Structural Modeling of TRPA1 Ion Channel—Determination of the Binding Site for Antagonists

por Gawalska, Alicja, Kołaczkowski, Marcin, Bucki, Adam
Publicado 2022

Idalopirdine – a small molecule antagonist of 5-HT(6) with therapeutic potential against obesity

por Dudek, Magdalena, Marcinkowska, Monika, Bucki, Adam, Olczyk, Adrian, Kołaczkowski, Marcin
Publicado 2015

Study on a Three-Step Rapid Assembly of Zolpidem and Its Fluorinated Analogues Employing Microwave-Assisted Chemistry

por Fajkis, Nikola, Marcinkowska, Monika, Gryzło, Beata, Krupa, Anna, Kolaczkowski, Marcin
Publicado 2020

Antipsychotic, antidepressant, and cognitive-impairment properties of antipsychotics: rat profile and implications for behavioral and psychological symptoms of dementia

por Kołaczkowski, Marcin, Mierzejewski, Paweł, Bienkowski, Przemyslaw, Wesołowska, Anna, Newman-Tancredi, Adrian
Publicado 2014

Metabolic and Cardiovascular Benefits and Risks of EMD386088—A 5-HT(6) Receptor Partial Agonist and Dopamine Transporter Inhibitor

por Kotańska, Magdalena, Śniecikowska, Joanna, Jastrzębska-Więsek, Magdalena, Kołaczkowski, Marcin, Pytka, Karolina
Publicado 2017

Idalopirdine, a selective 5-HT(6) receptor antagonist, reduces food intake and body weight in a model of excessive eating

por Kotańska, Magdalena, Lustyk, Klaudia, Bucki, Adam, Marcinkowska, Monika, Śniecikowska, Joanna, Kołaczkowski, Marcin
Publicado 2018

Management of Dementia-Related Psychosis, Agitation and Aggression: A Review of the Pharmacology and Clinical Effects of Potential Drug Candidates

por Marcinkowska, Monika, Śniecikowska, Joanna, Fajkis, Nikola, Paśko, Paweł, Franczyk, Weronika, Kołaczkowski, Marcin
Publicado 2020

Metabolic carbonyl reduction of anthracyclines — role in cardiotoxicity and cancer resistance. Reducing enzymes as putative targets for novel cardioprotective and chemosensitizing...

por Piska, Kamil, Koczurkiewicz, Paulina, Bucki, Adam, Wójcik-Pszczoła, Katarzyna, Kołaczkowski, Marcin, Pękala, Elżbieta
Publicado 2017

Novel serotonin 5-HT(2A) receptor antagonists derived from 4-phenylcyclohexane-5-spiro-and 5-methyl-5-phenyl-hydantoin, for use as potential antiplatelet agents

por Czopek, Anna, Kubacka, Monika, Bucki, Adam, Siwek, Agata, Filipek, Barbara, Pawłowski, Maciej, Kołaczkowski, Marcin
Publicado 2021

Metabolic and cardiovascular benefits and risks of 4-hydroxy guanabenz hydrochloride: α(2)-adrenoceptor and trace amine-associated receptor 1 ligand

por Kotańska, Magdalena, Marcinkowska, Monika, Kuder, Kamil J., Walczak, Maria, Bednarski, Marek, Siwek, Agata, Kołaczkowski, Marcin
Publicado 2023

ADN-1184, a monoaminergic ligand with 5-HT(6/7) receptor antagonist action, exhibits activity in animal models of anxiety

por Partyka, Anna, Wasik, Anna, Jastrzębska-Więsek, Magdalena, Mierzejewski, Paweł, Bieńkowski, Przemysław, Kołaczkowski, Marcin, Wesołowska, Anna
Publicado 2016

Potential Anti-Amnesic Activity of a Novel Multimodal Derivative of Salicylamide, JJGW08, in Mice

por Żmudzka, Elżbieta, Lustyk, Klaudia, Sałaciak, Kinga, Siwek, Agata, Jaśkowska, Jolanta, Kołaczkowski, Marcin, Sapa, Jacek, Pytka, Karolina
Publicado 2023

Synthesis, In Vitro, and Computational Studies of PTP1B Phosphatase Inhibitors Based on Oxovanadium(IV) and Dioxovanadium(V) Complexes

por Kostrzewa, Tomasz, Jończyk, Jakub, Drzeżdżon, Joanna, Jacewicz, Dagmara, Górska-Ponikowska, Magdalena, Kołaczkowski, Marcin, Kuban-Jankowska, Alicja
Publicado 2022

In Silico and In Vitro Assessment of Carbonyl Reductase 1 Inhibition Using ASP9521—A Potent Aldo-Keto Reductase 1C3 Inhibitor with the Potential to Support Anticancer Therapy Using...

por Jamrozik, Marek, Piska, Kamil, Bucki, Adam, Koczurkiewicz-Adamczyk, Paulina, Sapa, Michał, Władyka, Benedykt, Pękala, Elżbieta, Kołaczkowski, Marcin
Publicado 2023

Novel Multimodal Salicylamide Derivative with Antidepressant-like, Anxiolytic-like, Antipsychotic-like, and Anti-Amnesic Activity in Mice

por Żmudzka, Elżbieta, Lustyk, Klaudia, Głuch-Lutwin, Monika, Wolak, Małgorzata, Jaśkowska, Jolanta, Kołaczkowski, Marcin, Sapa, Jacek, Pytka, Karolina
Publicado 2023

Study of a mechanism responsible for potential antidepressant activity of EMD 386088, a 5-HT(6) partial agonist in rats

por Jastrzębska-Więsek, Magdalena, Siwek, Agata, Partyka, Anna, Antkiewicz-Michaluk, Lucyna, Michaluk, Jerzy, Romańska, Irena, Kołaczkowski, Marcin, Wesołowska, Anna
Publicado 2016

The selective 5-HT(1A) receptor biased agonists, F15599 and F13714, show antidepressant-like properties after a single administration in the mouse model of unpredictable chronic mi...

por Głuch-Lutwin, Monika, Sałaciak, Kinga, Gawalska, Alicja, Jamrozik, Marek, Sniecikowska, Joanna, Newman-Tancredi, Adrian, Kołaczkowski, Marcin, Pytka, Karolina
Publicado 2021

Novel Arylpiperazine Derivatives of Salicylamide with α(1)-Adrenolytic Properties Showed Antiarrhythmic and Hypotensive Properties in Rats

por Żmudzka, Elżbieta, Lustyk, Klaudia, Siwek, Agata, Wolak, Małgorzata, Gałuszka, Adam, Jaśkowska, Jolanta, Kołaczkowski, Marcin, Sapa, Jacek, Pytka, Karolina
Publicado 2022

2-(4-Fluorophenyl)-1H-benzo[d]imidazole as a Promising Template for the Development of Metabolically Robust, α1β2γ2GABA-A Receptor-Positive Allosteric Modulators

por Marcinkowska, Monika, Fajkis-Zajączkowska, Nikola, Szafrańska, Katarzyna, Jończyk, Jakub, Siwek, Agata, Mordyl, Barbara, Karcz, Tadeusz, Latacz, Gniewomir, Kolaczkowski, Marcin
Publicado 2023

Novel and effective synthesis protocol of AgNPs functionalized using L-cysteine as a potential drug carrier

por Wojnicki, Marek, Luty-Błocho, Magdalena, Kotańska, Magdalena, Wytrwal, Magdalena, Tokarski, Tomasz, Krupa, Anna, Kołaczkowski, Marcin, Bucki, Adam, Kobielusz, Marcin
Publicado 2017