The convergent roles of NF-κB and ER stress in sunitinib-mediated expression of pro-tumorigenic cytokines and refractory phenotype in renal cell carcinoma

por Makhov, Peter, Naito, Sei, Haifler, Miki, Kutikov, Alexander, Boumber, Yanis, Uzzo, Robert G., Kolenko, Vladimir M.
Publicado 2018

Cadmium down-regulates expression of XIAP at the post-transcriptional level in prostate cancer cells through an NF-κB-independent, proteasome-mediated mechanism

por Golovine, Konstantin, Makhov, Peter, Uzzo, Robert G, Kutikov, Alexander, Kaplan, David J, Fox, Eric, Kolenko, Vladimir M
Publicado 2010

Poly(ADP)-Ribosylation Inhibition: A Promising Approach for Clear Cell Renal Cell Carcinoma Therapy

por Karpova, Yaroslava, Guo, Danping, Makhov, Peter, Haines, Adam M., Markov, Dmitriy A., Kolenko, Vladimir, Tulin, Alexei V.
Publicado 2021

LDL cholesterol counteracts the antitumour effect of tyrosine kinase inhibitors against renal cell carcinoma

por Naito, Sei, Makhov, Peter, Astsaturov, Igor, Golovine, Konstantin, Tulin, Alexei, Kutikov, Alexander, Uzzo, Robert G, Kolenko, Vladimir M
Publicado 2017

CRISPR/Cas9 genome-wide loss-of-function screening identifies druggable cellular factors involved in sunitinib resistance in renal cell carcinoma

por Makhov, Peter, Sohn, Ji A., Serebriiskii, Ilya G., Fazliyeva, Rushaniya, Khazak, Vladimir, Boumber, Yanis, Uzzo, Robert G., Kolenko, Vladimir M.
Publicado 2020

Minor grove binding ligands disrupt PARP-1 activation pathways

por Kirsanov, Kirill I., Kotova, Elena, Makhov, Petr, Golovine, Konstantin, Lesovaya, Ekaterina A., Kolenko, Vladimir M., Yakubovskaya, Marianna G., Tulin, Alexei V.
Publicado 2014

Non-NAD-Like poly(ADP-Ribose) Polymerase-1 Inhibitors effectively Eliminate Cancer in vivo

por Thomas, Colin, Ji, Yingbiao, Lodhi, Niraj, Kotova, Elena, Pinnola, Aaron Dan, Golovine, Konstantin, Makhov, Peter, Pechenkina, Kate, Kolenko, Vladimir, Tulin, Alexei V.
Publicado 2016

Acetyl-CoA Counteracts the Inhibitory Effect of Antiandrogens on Androgen Receptor Signaling in Prostate Cancer Cells

por Makhov, Peter, Fazliyeva, Rushaniya, Tufano, Antonio, Uzzo, Robert G., Cai, Kathy Q., Serebriiskii, Ilya, Snyder, Nathaniel W., Andrews, Andrew J., Kolenko, Vladimir M.
Publicado 2022

PPP2R2A prostate cancer haploinsufficiency is associated with worse prognosis and a high vulnerability to B55α/PP2A reconstitution that triggers centrosome destabilization

por Zhao, Ziran, Kurimchak, Alison, Nikonova, Anna S., Feiser, Felicity, Wasserman, Jason S., Fowle, Holly, Varughese, Tinsa, Connors, Megan, Johnson, Katherine, Makhov, Petr, Lindskog, Cecilia, Kolenko, Vladimir M., Golemis, Erica A., Duncan, James S., Graña, Xavier
Publicado 2019

Expression of total and phospho 4EBP1 in metastatic and non-metastatic renal cell carcinoma

por Naito, Sei, Ichiyanagi, Osamu, Ito, Hiromi, Kabasawa, Takanobu, Kanno, Hidenori, Narisawa, Takafumi, Fukuhara, Hiroki, Yagi, Mayu, Kurota, Yuta, Yamagishi, Atsushi, Sakurai, Toshihiko, Nishida, Hayato, Kawazoe, Hisashi, Yamanobe, Takuya, Kato, Tomoyuki, Makhov, Peter, Kolenko, Vladimir M., Yamakawa, Mitsunori, Tsuchiya, Norihiko
Publicado 2019