High-Resolution Transcriptomic and Proteomic Profiling of Heterogeneity of Brain-Derived Microglia in Multiple Sclerosis

por Miedema, Anneke, Wijering, Marion H. C., Eggen, Bart J. L., Kooistra, Susanne M.
Publicado 2020

Jmjd2/Kdm4 demethylases are required for expression of Il3ra and survival of acute myeloid leukemia cells

por Agger, Karl, Miyagi, Satoru, Pedersen, Marianne Terndrup, Kooistra, Susanne M., Johansen, Jens Vilstrup, Helin, Kristian
Publicado 2016

Exploring the VISTA of microglia: immune checkpoints in CNS inflammation

por Borggrewe, Malte, Kooistra, Susanne M., Noelle, Randolph J., Eggen, Bart J. L., Laman, Jon D.
Publicado 2020

Pathological ultrastructural alterations of myelinated axons in normal appearing white matter in progressive multiple sclerosis

por Oost, Wendy, Huitema, Allard J., Kats, Kim, Giepmans, Ben N. G., Kooistra, Susanne M., Eggen, Bart J. L., Baron, Wia
Publicado 2023

The Histone Demethylase Jarid1b Ensures Faithful Mouse Development by Protecting Developmental Genes from Aberrant H3K4me3

por Albert, Mareike, Schmitz, Sandra U., Kooistra, Susanne M., Malatesta, Martina, Morales Torres, Cristina, Rekling, Jens C., Johansen, Jens V., Abarrategui, Iratxe, Helin, Kristian
Publicado 2013

Regionally diverse astrocyte subtypes and their heterogeneous response to EAE

por Borggrewe, Malte, Grit, Corien, Vainchtein, Ilia D., Brouwer, Nieske, Wesseling, Evelyn M., Laman, Jon D., Eggen, Bart J. L., Kooistra, Susanne M., Boddeke, Erik W. G. M.
Publicado 2020

Epigenetic regulation of innate immune memory in microglia

por Zhang, Xiaoming, Kracht, Laura, Lerario, Antonio M., Dubbelaar, Marissa L., Brouwer, Nieske, Wesseling, Evelyn M., Boddeke, Erik W. G. M., Eggen, Bart J. L., Kooistra, Susanne M.
Publicado 2022

UTF1 is a chromatin-associated protein involved in ES cell differentiation

por van den Boom, Vincent, Kooistra, Susanne M., Boesjes, Marije, Geverts, Bart, Houtsmuller, Adriaan B., Monzen, Koshiro, Komuro, Issei, Essers, Jeroen, Drenth-Diephuis, Loes J., Eggen, Bart J.L.
Publicado 2007

Jarid2 binds mono-ubiquitylated H2A lysine 119 to mediate crosstalk between Polycomb complexes PRC1 and PRC2

por Cooper, Sarah, Grijzenhout, Anne, Underwood, Elizabeth, Ancelin, Katia, Zhang, Tianyi, Nesterova, Tatyana B., Anil-Kirmizitas, Burcu, Bassett, Andrew, Kooistra, Susanne M., Agger, Karl, Helin, Kristian, Heard, Edith, Brockdorff, Neil
Publicado 2016

Kinetic analysis of Cas12a and Cas13a RNA-Guided nucleases for development of improved CRISPR-Based diagnostics

por Nalefski, Eric A., Patel, Nidhi, Leung, Philip J.Y., Islam, Zeba, Kooistra, Remy M., Parikh, Ishira, Marion, Estelle, Knott, Gavin J., Doudna, Jennifer A., Le Ny, Anne-Laure M., Madan, Damian
Publicado 2021

VISTA regulates microglia homeostasis and myelin phagocytosis, and is associated with MS lesion pathology

por Borggrewe, Malte, Kooistra, Susanne M., Wesseling, Evelyn M., Gierschek, Fenja L., Brummer, Maaike L., Nowak, Elizabeth C., Medeiros-Furquim, Tiago, Otto, Tegan A., Lee, Sam W., Noelle, Randolph J., Eggen, Bart J. L., Laman, Jon D.
Publicado 2021

Early-life stress lastingly impacts microglial transcriptome and function under basal and immune-challenged conditions

por Reemst, Kitty, Kracht, Laura, Kotah, Janssen M., Rahimian, Reza, van Irsen, Astrid A. S., Congrains Sotomayor, Gonzalo, Verboon, Laura N., Brouwer, Nieske, Simard, Sophie, Turecki, Gustavo, Mechawar, Naguib, Kooistra, Susanne M., Eggen, Bart J. L., Korosi, Aniko
Publicado 2022

Intrinsic DNA damage repair deficiency results in progressive microglia loss and replacement

por Zhang, Xiaoming, Heng, Yang, Kooistra, Susanne M., van Weering, Hilmar R. J., Brummer, Maaike L., Gerrits, Emma, Wesseling, Evelyn M., Brouwer, Nieske, Nijboer, Tjalling W., Dubbelaar, Marissa L., Boddeke, Erik W. G. M., Eggen, Bart J. L.
Publicado 2020

Transcriptional profiling of macaque microglia reveals an evolutionary preserved gene expression program

por Dubbelaar, M.L., Misrielal, C., Bajramovic, J.J., Burm, S.M., Zuiderwijk-Sick, E.A., Brouwer, N., Grit, C., Kooistra, S.M., Shinjo, S.M.O., Marie, S.K.N., Boddeke, H.W.G.M., Eggen, B.J.L.
Publicado 2021

Brain macrophages acquire distinct transcriptomes in multiple sclerosis lesions and normal appearing white matter

por Miedema, Anneke, Gerrits, Emma, Brouwer, Nieske, Jiang, Qiong, Kracht, Laura, Meijer, Michel, Nutma, Erik, Peferoen-Baert, Regina, Pijnacker, Anna T. E., Wesseling, Evelyn M., Wijering, Marion H. C., Gabius, Hans-Joachim, Amor, Sandra, Eggen, Bart J. L., Kooistra, Susanne M.
Publicado 2022

Characterizing microglial gene expression in a model of secondary progressive multiple sclerosis

por Vainchtein, Ilia D., Alsema, Astrid M., Dubbelaar, Marissa L., Grit, Corien, Vinet, Jonathan, van Weering, Hilmar R. J., Al‐Izki, Sarah, Biagini, Giuseppe, Brouwer, Nieske, Amor, Sandra, Baker, David, Eggen, Bart J. L., Boddeke, Erik W. G. M., Kooistra, Susanne M.
Publicado 2022

Distinct amyloid-β and tau-associated microglia profiles in Alzheimer’s disease

por Gerrits, Emma, Brouwer, Nieske, Kooistra, Susanne M., Woodbury, Maya E., Vermeiren, Yannick, Lambourne, Mirjam, Mulder, Jan, Kummer, Markus, Möller, Thomas, Biber, Knut, Dunnen, Wilfred F. A. den, De Deyn, Peter P., Eggen, Bart J. L., Boddeke, Erik W. G. M.
Publicado 2021

Low-Fat Diet With Caloric Restriction Reduces White Matter Microglia Activation During Aging

por Yin, Zhuoran, Raj, Divya D., Schaafsma, Wandert, van der Heijden, Roel A., Kooistra, Susanne M., Reijne, Aaffien C., Zhang, Xiaoming, Moser, Jill, Brouwer, Nieske, Heeringa, Peter, Yi, Chun-Xia, van Dijk, Gertjan, Laman, Jon D., Boddeke, Erik W. G. M., Eggen, Bart J. L.
Publicado 2018

Profiling Microglia From Alzheimer’s Disease Donors and Non-demented Elderly in Acute Human Postmortem Cortical Tissue

por Alsema, Astrid M., Jiang, Qiong, Kracht, Laura, Gerrits, Emma, Dubbelaar, Marissa L., Miedema, Anneke, Brouwer, Nieske, Hol, Elly M., Middeldorp, Jinte, van Dijk, Roland, Woodbury, Maya, Wachter, Astrid, Xi, Simon, Möller, Thomas, Biber, Knut P., Kooistra, Susanne M., Boddeke, Erik W. G. M., Eggen, Bart J. L.
Publicado 2020