Abuse and dependence potential of sphingosine-1-phosphate (S1P) receptor modulators used in the treatment of multiple sclerosis: a review of literature and public data

por Schoedel, Kerri A., Kolly, Carine, Gardin, Anne, Neelakantham, Srikanth, Shakeri-Nejad, Kasra
Publicado 2021

A Pooled Analysis of Three Randomized Phase I/IIa Clinical Trials Confirms Absence of a Clinically Relevant Effect on the QTc Interval by Umibecestat

por Vormfelde, Stefan Viktor, Pezous, Nicole, Lefèvre, Gilbert, Kolly, Carine, Neumann, Ulf, Jordaan, Pierre, Ufer, Mike, Legangneux, Eric
Publicado 2020

Proliferative and Non-Proliferative Lesions of the Rat and Mouse Integument

por Mecklenburg, Lars, Kusewitt, Donna, Kolly, Carine, Treumann, Silke, Adams, E. Terence, Diegel, Kelly, Yamate, Jyoji, Kaufmann, Wolfgang, Müller, Susanne, Danilenko, Dimitry, Bradley, Alys
Publicado 2014

Pharmacological BACE1 and BACE2 inhibition induces hair depigmentation by inhibiting PMEL17 processing in mice

por Shimshek, Derya R., Jacobson, Laura H., Kolly, Carine, Zamurovic, Natasa, Balavenkatraman, Kamal Kumar, Morawiec, Laurent, Kreutzer, Robert, Schelle, Juliane, Jucker, Mathias, Bertschi, Barbara, Theil, Diethilde, Heier, Annabelle, Bigot, Karine, Beltz, Karen, Machauer, Rainer, Brzak, Irena, Perrot, Ludovic, Neumann, Ulf
Publicado 2016

Induction of hemangiosarcoma in mice after chronic treatment with S1P-modulator siponimod and its lack of relevance to rat and human

por Pognan, Francois, Mahl, J. Andreas, Papoutsi, Maria, Ledieu, David, Raccuglia, Marc, Theil, Diethilde, Voytek, Sarah B., Devine, Patrick J., Kubek-Luck, Katie, Claudio, Natalie, Cordier, Andre, Heier, Annabelle, Kolly, Carine, Hartmann, Andreas, Chibout, Salah-Dine, Bouchard, Page, Trendelenburg, Christian
Publicado 2018

LRRK2 protein levels are determined by kinase function and are crucial for kidney and lung homeostasis in mice

por Herzig, Martin C., Kolly, Carine, Persohn, Elke, Theil, Diethilde, Schweizer, Tatjana, Hafner, Thomas, Stemmelen, Christine, Troxler, Thomas J., Schmid, Peter, Danner, Simone, Schnell, Christian R., Mueller, Matthias, Kinzel, Bernd, Grevot, Armelle, Bolognani, Federico, Stirn, Martina, Kuhn, Rainer R., Kaupmann, Klemens, van der Putten, P. Herman, Rovelli, Giorgio, Shimshek, Derya R.
Publicado 2011

The BACE‐1 inhibitor CNP520 for prevention trials in Alzheimer's disease

por Neumann, Ulf, Ufer, Mike, Jacobson, Laura H, Rouzade‐Dominguez, Marie‐Laure, Huledal, Gunilla, Kolly, Carine, Lüönd, Rainer M, Machauer, Rainer, Veenstra, Siem J, Hurth, Konstanze, Rueeger, Heinrich, Tintelnot‐Blomley, Marina, Staufenbiel, Matthias, Shimshek, Derya R, Perrot, Ludovic, Frieauff, Wilfried, Dubost, Valerie, Schiller, Hilmar, Vogg, Barbara, Beltz, Karen, Avrameas, Alexandre, Kretz, Sandrine, Pezous, Nicole, Rondeau, Jean‐Michel, Beckmann, Nicolau, Hartmann, Andreas, Vormfelde, Stefan, David, Olivier J, Galli, Bruno, Ramos, Rita, Graf, Ana, Lopez Lopez, Cristina
Publicado 2018