prdm14 functions in stem cell maintenance and primordial germ cell formation

por Nady, Nataliya, Gupta, Ankit, Ma, Ziyang, Swigut, Tomek, Koide, Akiko, Koide, Shohei, Wysocka, Joanna
Publicado 2015

Zinc binding alters the conformational dynamics and drives the transport cycle of the cation diffusion facilitator YiiP

por Lopez-Redondo, Maria, Fan, Shujie, Koide, Akiko, Koide, Shohei, Beckstein, Oliver, Stokes, David L.
Publicado 2021

Crystal structures of a double-barrelled fluoride ion channel

por Stockbridge, Randy B., Kolmakova-Partensky, Ludmila, Shane, Tania, Koide, Akiko, Koide, Shohei, Miller, Christopher, Newstead, Simon
Publicado 2015

sNASP and ASF1A function through both competitive and compatible modes of histone binding

por Bowman, Andrew, Koide, Akiko, Goodman, Jay S., Colling, Meaghan E., Zinne, Daria, Koide, Shohei, Ladurner, Andreas G.
Publicado 2017

Crystal structures of bacterial small multidrug resistance transporter EmrE in complex with structurally diverse substrates

por Kermani, Ali A, Burata, Olive E, Koff, B Ben, Koide, Akiko, Koide, Shohei, Stockbridge, Randy B
Publicado 2022

Multiplex bead binding assays using off-the-shelf components and common flow cytometers

por Hattori, Takamitsu, Koide, Akiko, Panchenko, Tatyana, Romero, Larizbeth A., Teng, Kai Wen, Corrado, Alexis D., Koide, Shohei
Publicado 2021

Mutations in the α4-α5 allosteric lobe of RAS do not significantly impair RAS signaling or self-association

por Whaby, Michael, Wallon, Lauren, Mazzei, Megan, Khan, Imran, Teng, Kai Wen, Koide, Shohei, O’Bryan, John P.
Publicado 2022

Selective Targeting of SH2 Domain–Phosphotyrosine Interactions of Src Family Tyrosine Kinases with Monobodies

por Kükenshöner, Tim, Schmit, Nadine Eliane, Bouda, Emilie, Sha, Fern, Pojer, Florence, Koide, Akiko, Seeliger, Markus, Koide, Shohei, Hantschel, Oliver
Publicado 2017

Broad-Spectrum Proteome Editing with an Engineered Bacterial Ubiquitin Ligase Mimic

por Ludwicki, Morgan B., Li, Jiahe, Stephens, Erin A., Roberts, Richard W., Koide, Shohei, Hammond, Paula T., DeLisa, Matthew P.
Publicado 2019

The ACE2-binding interface of SARS-CoV-2 Spike inherently deflects immune recognition

por Hattori, Takamitsu, Koide, Akiko, Panchenko, Tatyana, Romero, Larizbeth A., Teng, Kai Wen, Tada, Takuya, Landau, Nathaniel R., Koide, Shohei
Publicado 2020

Mechanism of disease and therapeutic rescue of Dok7 congenital myasthenia

por Oury, Julien, Zhang, Wei, Leloup, Nadia, Koide, Akiko, Corrado, Alexis D., Ketavarapu, Gayatri, Hattori, Takamitsu, Koide, Shohei, Burden, Steven J.
Publicado 2021

Creating MHC-Restricted Neoantigens with Covalent Inhibitors That Can Be Targeted by Immune Therapy

por Hattori, Takamitsu, Maso, Lorenzo, Araki, Kiyomi Y., Koide, Akiko, Hayman, James, Akkapeddi, Padma, Bang, Injin, Neel, Benjamin G., Koide, Shohei
Publicado 2023

Structural basis for the reaction cycle of DASS dicarboxylate transporters

por Sauer, David B, Trebesch, Noah, Marden, Jennifer J, Cocco, Nicolette, Song, Jinmei, Koide, Akiko, Koide, Shohei, Tajkhorshid, Emad, Wang, Da-Neng
Publicado 2020