The bHLH transcription factor Mist1 is required to maintain exocrine pancreas cell organization and acinar cell identity

por Pin, Christopher L., Rukstalis, J. Michael, Johnson, Charis, Konieczny, Stephen F.
Publicado 2001

Maintenance of Acinar Cell Organization is Critical to Preventing Kras-Induced Acinar-Ductal Metaplasia

por Shi, Guanglu, DiRenzo, Daniel, Qu, Chunjing, Barney, Darci, Miley, David, Konieczny, Stephen F.
Publicado 2012

Silencing Mist1 Gene Expression Is Essential for Recovery from Acute Pancreatitis

por Karki, Anju, Humphrey, Sean E., Steele, Rebecca E., Hess, David A., Taparowsky, Elizabeth J., Konieczny, Stephen F.
Publicado 2015

Subtype-specific characterization of breast cancer invasion using a microfluidic tumor platform

por Moon, Hye-ran, Ospina-Muñoz, Natalia, Noe-Kim, Victoria, Yang, Yi, Elzey, Bennett D., Konieczny, Stephen F., Han, Bumsoo
Publicado 2020

The Xbp1-regulated transcription factor Mist1 restricts antibody secretion by restraining Blimp1 expression in plasma cells

por Wöhner, Miriam, Pinter, Theresa, Bönelt, Peter, Hagelkruys, Astrid, Kostanova-Poliakova, Daniela, Stadlmann, Johannes, Konieczny, Stephen F., Fischer, Maria, Jaritz, Markus, Busslinger, Meinrad
Publicado 2022

Induced PTF1a expression in pancreatic ductal adenocarcinoma cells activates acinar gene networks, reduces tumorigenic properties, and sensitizes cells to gemcitabine treatment

por Jakubison, Brad L., Schweickert, Patrick G., Moser, Sarah E., Yang, Yi, Gao, Hongyu, Scully, Kathleen, Itkin‐Ansari, Pamela, Liu, Yunlong, Konieczny, Stephen F.
Publicado 2018

The Basic Helix-Loop-Helix Transcription Factor E47 Reprograms Human Pancreatic Cancer Cells to a Quiescent Acinar State With Reduced Tumorigenic Potential

por Kim, SangWun, Lahmy, Reyhaneh, Riha, Chelsea, Yang, Challeng, Jakubison, Brad L., van Niekerk, Jaco, Staub, Claudio, Wu, Yifan, Gates, Keith, Dong, Duc Si, Konieczny, Stephen F., Itkin-Ansari, Pamela
Publicado 2015

Notch activation drives adipocyte dedifferentiation and tumorigenic transformation in mice

por Bi, Pengpeng, Yue, Feng, Karki, Anju, Castro, Beatriz, Wirbisky, Sara E., Wang, Chao, Durkes, Abigail, Elzey, Bennett D., Andrisani, Ourania M., Bidwell, Christopher A., Freeman, Jennifer L., Konieczny, Stephen F., Kuang, Shihuan
Publicado 2016

A single transcription factor is sufficient to induce and maintain secretory cell architecture

por Lo, Hei-Yong G., Jin, Ramon U., Sibbel, Greg, Liu, Dengqun, Karki, Anju, Joens, Matthew S., Madison, Blair B., Zhang, Bo, Blanc, Valerie, Fitzpatrick, James A.J., Davidson, Nicholas O., Konieczny, Stephen F., Mills, Jason C.
Publicado 2017

CXCR4-expressing Mist1(+) progenitors in the gastric antrum contribute to gastric cancer development

por Sakitani, Kosuke, Hayakawa, Yoku, Deng, Huan, Ariyama, Hiroshi, Kinoshita, Hiroto, Konishi, Mitsuru, Ono, Satoshi, Suzuki, Nobumi, Ihara, Sozaburo, Niu, Zhengchuan, Kim, Woosook, Tanaka, Takayuki, Liu, Haibo, Chen, Xiaowei, Tailor, Yagnesh, Fox, James G., Konieczny, Stephen F., Onodera, Hiroshi, Sepulveda, Antonia R., Asfaha, Samuel, Hirata, Yoshihiro, Worthley, Daniel L., Koike, Kazuhiko, Wang, Timothy C.
Publicado 2017

Stromal ETS2 Regulates Chemokine Production and Immune Cell Recruitment during Acinar-to-Ductal Metaplasia()

por Pitarresi, Jason R., Liu, Xin, Sharma, Sudarshana M., Cuitiño, Maria C., Kladney, Raleigh D., Mace, Thomas A., Donohue, Sydney, Nayak, Sunayana G., Qu, Chunjing, Lee, James, Woelke, Sarah A., Trela, Stefan, LaPak, Kyle, Yu, Lianbo, McElroy, Joseph, Rosol, Thomas J., Shakya, Reena, Ludwig, Thomas, Lesinski, Gregory B., Fernandez, Soledad A., Konieczny, Stephen F., Leone, Gustavo, Wu, Jinghai, Ostrowski, Michael C.
Publicado 2016

Genetic ablation of Smoothened in pancreatic fibroblasts increases acinar–ductal metaplasia

por Liu, Xin, Pitarresi, Jason R., Cuitiño, Maria C., Kladney, Raleigh D., Woelke, Sarah A., Sizemore, Gina M., Nayak, Sunayana G., Egriboz, Onur, Schweickert, Patrick G., Yu, Lianbo, Trela, Stefan, Schilling, Daniel J., Halloran, Shannon K., Li, Maokun, Dutta, Shourik, Fernandez, Soledad A., Rosol, Thomas J., Lesinski, Gregory B., Shakya, Reena, Ludwig, Thomas, Konieczny, Stephen F., Leone, Gustavo, Wu, Jinghai, Ostrowski, Michael C.
Publicado 2016

Disruption of stromal hedgehog signaling initiates RNF5-mediated proteasomal degradation of PTEN and accelerates pancreatic tumor growth

por Pitarresi, Jason R, Liu, Xin, Avendano, Alex, Thies, Katie A, Sizemore, Gina M, Hammer, Anisha M, Hildreth, Blake E, Wang, David J, Steck, Sarah A, Donohue, Sydney, Cuitiño, Maria C, Kladney, Raleigh D, Mace, Thomas A, Chang, Jonathan J, Ennis, Christina S, Li, Huiqing, Reeves, Roger H, Blackshaw, Seth, Zhang, Jianying, Yu, Lianbo, Fernandez, Soledad A, Frankel, Wendy L, Bloomston, Mark, Rosol, Thomas J, Lesinski, Gregory B, Konieczny, Stephen F, Guttridge, Denis C, Rustgi, Anil K, Leone, Gustavo, Song, Jonathan W, Wu, Jinghai, Ostrowski, Michael C
Publicado 2018