Discovery of Tenapanor: A First-in-Class Minimally Systemic Inhibitor of Intestinal Na(+)/H(+) Exchanger Isoform 3

por Jacobs, Jeffrey W., Leadbetter, Michael R., Bell, Noah, Koo-McCoy, Samantha, Carreras, Christopher W., He, Limin, Kohler, Jill, Kozuka, Kenji, Labonté, Eric D., Navre, Marc, Spencer, Andrew G., Charmot, Dominique
Publicado 2022

Development and Characterization of a Human and Mouse Intestinal Epithelial Cell Monolayer Platform

por Kozuka, Kenji, He, Ying, Koo-McCoy, Samantha, Kumaraswamy, Padmapriya, Nie, Baoming, Shaw, Karen, Chan, Priscilla, Leadbetter, Michael, He, Limin, Lewis, Jason G., Zhong, Ziyang, Charmot, Dominique, Balaa, Marwan, King, Andrew J., Caldwell, Jeremy S., Siegel, Matthew
Publicado 2017

Intestinal TGR5 agonism improves hepatic steatosis and insulin sensitivity in Western diet-fed mice

por Finn, Patricia D., Rodriguez, David, Kohler, Jill, Jiang, Zhengfeng, Wan, Sindy, Blanco, Erick, King, Andrew J., Chen, Tao, Bell, Noah, Dragoli, Dean, Jacobs, Jeffrey W., Jain, Rakesh, Leadbetter, Michael, Siegel, Matthew, Carreras, Christopher W., Koo-McCoy, Samantha, Shaw, Karen, Le, Cathy, Vanegas, Sandra, Hsu, I-Hsin, Kozuka, Kenji, Okamoto, Keiko, Caldwell, Jeremy S., Lewis, Jason G.
Publicado 2019