Type I interferons act directly on CD8 T cells to allow clonal expansion and memory formation in response to viral infection

por Kolumam, Ganesh A., Thomas, Sunil, Thompson, Lucas J., Sprent, Jonathan, Murali-Krishna, Kaja
Publicado 2005

In Vivo Depletion of Lymphotoxin-Alpha Expressing Lymphocytes Inhibits Xenogeneic Graft-versus-Host-Disease

por Chiang, Eugene Y., Kolumam, Ganesh, McCutcheon, Krista M., Young, Judy, Lin, Zhonghua, Balazs, Mercedesz, Grogan, Jane L.
Publicado 2012

Automated, high-dimensional evaluation of physiological aging and resilience in outbred mice

por Chen, Zhenghao, Raj, Anil, Prateek, GV, Di Francesco, Andrea, Liu, Justin, Keyes, Brice E, Kolumam, Ganesh, Jojic, Vladimir, Freund, Adam
Publicado 2022

IL-22R Ligands IL-20, IL-22, and IL-24 Promote Wound Healing in Diabetic db/db Mice

por Kolumam, Ganesh, Wu, Xiumin, Lee, Wyne P., Hackney, Jason A., Zavala-Solorio, Jose, Gandham, Vineela, Danilenko, Dimitry M., Arora, Puneet, Wang, Xiaoting, Ouyang, Wenjun
Publicado 2017

Antibody-Mediated Activation of FGFR1 Induces FGF23 Production and Hypophosphatemia

por Wu, Ai-Luen, Feng, Bo, Chen, Mark Z., Kolumam, Ganesh, Zavala-Solorio, Jose, Wyatt, Shelby K., Gandham, Vineela D., Carano, Richard A. D., Sonoda, Junichiro
Publicado 2013

Furin-cleaved Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) Is Active and Modulates Low Density Lipoprotein Receptor and Serum Cholesterol Levels

por Lipari, Michael T., Li, Wei, Moran, Paul, Kong-Beltran, Monica, Sai, Tao, Lai, Joyce, Lin, S. Jack, Kolumam, Ganesh, Zavala-Solorio, Jose, Izrael-Tomasevic, Anita, Arnott, David, Wang, Jianyong, Peterson, Andrew S., Kirchhofer, Daniel
Publicado 2012

Inhibitory Mechanism of an Allosteric Antibody Targeting the Glucagon Receptor

por Mukund, Susmith, Shang, Yonglei, Clarke, Holly J., Madjidi, Azadeh, Corn, Jacob E., Kates, Lance, Kolumam, Ganesh, Chiang, Vicky, Luis, Elizabeth, Murray, Jeremy, Zhang, Yingnan, Hötzel, Isidro, Koth, Christopher M., Allan, Bernard B.
Publicado 2013

Intermittent fasting and caloric restriction interact with genetics to shape physiological health in mice

por Zhang, Guozhu, Deighan, Andrew, Raj, Anil, Robinson, Laura, Donato, Hannah J, Garland, Gaven, Leland, Mackenzie, Martin-McNulty, Baby, Kolumam, Ganesh A, Riegler, Johannes, Freund, Adam, Wright, Kevin M, Churchill, Gary A
Publicado 2021

FGF21 mimetic antibody stimulates UCP1-independent brown fat thermogenesis via FGFR1/βKlotho complex in non-adipocytes

por Chen, Mark Z., Chang, Joshua C., Zavala-Solorio, Jose, Kates, Lance, Thai, Minh, Ogasawara, Annie, Bai, Xiaobo, Flanagan, Sean, Nunez, Victor, Phamluong, Khanhky, Ziai, James, Newman, Robert, Warming, Søren, Kolumam, Ganesh, Sonoda, Junichiro
Publicado 2017

MANF regulates metabolic and immune homeostasis in ageing and protects against liver damage

por Sousa-Victor, Pedro, Neves, Joana, Cedron-Craft, Wendy, Ventura, P. Britten, Liao, Chen-Yu, Riley, Rebeccah R., Soifer, Ilya, van Bruggen, Nicholas, Kolumam, Ganesh A., Villeda, Saul A., Lamba, Deepak A., Jasper, Heinrich
Publicado 2019

CD38 inhibitor 78c increases mice lifespan and healthspan in a model of chronological aging

por Peclat, Thais R., Thompson, Katie L., Warner, Gina M., Chini, Claudia C.S., Tarragó, Mariana G., Mazdeh, Delaram Z., Zhang, Chunlian, Zavala‐Solorio, Jose, Kolumam, Ganesh, Liang Wong, Yao, Cohen, Robert L., Chini, Eduardo N.
Publicado 2022

Inhibition of longevity regulator PAPP‐A modulates tissue homeostasis via restraint of mesenchymal stromal cells

por Mohrin, Mary, Liu, Justin, Zavala‐Solorio, Jose, Bhargava, Sakshi, Maxwell Trumble, John, Brito, Alyssa, Hu, Dorothy, Brooks, Daniel, Koukos, Georgios, Alabdulaaly, Lama, Paw, Jonathan S., Hake, Kayley, Kolumam, Ganesh, Bouxsein, Mary L., Baron, Roland, Kutskova, Yuliya, Freund, Adam
Publicado 2021

An immune-based tool platform for in vivo cell clearance

por Zhang, Jieqiong, Tsukui, Tatsuya, Wu, Xiumin, Brito, Alyssa, Trumble, John Maxwell, Caraballo, Juan C, Allen, Greg M, Zavala-Solorio, José, Zhang, Chunlian, Paw, Jonathan, Lim, Wendell A, Geng, Jiefei, Kutskova, Yuliya, Freund, Adam, Kolumam, Ganesh, Sheppard, Dean, Cohen, Robert L
Publicado 2023

Cross-species gene expression analysis identifies a novel set of genes implicated in human insulin sensitivity

por Chaudhuri, Rima, Khoo, Poh Sim, Tonks, Katherine, Junutula, Jagath R, Kolumam, Ganesh, Modrusan, Zora, Samocha-Bonet, Dorit, Meoli, Christopher C, Hocking, Samantha, Fazakerley, Daniel J, Stöckli, Jacqueline, Hoehn, Kyle L, Greenfield, Jerry R, Yang, Jean Yee Hwa, James, David E
Publicado 2015

3D mouse pose from single-view video and a new dataset

por Hu, Bo, Seybold, Bryan, Yang, Shan, Sud, Avneesh, Liu, Yi, Barron, Karla, Cha, Paulyn, Cosino, Marcelo, Karlsson, Ellie, Kite, Janessa, Kolumam, Ganesh, Preciado, Joseph, Zavala-Solorio, José, Zhang, Chunlian, Zhang, Xiaomeng, Voorbach, Martin, Tovcimak, Ann E., Ruby, J. Graham, Ross, David A.
Publicado 2023

Mitochondrial CoQ deficiency is a common driver of mitochondrial oxidants and insulin resistance

por Fazakerley, Daniel J, Chaudhuri, Rima, Yang, Pengyi, Maghzal, Ghassan J, Thomas, Kristen C, Krycer, James R, Humphrey, Sean J, Parker, Benjamin L, Fisher-Wellman, Kelsey H, Meoli, Christopher C, Hoffman, Nolan J, Diskin, Ciana, Burchfield, James G, Cowley, Mark J, Kaplan, Warren, Modrusan, Zora, Kolumam, Ganesh, Yang, Jean YH, Chen, Daniel L, Samocha-Bonet, Dorit, Greenfield, Jerry R, Hoehn, Kyle L, Stocker, Roland, James, David E
Publicado 2018

Sustained Brown Fat Stimulation and Insulin Sensitization by a Humanized Bispecific Antibody Agonist for Fibroblast Growth Factor Receptor 1/βKlotho Complex

por Kolumam, Ganesh, Chen, Mark Z., Tong, Raymond, Zavala-Solorio, Jose, Kates, Lance, van Bruggen, Nicholas, Ross, Jed, Wyatt, Shelby K., Gandham, Vineela D., Carano, Richard A.D., Dunshee, Diana Ronai, Wu, Ai-Luen, Haley, Benjamin, Anderson, Keith, Warming, Søren, Rairdan, Xin Y., Lewin-Koh, Nicholas, Zhang, Yingnan, Gutierrez, Johnny, Baruch, Amos, Gelzleichter, Thomas R., Stevens, Dale, Rajan, Sharmila, Bainbridge, Travis W., Vernes, Jean-Michel, Meng, Y. Gloria, Ziai, James, Soriano, Robert H., Brauer, Matthew J., Chen, Yongmei, Stawicki, Scott, Kim, Hok Seon, Comps-Agrar, Laëtitia, Luis, Elizabeth, Spiess, Christoph, Wu, Yan, Ernst, James A., McGuinness, Owen P., Peterson, Andrew S., Sonoda, Junichiro
Publicado 2015