IL-33 Mediates Lung Inflammation by the IL-6-Type Cytokine Oncostatin M

por Botelho, Fernando, Dubey, Anisha, Ayaub, Ehab A., Park, Rex, Yip, Ashley, Humbles, Allison, Kolbeck, Roland, Richards, Carl D.
Publicado 2020

Complement C5a induces PD-L1 expression and acts in synergy with LPS through Erk1/2 and JNK signaling pathways

por An, Ling-Ling, Gorman, Jacob V., Stephens, Geoffrey, Swerdlow, Bonnie, Warrener, Paul, Bonnell, Jessica, Mustelin, Tomas, Fung, Michael, Kolbeck, Roland
Publicado 2016

Novel mechanisms of action contributing to benralizumab's potent anti-eosinophilic activity

por Dagher, Rania, Kumar, Varsha, Copenhaver, Alan M., Gallagher, Sandra, Ghaedi, Mahboobe, Boyd, Jonathan, Newbold, Paul, Humbles, Alison A., Kolbeck, Roland
Publicado 2022

Plasmacytoid Dendritic Cells Are Largely Dispensable for the Pathogenesis of Experimental Inflammatory Bowel Disease

por Sawai, Catherine M., Serpas, Lee, Neto, Antonio Galvao, Jang, Geunhyo, Rashidfarrokhi, Ali, Kolbeck, Roland, Sanjuan, Miguel A., Reizis, Boris, Sisirak, Vanja
Publicado 2018

B7-H7 (HHLA2) inhibits T-cell activation and proliferation in the presence of TCR and CD28 signaling

por Rieder, Sadiye Amcaoglu, Wang, Jingya, White, Natalie, Qadri, Ariful, Menard, Catherine, Stephens, Geoffrey, Karnell, Jodi L., Rudd, Christopher E., Kolbeck, Roland
Publicado 2020

Early, transient depletion of plasmacytoid dendritic cells ameliorates autoimmunity in a lupus model

por Rowland, Sarah L., Riggs, Jeffrey M., Gilfillan, Susan, Bugatti, Mattia, Vermi, William, Kolbeck, Roland, Unanue, Emil R., Sanjuan, Miguel A., Colonna, Marco
Publicado 2014

Evaluation of ultra-low input RNA sequencing for the study of human T cell transcriptome

por Wang, Jingya, Rieder, Sadiye Amcaoglu, Wu, Jincheng, Hayes, Susana, Halpin, Rebecca A., de los Reyes, Melissa, Shrestha, Yashaswi, Kolbeck, Roland, Raja, Rajiv
Publicado 2019

Distinct and common expression of receptors for inflammatory mediators in vagal nodose versus jugular capsaicin-sensitive/TRPV1-positive neurons detected by low input RNA sequencin...

por Wang, Jingya, Kollarik, Marian, Ru, Fei, Sun, Hui, McNeil, Benjamin, Dong, Xinzhong, Stephens, Geoffrey, Korolevich, Susana, Brohawn, Philip, Kolbeck, Roland, Undem, Bradley
Publicado 2017

Cigarette smoke-induced accumulation of lung dendritic cells is interleukin-1α-dependent in mice

por Botelho, Fernando M, Nikota, Jake K, Bauer, Carla MT, Morissette, Mathieu C, Iwakura, Yoichiro, Kolbeck, Roland, Finch, Donna, Humbles, Alison A, Stämpfli, Martin R
Publicado 2012

RAGE inhibits human respiratory syncytial virus syncytium formation by interfering with F-protein function

por Tian, Jane, Huang, Kelly, Krishnan, Subramaniam, Svabek, Catherine, Rowe, Daniel C., Brewah, Yambasu, Sanjuan, Miguel, Patera, Andriani C., Kolbeck, Roland, Herbst, Ronald, Sims, Gary P.
Publicado 2013

Persistence of pulmonary tertiary lymphoid tissues and anti-nuclear antibodies following cessation of cigarette smoke exposure

por Morissette, Mathieu C, Jobse, Brian N, Thayaparan, Danya, Nikota, Jake K, Shen, Pamela, Labiris, Nancy Renée, Kolbeck, Roland, Nair, Parameswaran, Humbles, Alison A, Stämpfli, Martin R
Publicado 2014

Eosinophils, basophils and type 2 immune microenvironments in COPD-affected lung tissue

por Jogdand, Prajakta, Siddhuraj, Premkumar, Mori, Michiko, Sanden, Caroline, Jönsson, Jimmie, Walls, Andrew F., Kearley, Jennifer, Humbles, Alison A., Kolbeck, Roland, Bjermer, Leif, Newbold, Paul, Erjefält, Jonas S.
Publicado 2020

Targeting p16-induced senescence prevents cigarette smoke-induced emphysema by promoting IGF1/Akt1 signaling in mice

por Cottage, Christopher T., Peterson, Norman, Kearley, Jennifer, Berlin, Aaron, Xiong, Ximing, Huntley, Anna, Zhao, Weiguang, Brown, Charles, Migneault, Annik, Zerrouki, Kamelia, Criner, Gerald, Kolbeck, Roland, Connor, Jane, Lemaire, Raphael
Publicado 2019

Opposing Roles of Membrane and Soluble Forms of the Receptor for Advanced Glycation End Products in Primary Respiratory Syncytial Virus Infection

por Miller, Allison L., Sims, Gary P., Brewah, Yambasu A., Rebelatto, Marlon C., Kearley, Jennifer, Benjamin, Ebony, Keller, Ashley E., Brohawn, Philip, Herbst, Ronald, Coyle, Anthony J., Humbles, Alison A., Kolbeck, Roland
Publicado 2012

Immunosuppression reduces rAAV2.5T neutralizing antibodies that limit efficacy following repeat dosing to ferret lungs

por Tang, Yinghua, Fakhari, Shahab, Huntemann, Eric D., Feng, Zehua, Wu, Peipei, Feng, William Y., Lei, Junying, Yuan, Feng, Excoffon, Katherine J., Wang, Kai, Limberis, Maria P., Kolbeck, Roland, Yan, Ziying, Engelhardt, John F.
Publicado 2023

Activated Human T Cells, B Cells, and Monocytes Produce Brain-derived Neurotrophic Factor In Vitro and in Inflammatory Brain Lesions: A Neuroprotective Role of Inflammation?

por Kerschensteiner, Martin, Gallmeier, Eike, Behrens, Lüder, Leal, Vivian Vargas, Misgeld, Thomas, Klinkert, Wolfgang E.F., Kolbeck, Roland, Hoppe, Edmund, Oropeza-Wekerle, Rosa-Laura, Bartke, Ilse, Stadelmann, Christine, Lassmann, Hans, Wekerle, Hartmut, Hohlfeld, Reinhard
Publicado 1999

Low-density granulocytes activate T cells and demonstrate a non-suppressive role in systemic lupus erythematosus

por Rahman, Saifur, Sagar, Divya, Hanna, Richard N, Lightfoot, Yaima L, Mistry, Pragnesh, Smith, Carolyne K, Manna, Zerai, Hasni, Sarfaraz, Siegel, Richard M, Sanjuan, Miguel A, Kolbeck, Roland, Kaplan, Mariana J, Casey, Kerry A
Publicado 2019

IL-33-ST2 axis regulates myeloid cell differentiation and activation enabling effective club cell regeneration

por Dagher, Rania, Copenhaver, Alan M., Besnard, Valerie, Berlin, Aaron, Hamidi, Fatima, Maret, Marielle, Wang, Jingya, Qu, Xiaotao, Shrestha, Yashaswi, Wu, Jincheng, Gautier, Gregory, Raja, Rajiv, Aubier, Michel, Kolbeck, Roland, Humbles, Alison A., Pretolani, Marina
Publicado 2020

SLE Plasma Profiling Identifies Unique Signatures of Lupus Nephritis and Discoid Lupus

por Smith, Michael A., Henault, Jill, Karnell, Jodi L., Parker, Melissa L., Riggs, Jeffrey M., Sinibaldi, Dominic, Taylor, Devon K., Ettinger, Rachel, Grant, Ethan P., Sanjuan, Miguel A., Kolbeck, Roland, Petri, Michelle A., Casey, Kerry A.
Publicado 2019

Proteomic profiling of serum identifies a molecular signature that correlates with clinical outcomes in COPD

por Dagher, Rania, Fogel, Paul, Wang, Jingya, Soussan, David, Chiang, Chia-Chien, Kearley, Jennifer, Muthas, Daniel, Taillé, Camille, Berger, Patrick, Bourdin, Arnaud, Chenivesse, Cécile, Leroy, Sylvie, Anderson, Gary, Humbles, Alison A., Aubier, Michel, Kolbeck, Roland, Pretolani, Marina
Publicado 2022