Drug Repurposing, a Fast-Track Approach to Develop Effective Treatments for Glioblastoma

por Ntafoulis, Ioannis, Koolen, Stijn L. W., Leenstra, Sieger, Lamfers, Martine L. M.
Publicado 2022

Recent Clinical Developments of Nanomediated Drug Delivery Systems of Taxanes for the Treatment of Cancer

por van Eerden, Ruben A G, Mathijssen, Ron H J, Koolen, Stijn L W
Publicado 2020

Feasibility of Extrapolating Randomly Taken Plasma Samples to Trough Levels for Therapeutic Drug Monitoring Purposes of Small Molecule Kinase Inhibitors

por van Eerden, Ruben A. G., Oomen-de Hoop, Esther, Noordam, Aad, Mathijssen, Ron H. J., Koolen, Stijn L. W.
Publicado 2021

Inhibiting CDK4/6 in Breast Cancer with Palbociclib, Ribociclib, and Abemaciclib: Similarities and Differences

por Braal, C. Louwrens, Jongbloed, Elisabeth M., Wilting, Saskia M., Mathijssen, Ron H. J., Koolen, Stijn L. W., Jager, Agnes
Publicado 2020

Tamoxifen use and potential effects on liver parenchyma: A long‐term prospective transient elastographic evaluation

por Braal, C. Louwrens, de Knegt, Robert J., Jager, Agnes, Koolen, Stijn L. W., Mathijssen, Ron H. J., Eechoute, Karel
Publicado 2022

Integrated Data Analysis of Six Clinical Studies Points Toward Model-Informed Precision Dosing of Tamoxifen

por Klopp-Schulze, Lena, Mueller-Schoell, Anna, Neven, Patrick, Koolen, Stijn L. W., Mathijssen, Ron H. J., Joerger, Markus, Kloft, Charlotte
Publicado 2020

Blood-based extracellular matrix biomarkers are correlated with clinical outcome after PD-1 inhibition in patients with metastatic melanoma

por Hurkmans, Daan P, Jensen, Christina, Koolen, Stijn L W, Aerts, Joachim, Karsdal, Morten Asser, Mathijssen, Ron H J, Willumsen, Nicholas
Publicado 2020

Therapeutic Drug Monitoring-Guided Adjuvant Tamoxifen Dosing in Patients with Early Breast Cancer: A Cost-Effectiveness Analysis from the Prospective TOTAM Trial

por Braal, C. Louwrens, Kleijburg, Anne, Jager, Agnes, Koolen, Stijn L. W., Mathijssen, Ron H. J., Corro Ramos, Isaac, Wetzelaer, Pim, Uyl-de Groot, Carin A.
Publicado 2022

Therapeutic Drug Monitoring of Kinase Inhibitors in Oncology

por van der Kleij, Maud B. A., Guchelaar, Niels A. D., Mathijssen, Ron H. J., Versluis, Jurjen, Huitema, Alwin D. R., Koolen, Stijn L. W., Steeghs, Neeltje
Publicado 2023

A limited sampling schedule to estimate individual pharmacokinetics of pemetrexed in patients with varying renal functions

por de Rouw, Nikki, Visser, Sabine, Koolen, Stijn L. W., Aerts, Joachim G. J. V., van den Heuvel, Michel M., Derijks, Hieronymus J., Burger, David M., ter Heine, Rob
Publicado 2019

Development of [(225)Ac]Ac-PSMA-I&T for Targeted Alpha Therapy According to GMP Guidelines for Treatment of mCRPC

por Hooijman, Eline L., Chalashkan, Yozlem, Ling, Sui Wai, Kahyargil, Figen F., Segbers, Marcel, Bruchertseifer, Frank, Morgenstern, Alfred, Seimbille, Yann, Koolen, Stijn L. W., Brabander, Tessa, de Blois, Erik
Publicado 2021

Factors affecting inter-individual variability in endoxifen concentrations in patients with breast cancer: results from the prospective TOTAM trial

por Braal, C. Louwrens, Westenberg, Justin D., Buijs, Sanne M., Abrams, Steven, Mulder, Tessa A. M., van Schaik, Ron H. N., Koolen, Stijn L. W., Jager, Agnes, Mathijssen, Ron H. J.
Publicado 2022

Combining Sorafenib and Immunosuppression in Liver Transplant Recipients with Hepatocellular Carcinoma

por Hussaarts, Koen G. A. M., van Doorn, Leni, Bins, Sander, Sprengers, Dave, de Bruijn, Peter, van Leeuwen, Roelof W. F., Koolen, Stijn L. W., van Gelder, Teun, Mathijssen, Ron H. J.
Publicado 2021

The Influence of Body Composition on the Systemic Exposure of Paclitaxel in Esophageal Cancer Patients

por van Doorn, Leni, Crombag, Marie-Rose B. S., Rier, Hánah N., van Vugt, Jeroen L. A., van Kesteren, Charlotte, Bins, Sander, Mathijssen, Ron H. J., Levin, Mark-David, Koolen, Stijn L. W.
Publicado 2021

Population Pharmacokinetics of Oxycodone and Metabolites in Patients with Cancer-Related Pain

por Agema, Bram C., Oosten, Astrid W., Sassen, Sebastiaan D.T., Rietdijk, Wim J.R., van der Rijt, Carin C.D., Koch, Birgit C.P., Mathijssen, Ron H.J., Koolen, Stijn L.W.
Publicado 2021

Effects of smoking and body mass index on the exposure of fentanyl in patients with cancer

por Kuip, Evelien J. M., Oldenmenger, Wendy H., Thijs—Visser, Martine F., de Bruijn, Peter, Oosten, Astrid W., Oomen—de Hoop, Esther, Koolen, Stijn L. W., Van der Rijt, Carin C. D., Mathijssen, Ron H. J.
Publicado 2018

Influence of Genetic Variation in COMT on Cisplatin-Induced Nephrotoxicity in Cancer Patients

por Agema, Bram C., Koolen, Stijn L.W., de With, Mirjam, van Doorn, Nadia, Heersche, Niels, Oomen-de Hoop, Esther, Visser, Sabine, Aerts, Joachim G.J.V., Bins, Sander, van Schaik, Ron H.N., Mathijssen, Ron H.J.
Publicado 2020

In Vivo Efficacy Testing of Peptide Receptor Radionuclide Therapy Radiosensitization Using Olaparib

por Feijtel, Danny, Reuvers, Thom G. A., van Tuyll-van Serooskerken, Christine, de Ridder, Corrina M. A., Stuurman, Debra C., de Blois, Erik, Verkaik, Nicole S., de Bruijn, Peter, Koolen, Stijn L. W., de Jong, Marion, Nonnekens, Julie
Publicado 2023

Improving the tolerability of osimertinib by identifying its toxic limit

por Agema, Bram C., Veerman, G. D. Marijn, Steendam, Christi M. J., Lanser, Daan A. C., Preijers, Tim, van der Leest, Cor, Koch, Birgit C. P., Dingemans, Anne-Marie C., Mathijssen, Ron H. J., Koolen, Stijn L. W.
Publicado 2022

Radiolabeling and quality control of therapeutic radiopharmaceuticals: optimization, clinical implementation and comparison of radio-TLC/HPLC analysis, demonstrated by [(177)Lu]Lu-...

por Hooijman, Eline L., Ntihabose, Carolline M., Reuvers, Thom G. A., Nonnekens, Julie, Aalbersberg, Else A., van de Merbel, Jordy R. J. P., Huijmans, Judith E., Koolen, Stijn L. W., Hendrikx, Jeroen J. M. A., de Blois, Erik
Publicado 2022