A role for BCL2L13 and autophagy in germline purifying selection of mtDNA

por Kremer, Laura S., Bozhilova, Lyuba V., Rubalcava-Gracia, Diana, Filograna, Roberta, Upadhyay, Mamta, Koolmeister, Camilla, Chinnery, Patrick F., Larsson, Nils-Göran
Publicado 2023

The amino terminal extension of mammalian mitochondrial RNA polymerase ensures promoter specific transcription initiation

por Posse, Viktor, Hoberg, Emily, Dierckx, Anke, Shahzad, Saba, Koolmeister, Camilla, Larsson, Nils-Göran, Wilhelmsson, L. Marcus, Hällberg, B. Martin, Gustafsson, Claes M.
Publicado 2014

High levels of TFAM repress mammalian mitochondrial DNA transcription in vivo

por Bonekamp, Nina A, Jiang, Min, Motori, Elisa, Garcia Villegas, Rodolfo, Koolmeister, Camilla, Atanassov, Ilian, Mesaros, Andrea, Park, Chan Bae, Larsson, Nils-Göran
Publicado 2021

FBXL4 deficiency increases mitochondrial removal by autophagy

por Alsina, David, Lytovchenko, Oleksandr, Schab, Aleksandra, Atanassov, Ilian, Schober, Florian A, Jiang, Min, Koolmeister, Camilla, Wedell, Anna, Taylor, Robert W, Wredenberg, Anna, Larsson, Nils‐Göran
Publicado 2020

Mitochondrial dysfunction in adult midbrain dopamine neurons triggers an early immune response

por Filograna, Roberta, Lee, Seungmin, Tiklová, Katarína, Mennuni, Mara, Jonsson, Viktor, Ringnér, Markus, Gillberg, Linda, Sopova, Elena, Shupliakov, Oleg, Koolmeister, Camilla, Olson, Lars, Perlmann, Thomas, Larsson, Nils-Göran
Publicado 2021

Variation in germ line mtDNA heteroplasmy is determined prenatally but modified during subsequent transmission

por Freyer, Christoph, Cree, Lynsey M., Mourier, Arnaud, Stewart, James B., Koolmeister, Camilla, Milenkovic, Dusanka, Wai, Timothy, Floros, Vasileios I., Hagström, Erik, Chatzidaki, Emmanouella E., Wiesner, Rudolph J., Samuels, David C, Larsson, Nils-Göran, Chinnery, Patrick F.
Publicado 2012

Dinucleotide Degradation by REXO2 Maintains Promoter Specificity in Mammalian Mitochondria

por Nicholls, Thomas J., Spåhr, Henrik, Jiang, Shan, Siira, Stefan J., Koolmeister, Camilla, Sharma, Sushma, Kauppila, Johanna H.K., Jiang, Min, Kaever, Volkhard, Rackham, Oliver, Chabes, Andrei, Falkenberg, Maria, Filipovska, Aleksandra, Larsson, Nils-Göran, Gustafsson, Claes M.
Publicado 2019

TEFM regulates both transcription elongation and RNA processing in mitochondria

por Jiang, Shan, Koolmeister, Camilla, Misic, Jelena, Siira, Stefan, Kühl, Inge, Silva Ramos, Eduardo, Miranda, Maria, Jiang, Min, Posse, Viktor, Lytovchenko, Oleksandr, Atanassov, Ilian, Schober, Florian A, Wibom, Rolf, Hultenby, Kjell, Milenkovic, Dusanka, Gustafsson, Claes M, Filipovska, Aleksandra, Larsson, Nils‐Göran
Publicado 2019

Mammalian RNase H1 directs RNA primer formation for mtDNA replication initiation and is also necessary for mtDNA replication completion

por Misic, Jelena, Milenkovic, Dusanka, Al-Behadili, Ali, Xie, Xie, Jiang, Min, Jiang, Shan, Filograna, Roberta, Koolmeister, Camilla, Siira, Stefan J, Jenninger, Louise, Filipovska, Aleksandra, Clausen, Anders R, Caporali, Leonardo, Valentino, Maria Lucia, La Morgia, Chiara, Carelli, Valerio, Nicholls, Thomas J, Wredenberg, Anna, Falkenberg, Maria, Larsson, Nils-Göran
Publicado 2022

Antigen receptor stimulation induces purifying selection against pathogenic mitochondrial tRNA mutations

por Zhang, Jingdian, Koolmeister, Camilla, Han, Jinming, Filograna, Roberta, Hanke, Leo, Àdori, Monika, Sheward, Daniel J., Teifel, Sina, Gopalakrishna, Shreekara, Shao, Qiuya, Liu, Yong, Zhu, Keying, Harris, Robert A., McInerney, Gerald, Murrell, Ben, Aoun, Mike, Bäckdahl, Liselotte, Holmdahl, Rikard, Pekalski, Marcin, Wedell, Anna, Engvall, Martin, Wredenberg, Anna, Karlsson Hedestam, Gunilla B., Castro Dopico, Xaquin, Rorbach, Joanna
Publicado 2023