Modelling mosquito infection at natural parasite densities identifies drugs targeting EF2, PI4K or ATP4 as key candidates for interrupting malaria transmission

por Dechering, Koen J., Duerr, Hans-Peter, Koolen, Karin M. J., Gemert, Geert-Jan van, Bousema, Teun, Burrows, Jeremy, Leroy, Didier, Sauerwein, Robert W.
Publicado 2017

Barcoded Asaia bacteria enable mosquito in vivo screens and identify novel systemic insecticides and inhibitors of malaria transmission

por Sturm, Angelika, Vos, Martijn W., Henderson, Rob, Eldering, Maarten, Koolen, Karin M. J., Sheshachalam, Avinash, Favia, Guido, Samby, Kirandeep, Herreros, Esperanza, Dechering, Koen J.
Publicado 2021

A semi-automated luminescence based standard membrane feeding assay identifies novel small molecules that inhibit transmission of malaria parasites by mosquitoes

por Vos, Martijn W., Stone, Will J. R., Koolen, Karin M., van Gemert, Geert-Jan, van Schaijk, Ben, Leroy, Didier, Sauerwein, Robert W., Bousema, Teun, Dechering, Koen J.
Publicado 2015

An inter-laboratory comparison of standard membrane-feeding assays for evaluation of malaria transmission-blocking vaccines

por Miura, Kazutoyo, Stone, Will J. R., Koolen, Karin M., Deng, Bingbing, Zhou, Luwen, van Gemert, Geert-Jan, Locke, Emily, Morin, Merribeth, Bousema, Teun, Sauerwein, Robert W., Long, Carole A., Dechering, Koen J.
Publicado 2016

A P. falciparum NF54 Reporter Line Expressing mCherry-Luciferase in Gametocytes, Sporozoites, and Liver-Stages

por Marin-Mogollon, Catherin, Salman, Ahmed M., Koolen, Karin M. J., Bolscher, Judith M., van Pul, Fiona J. A., Miyazaki, Shinya, Imai, Takashi, Othman, Ahmad Syibli, Ramesar, Jai, van Gemert, Geert-Jan, Kroeze, Hans, Chevalley-Maurel, Severine, Franke-Fayard, Blandine, Sauerwein, Robert W., Hill, Adrian V. S., Dechering, Koen J., Janse, Chris J., Khan, Shahid M.
Publicado 2019

Preclinical characterization and target validation of the antimalarial pantothenamide MMV693183

por de Vries, Laura E., Jansen, Patrick A. M., Barcelo, Catalina, Munro, Justin, Verhoef, Julie M. J., Pasaje, Charisse Flerida A., Rubiano, Kelly, Striepen, Josefine, Abla, Nada, Berning, Luuk, Bolscher, Judith M., Demarta-Gatsi, Claudia, Henderson, Rob W. M., Huijs, Tonnie, Koolen, Karin M. J., Tumwebaze, Patrick K., Yeo, Tomas, Aguiar, Anna C. C., Angulo-Barturen, Iñigo, Churchyard, Alisje, Baum, Jake, Fernández, Benigno Crespo, Fuchs, Aline, Gamo, Francisco-Javier, Guido, Rafael V. C., Jiménez-Diaz, María Belén, Pereira, Dhelio B., Rochford, Rosemary, Roesch, Camille, Sanz, Laura M., Trevitt, Graham, Witkowski, Benoit, Wittlin, Sergio, Cooper, Roland A., Rosenthal, Philip J., Sauerwein, Robert W., Schalkwijk, Joost, Hermkens, Pedro H. H., Bonnert, Roger V., Campo, Brice, Fidock, David A., Llinás, Manuel, Niles, Jacquin C., Kooij, Taco W. A., Dechering, Koen J.
Publicado 2022