Inhibition of FAK kinase activity preferentially targets cancer stem cells

por Kolev, Vihren N., Tam, Winnie F., Wright, Quentin G., McDermott, Sean P., Vidal, Christian M., Shapiro, Irina M., Xu, Qunli, Wicha, Max S., Pachter, Jonathan A., Weaver, David T.
Publicado 2017

TAK-676: A Novel Stimulator of Interferon Genes (STING) Agonist Promoting Durable IFN-dependent Antitumor Immunity in Preclinical Studies

por Carideo Cunniff, Elizabeth, Sato, Yosuke, Mai, Doanh, Appleman, Vicky A., Iwasaki, Shinji, Kolev, Vihren, Matsuda, Atsushi, Shi, Judy, Mochizuki, Michiyo, Yoshikawa, Masato, Huang, Jian, Shen, Luhua, Haridas, Satyajeet, Shinde, Vaishali, Gemski, Chris, Roberts, Emily R., Ghasemi, Omid, Bazzazi, Hojjat, Menon, Saurabh, Traore, Tary, Shi, Pu, Thelen, Tennille D., Conlon, Joseph, Abu-Yousif, Adnan O., Arendt, Christopher, Shaw, Michael H., Okaniwa, Masanori
Publicado 2022

FAK activity sustains intrinsic and acquired ovarian cancer resistance to platinum chemotherapy

por Diaz Osterman, Carlos J, Ozmadenci, Duygu, Kleinschmidt, Elizabeth G, Taylor, Kristin N, Barrie, Allison M, Jiang, Shulin, Bean, Lisa M, Sulzmaier, Florian J, Jean, Christine, Tancioni, Isabelle, Anderson, Kristen, Uryu, Sean, Cordasco, Edward A, Li, Jian, Chen, Xiao Lei, Fu, Guo, Ojalill, Marjaana, Rappu, Pekka, Heino, Jyrki, Mark, Adam M, Xu, Guorong, Fisch, Kathleen M, Kolev, Vihren N, Weaver, David T, Pachter, Jonathan A, Győrffy, Balázs, McHale, Michael T, Connolly, Denise C, Molinolo, Alfredo, Stupack, Dwayne G, Schlaepfer, David D
Publicado 2019