Roles of metalloproteinase-3 and aggrecanase 1 and 2 in aggrecan cleavage during human meniscus degeneration

por Ishihara, Gintaro, Kojima, Toshihisa, Saito, Yoshimichi, Ishiguro, Naoki
Publicado 2009

Hyaluronan Inhibits Tlr-4-Dependent RANKL Expression in Human Rheumatoid Arthritis Synovial Fibroblasts

por Watanabe, Tatsuo, Takahashi, Nobunori, Hirabara, Shinya, Ishiguro, Naoki, Kojima, Toshihisa
Publicado 2016

Protective effect of geranylgeranylacetone, an inducer of heat shock protein 70, against drug-induced lung injury/fibrosis in an animal model

por Fujibayashi, Takayoshi, Hashimoto, Naozumi, Jijiwa, Mayumi, Hasegawa, Yoshinori, Kojima, Toshihisa, Ishiguro, Naoki
Publicado 2009

Hyaluronan Oligosaccharides Induce MMP-1 and -3 via Transcriptional Activation of NF-κB and p38 MAPK in Rheumatoid Synovial Fibroblasts

por Hanabayashi, Masahiro, Takahashi, Nobunori, Sobue, Yasumori, Hirabara, Shinya, Ishiguro, Naoki, Kojima, Toshihisa
Publicado 2016

Predictors of denosumab efficacy in treating osteoporosis in patients with rheumatoid arthritis: a Japanese multicenter study

por Hattori, Kyosuke, Hirano, Yuji, Kanayama, Yasuhide, Takahashi, Nobunori, Ishiguro, Naoki, Kojima, Toshihisa
Publicado 2019

Prediction of progression of damage to articular cartilage 2 years after anterior cruciate ligament reconstruction: use of aggrecan and type II collagen biomarkers in a retrospecti...

por Sobue, Yasumori, Kojima, Toshihisa, Kurokouchi, Kazutoshi, Takahashi, Shigeo, Yoshida, Hiroaki, Poole, Robin, Ishiguro, Naoki
Publicado 2017

Hyaluronan promotes TRPV4-induced chondrogenesis in ATDC5 cells

por Ogawa, Yoshikazu, Takahashi, Nobunori, Takemoto, Toki, Nishiume, Tsuyoshi, Suzuki, Mochihito, Ishiguro, Naoki, Kojima, Toshihisa
Publicado 2019

Computed tomography evaluation of the periacetabular gap of a porous tantalum acetabular component

por Asai, Shuji, Sobue, Yasumori, Asai, Nobuyuki, Takahashi, Nobunori, Watanabe, Tatsuo, Matsumoto, Takuya, Ishiguro, Naoki, Kojima, Toshihisa
Publicado 2019

Hyaluronan suppresses enhanced cathepsin K expression via activation of NF-κB with mechanical stress loading in a human chondrocytic HCS-2/8 cells

por Suzuki, Mochihito, Takahashi, Nobunori, Sobue, Yasumori, Ohashi, Yoshifumi, Kishimoto, Kenji, Hattori, Kyosuke, Ishiguro, Naoki, Kojima, Toshihisa
Publicado 2020

Usefulness of T2*-weighted MRI in the detection of adnexal torsion

por Kawai, Nobuyuki, Kato, Hiroki, Kanematsu, Masayuki, Kawaguchi, Shimpei, Kojima, Toshihisa, Furui, Tatsuro, Morishige, Ken-ichirou, Matsuo, Masayuki
Publicado 2016

Metabolic reprogramming in chondrocytes to promote mitochondrial respiration reduces downstream features of osteoarthritis

por Ohashi, Yoshifumi, Takahashi, Nobunori, Terabe, Kenya, Tsuchiya, Saho, Kojima, Toshihisa, Knudson, Cheryl B., Knudson, Warren, Imagama, Shiro
Publicado 2021

Respiratory mechanics measured by forced oscillation technique in rheumatoid arthritis-related pulmonary abnormalities: frequency-dependence, heterogeneity and effects of smoking

por Sokai, Risa, Ito, Satoru, Iwano, Shingo, Uchida, Akemi, Aso, Hiromichi, Kondo, Masashi, Ishiguro, Naoki, Kojima, Toshihisa, Hasegawa, Yoshinori
Publicado 2016

Activation of transient receptor potential vanilloid 4 protects articular cartilage against inflammatory responses via CaMKK/AMPK/NF-κB signaling pathway

por Hattori, Kyosuke, Takahashi, Nobunori, Terabe, Kenya, Ohashi, Yoshifumi, Kishimoto, Kenji, Yokota, Yutaka, Suzuki, Mochihito, Kojima, Toshihisa, Imagama, Shiro
Publicado 2021

Changes in perioperative C-reactive protein levels in patients with rheumatoid arthritis undergoing total knee arthroplasty in the biologic era

por Kishimoto, Kenji, Asai, Shuji, Takahashi, Nobunori, Terabe, Kenya, Sobue, Yasumori, Nishiume, Tsuyoshi, Suzuki, Mochihito, Ishiguro, Naoki, Kojima, Toshihisa
Publicado 2022

A Fatal Case of Relapsing Pneumonia Caused by Legionella pneumophila in a Patient with Rheumatoid Arthritis After Two Injections of Adalimumab

por Hayashi, Masatoshi, Kuraishi, Hiroshi, Masubuchi, Takeshi, Furihata, Kaneyuki, Aida, Yuka, Kobayakawa, Tomonori, Deguchi, Masao, Kojima, Toshihisa, Ishiguro, Naoki, Kanamono, Toshihisa
Publicado 2013

Soluble Siglec-9 suppresses arthritis in a collagen-induced arthritis mouse model and inhibits M1 activation of RAW264.7 macrophages

por Matsumoto, Takuya, Takahashi, Nobunori, Kojima, Toshihisa, Yoshioka, Yutaka, Ishikawa, Jun, Furukawa, Koichi, Ono, Kenji, Sawada, Makoto, Ishiguro, Naoki, Yamamoto, Akihito
Publicado 2016

Pneumococcal polyarticular septic arthritis after a single infusion of infliximab in a rheumatoid arthritis patient: a case report

por Hayashi, Masatoshi, Kojima, Toshihisa, Funahashi, Koji, Kato, Daizo, Matsubara, Hiroyuki, Shioura, Tomone, Kanayama, Yasuhide, Hirano, Yuji, Deguchi, Masao, Kanamono, Toshihisa, Ishiguro, Naoki
Publicado 2012

Inhibition of CD44 intracellular domain production suppresses bovine articular chondrocyte de-differentiation induced by excessive mechanical stress loading

por Sobue, Yasumori, Takahashi, Nobunori, Ohashi, Yoshifumi, Suzuki, Mochihito, Nishiume, Tsuyoshi, Kobayakawa, Tomonori, Terabe, Kenya, Knudson, Warren, Knudson, Cheryl, Ishiguro, Naoki, Kojima, Toshihisa
Publicado 2019

Relationship between rheumatoid arthritis and locomotive syndrome: validation of the 25-question Geriatric Locomotive Function Scale in patients with rheumatoid arthritis

por Sobue, Yasumori, Kojima, Toshihisa, Funahashi, Koji, Okui, Nobuyuki, Mizuno, Masanori, Takahashi, Nobunori, Asai, Shuji, Asai, Nobuyuki, Matsumoto, Takuya, Nishiume, Tsuyoshi, Suzuki, Mochihito, Ishiguro, Naoki
Publicado 2019

Successful Perioperative Combination of High-Dose FVIII Therapy Followed by Emicizumab in a Patient with Hemophilia A with Inhibitors

por Okamoto, Shuichi, Suzuki, Nobuaki, Suzuki, Atsuo, Suzuki, Sachiko, Tamura, Shogo, Suzuki, Mochihito, Takahashi, Nobunori, Kojima, Toshihisa, Kanematsu, Takeshi, Kojima, Tetsuhito, Kiyoi, Hitoshi, Ishiguro, Naoki, Matsushita, Tadashi
Publicado 2019