Dynamic interaction of local and transhemispheric networks is necessary for progressive intensification of hippocampal seizures

por Berglind, Fredrik, Andersson, My, Kokaia, Merab
Publicado 2018

Directly Converted Human Fibroblasts Mature to Neurons and Show Long-Term Survival in Adult Rodent Hippocampus

por Avaliani, Natalia, Pfisterer, Ulrich, Heuer, Andreas, Parmar, Malin, Kokaia, Merab, Andersson, My
Publicado 2017

Preserved Function of Afferent Parvalbumin-Positive Perisomatic Inhibitory Synapses of Dentate Granule Cells in Rapidly Kindled Mice

por Hansen, Marita G., Ledri, Litsa N., Kirik, Deniz, Kokaia, Merab, Ledri, Marco
Publicado 2018

VEGF Receptor-2 (Flk-1) Overexpression in Mice Counteracts Focal Epileptic Seizures

por Nikitidou, Litsa, Kanter-Schlifke, Irene, Dhondt, Joke, Carmeliet, Peter, Lambrechts, Diether, Kokaia, Mérab
Publicado 2012

Altered Chloride Homeostasis Decreases the Action Potential Threshold and Increases Hyperexcitability in Hippocampal Neurons

por Sørensen, Andreas T., Ledri, Marco, Melis, Miriam, Nikitidou Ledri, Litsa, Andersson, My, Kokaia, Merab
Publicado 2018

Editorial: Gene Therapy in the CNS – Progress and Prospects for Novel Therapies

por Ledri, Marco, Sørensen, Andreas T., Kokaia, Merab, Woldbye, David P. D., Gøtzsche, Casper R.
Publicado 2021

Human Stem Cell-Derived GABAergic Interneurons Establish Efferent Synapses onto Host Neurons in Rat Epileptic Hippocampus and Inhibit Spontaneous Recurrent Seizures

por Waloschková, Eliška, Gonzalez-Ramos, Ana, Mikroulis, Apostolos, Kudláček, Jan, Andersson, My, Ledri, Marco, Kokaia, Merab
Publicado 2021

Long-Term Effects of Myoinositol on Behavioural Seizures and Biochemical Changes Evoked by Kainic Acid Induced Epileptogenesis

por Tsverava, Lia, Kandashvili, Manana, Margvelani, Giorgi, Lortkipanidze, Tamar, Gamkrelidze, Georgi, Lepsveridze, Eka, Kokaia, Merab, Solomonia, Revaz
Publicado 2019

Lipid mediator n‐3 docosapentaenoic acid‐derived protectin D1 enhances synaptic inhibition of hippocampal principal neurons by interaction with a G‐protein‐coupled receptor

por Mikroulis, Apostolos, Ledri, Marco, Ruffolo, Gabriele, Palma, Eleonora, Sperk, Günther, Dalli, Jesmond, Vezzani, Annamaria, Kokaia, Merab
Publicado 2022

Disease Modification by Combinatorial Single Vector Gene Therapy: A Preclinical Translational Study in Epilepsy

por Melin, Esbjörn, Nanobashvili, Avtandil, Avdic, Una, Gøtzsche, Casper R., Andersson, My, Woldbye, David P.D., Kokaia, Merab
Publicado 2019

Human stem cell-derived GABAergic neurons functionally integrate into human neuronal networks

por Gonzalez-Ramos, Ana, Waloschková, Eliška, Mikroulis, Apostolos, Kokaia, Zaal, Bengzon, Johan, Ledri, Marco, Andersson, My, Kokaia, Merab
Publicado 2021

Functional Integration of Grafted Neural Stem Cell-Derived Dopaminergic Neurons Monitored by Optogenetics in an In Vitro Parkinson Model

por Tønnesen, Jan, Parish, Clare L., Sørensen, Andreas T., Andersson, Angelica, Lundberg, Cecilia, Deisseroth, Karl, Arenas, Ernest, Lindvall, Olle, Kokaia, Merab
Publicado 2011

Myo-Inositol Limits Kainic Acid-Induced Epileptogenesis in Rats

por Kandashvili, Manana, Gamkrelidze, Georgi, Tsverava, Lia, Lordkipanidze, Tamar, Lepsveridze, Eka, Lagani, Vincenzo, Burjanadze, Maia, Dashniani, Manana, Kokaia, Merab, Solomonia, Revaz
Publicado 2022

Inhibition of epileptiform activity by neuropeptide Y in brain tissue from drug-resistant temporal lobe epilepsy patients

por Wickham, Jenny, Ledri, Marco, Bengzon, Johan, Jespersen, Bo, Pinborg, Lars H., Englund, Elisabet, Woldbye, David P. D., Andersson, My, Kokaia, Merab
Publicado 2019

Transcription factor-based direct conversion of human fibroblasts to functional astrocytes

por Quist, Ella, Trovato, Francesco, Avaliani, Natalia, Zetterdahl, Oskar G., Gonzalez-Ramos, Ana, Hansen, Marita G., Kokaia, Merab, Canals, Isaac, Ahlenius, Henrik
Publicado 2022

Gene Therapy Vector Encoding Neuropeptide Y and Its Receptor Y2 for Future Treatment of Epilepsy: Preclinical Data in Rats

por Szczygieł, Julia Alicja, Danielsen, Kira Iben, Melin, Esbjörn, Rosenkranz, Søren Hofman, Pankratova, Stanislava, Ericsson, Annika, Agerman, Karin, Kokaia, Merab, Woldbye, David Paul Drucker
Publicado 2020

Optogenetic control of human neurons in organotypic brain cultures

por Andersson, My, Avaliani, Natalia, Svensson, Andreas, Wickham, Jenny, Pinborg, Lars H., Jespersen, Bo, Christiansen, Søren H., Bengzon, Johan, Woldbye, David P.D., Kokaia, Merab
Publicado 2016

GDNF Increases Inhibitory Synaptic Drive on Principal Neurons in the Hippocampus via Activation of the Ret Pathway

por Mikroulis, Apostolos, Waloschková, Eliška, Bengzon, Johan, Woldbye, David, Pinborg, Lars H., Jespersen, Bo, Avila, Anna Sanchez, Laszlo, Zsofia I., Henstridge, Christopher, Ledri, Marco, Kokaia, Merab
Publicado 2022

Combinatorial gene therapy for epilepsy: Gene sequence positioning and AAV serotype influence expression and inhibitory effect on seizures

por Melin, Esbjörn, Andersson, My, Gøtzsche, Casper R., Wickham, Jenny, Huang, Yuzhe, Szczygiel, Julia Alicja, Boender, Arnie, Christiansen, Søren H., Pinborg, Lars, Woldbye, David P. D., Kokaia, Merab
Publicado 2023

Leaky Optoelectrical Fiber for Optogenetic Stimulation and Electrochemical Detection of Dopamine Exocytosis from Human Dopaminergic Neurons

por Vasudevan, Shashank, Kajtez, Janko, Bunea, Ada‐Ioana, Gonzalez‐Ramos, Ana, Ramos‐Moreno, Tania, Heiskanen, Arto, Kokaia, Merab, Larsen, Niels B., Martínez‐Serrano, Alberto, Keller, Stephan S., Emnéus, Jenny
Publicado 2019