In the business of base editors: Evolution from bench to bedside

por Porto, Elizabeth M., Komor, Alexis C.
Publicado 2023

An Unusual Ligand Coordination Gives Rise to a New Family of Rhodium Metalloinsertors with Improved Selectivity and Potency

por Komor, Alexis C., Barton, Jacqueline K.
Publicado 2014

The use of base editing technology to characterize single nucleotide variants

por McDaniel, Sophia, Komor, Alexis, Goren, Alon
Publicado 2022

Rewriting Human History and Empowering Indigenous Communities with Genome Editing Tools

por Fox, Keolu, Rallapalli, Kartik Lakshmi, Komor, Alexis C.
Publicado 2020

Computer simulations explain mutation-induced effects on the DNA editing by adenine base editors

por Rallapalli, Kartik L., Komor, Alexis C., Paesani, Francesco
Publicado 2020

Targeting double-strand break indel byproducts with secondary guide RNAs improves Cas9 HDR-mediated genome editing efficiencies

por Bodai, Zsolt, Bishop, Alena L., Gantz, Valentino M., Komor, Alexis C.
Publicado 2022

Programmable editing of a target base in genomic DNA without double-stranded DNA cleavage

por Komor, Alexis C., Kim, Yongjoo B., Packer, Michael S., Zuris, John A., Liu, David R.
Publicado 2016

Curing “GFP-itis” in Bacteria with Base Editors: Development of a Genome Editing Science Program Implemented with High School Biology Students

por Vasquez, Carlos A., Evanoff, Mallory, Ranzau, Brodie L., Gu, Sifeng, Deters, Emma, Komor, Alexis C.
Publicado 2023

Increasing the genome-targeting scope and precision of base editing with engineered Cas9-cytidine deaminase fusions

por Kim, Y. Bill, Komor, Alexis C., Levy, Jonathan M., Packer, Michael S., Zhao, Kevin T., Liu, David R.
Publicado 2017

An Inducible, Isogenic Cancer Cell Line System for Targeting the State of Mismatch Repair Deficiency

por Bailis, Julie M., Gordon, Marcia L., Gurgel, Jesse L., Komor, Alexis C., Barton, Jacqueline K., Kirsch, Ilan R.
Publicado 2013

Double-tap gene drive uses iterative genome targeting to help overcome resistance alleles

por Bishop, Alena L., López Del Amo, Víctor, Okamoto, Emily M., Bodai, Zsolt, Komor, Alexis C., Gantz, Valentino M.
Publicado 2022

Examination of the Cell Cycle Dependence of Cytosine and Adenine Base Editors

por Burnett, Cameron A., Wong, Ashley T., Vasquez, Carlos A., McHugh, Colleen A., Yeo, Gene W., Komor, Alexis C.
Publicado 2022

Improving the DNA specificity and applicability of base editing through protein engineering and protein delivery

por Rees, Holly A., Komor, Alexis C., Yeh, Wei-Hsi, Caetano-Lopes, Joana, Warman, Matthew, Edge, Albert S. B., Liu, David R.
Publicado 2017

Programmable base editing of A•T to G•C in genomic DNA without DNA cleavage

por Gaudelli, Nicole M., Komor, Alexis C., Rees, Holly A., Packer, Michael S., Badran, Ahmed H., Bryson, David I., Liu, David R.
Publicado 2017

Improved base excision repair inhibition and bacteriophage Mu Gam protein yields C:G-to-T:A base editors with higher efficiency and product purity

por Komor, Alexis C., Zhao, Kevin T., Packer, Michael S., Gaudelli, Nicole M., Waterbury, Amanda L., Koblan, Luke W., Kim, Y. Bill, Badran, Ahmed H., Liu, David R.
Publicado 2017

Expanded palette of RNA base editors for comprehensive RBP-RNA interactome studies

por Medina-Munoz, Hugo C., Kofman, Eric, Jagannatha, Pratibha, Boyle, Evan A., Yu, Tao, Jones, Krysten L., Mueller, Jasmine R., Lykins, Grace D., Doudna, Andrew T., Park, Samuel S., Blue, Steven M., Ranzau, Brodie L., Kohli, Rahul M., Komor, Alexis C., Yeo, Gene W.
Publicado 2023