Deferiprone and Iron–Maltol: Forty Years since Their Discovery and Insights into Their Drug Design, Development, Clinical Use and Future Prospects

por Kontoghiorghes, George J.
Publicado 2023

The Vital Role Played by Deferiprone in the Transition of Thalassaemia from a Fatal to a Chronic Disease and Challenges in Its Repurposing for Use in Non-Iron-Loaded Diseases

por Kontoghiorghes, George J.
Publicado 2023

Iron Load Toxicity in Medicine: From Molecular and Cellular Aspects to Clinical Implications

por Kontoghiorghes, George J.
Publicado 2023

Advances on Chelation and Chelator Metal Complexes in Medicine †

por Kontoghiorghes, George J.
Publicado 2020

Differences between the European Union and United States of America in Drug Regulatory Affairs Affect Global Patient Safety Standards and Public Health Awareness: The Case of Defer...

por Kontoghiorghes, George J.
Publicado 2021

Ethics in Medicines: Exposing Unethical Practices and Corruption in All Sectors of Medicines Is Essential for Improving Global Public Health and Saving Patients’ Lives

por Kontoghiorghes, George J.
Publicado 2021

Questioning Established Theories and Treatment Methods Related to Iron and Other Metal Metabolic Changes, Affecting All Major Diseases and Billions of Patients

por Kontoghiorghes, George J.
Publicado 2022

Deferiprone: A Forty-Year-Old Multi-Targeting Drug with Possible Activity against COVID-19 and Diseases of Similar Symptomatology

por Kontoghiorghes, George J.
Publicado 2022

New Iron Metabolic Pathways and Chelation Targeting Strategies Affecting the Treatment of All Types and Stages of Cancer

por Kontoghiorghes, George J.
Publicado 2022

Efficacy and safety of iron-chelation therapy with deferoxamine, deferiprone, and deferasirox for the treatment of iron-loaded patients with non-transfusion-dependent thalassemia s...

por Kontoghiorghe, Christina N, Kontoghiorghes, George J
Publicado 2016

Iron and Chelation in Biochemistry and Medicine: New Approaches to Controlling Iron Metabolism and Treating Related Diseases

por Kontoghiorghes, George J., Kontoghiorghe, Christina N.
Publicado 2020

Transfusion-Related Acute Lung Injury (TRALI) in two Thalassaemia Patients Caused by the Same Multiparous Blood Donor

por Kolnagou, Annita, Kontoghiorghe, Christina N, Kontoghiorghes, George J
Publicado 2017

Phytochelators Intended for Clinical Use in Iron Overload, Other Diseases of Iron Imbalance and Free Radical Pathology

por Kontoghiorghe, Christina N., Kolnagou, Annita, Kontoghiorghes, George J.
Publicado 2015

The History of Deferiprone (L1) and the Paradigm of the Complete Treatment of Iron Overload in Thalassaemia

por Kontoghiorghes, George J., Kleanthous, Marios, Kontoghiorghe, Christina N.
Publicado 2020

Conventional and Unconventional Approaches for Innovative Drug Treatments in COVID-19: Looking Outside of Plato’s Cave

por Kontoghiorghes, George J., Kolnagou, Annita, Fetta, Stella, Kontoghiorghe, Christina N.
Publicado 2021

Metal Complexes of Omadine (N-Hydroxypyridine-2-thione): Differences of Antioxidant and Pro-Oxidant Behavior in Light and Dark Conditions with Possible Toxicity Implications

por Selyutina, Olga Yu., Timoshnikov, Viktor A., Polyakov, Nikolay E., Kontoghiorghes, George J.
Publicado 2023

Redox Interactions of Vitamin C and Iron: Inhibition of the Pro-Oxidant Activity by Deferiprone

por Timoshnikov, Viktor A., Kobzeva, Tatyana V., Polyakov, Nikolay E., Kontoghiorghes, George J.
Publicado 2020

New Era in the Treatment of Iron Deficiency Anaemia Using Trimaltol Iron and Other Lipophilic Iron Chelator Complexes: Historical Perspectives of Discovery and Future Applications

por Kontoghiorghes, George J., Kolnagou, Annita, Demetriou, Theodora, Neocleous, Marina, Kontoghiorghe, Christina N.
Publicado 2021

Mechanistic Insights of Chelator Complexes with Essential Transition Metals: Antioxidant/Pro-Oxidant Activity and Applications in Medicine

por Timoshnikov, Viktor A., Selyutina, Olga Yu., Polyakov, Nikolay E., Didichenko, Victoria, Kontoghiorghes, George J.
Publicado 2022

Increased Free Radical Generation during the Interaction of a Quinone-Quinoline Chelator with Metal Ions and the Enhancing Effect of Light

por Selyutina, Olga Yu., Babenko, Simon V., Slepneva, Irina A., Polyakov, Nikolay E., Kontoghiorghes, George J.
Publicado 2023