Using quantitative proteomic analysis to understand genotype specific intrinsic drug resistance in melanoma

por Koomen, John M., Smalley, Keiran S. M.
Publicado 2011

Parametric Power Spectral Density Analysis of Noise from Instrumentation in MALDI TOF Mass Spectrometry

por Shin, Hyunjin, Mutlu, Miray, Koomen, John M., Markey, Mia K.
Publicado 2007

Understanding the characteristics of mass spectrometry data through the use of simulation

por Coombes, Kevin R., Koomen, John M., Baggerly, Keith A., Morris, Jeffrey S., Kobayashi, Ryuji
Publicado 2007

Cdc45 Limits Replicon Usage from a Low Density of preRCs in Mammalian Cells

por Wong, Philip G., Winter, Sherry L., Zaika, Elena, Cao, Thinh V., Oguz, Umut, Koomen, John M., Hamlin, Joyce L., Alexandrow, Mark G.
Publicado 2011

GMSimpute: a generalized two-step Lasso approach to impute missing values in label-free mass spectrum analysis

por Li, Qian, Fisher, Kate, Meng, Wenjun, Fang, Bin, Welsh, Eric, Haura, Eric B, Koomen, John M, Eschrich, Steven A, Fridley, Brooke L, Chen, Y Ann
Publicado 2020

Multi-Omics and Informatics Analysis of FFPE Tissues Derived from Melanoma Patients with Long/Short Responses to Anti-PD1 Therapy Reveals Pathways of Response

por Garg, Saurabh K., Welsh, Eric A., Fang, Bin, Hernandez, Yuliana I., Rose, Trevor, Gray, Jhanelle, Koomen, John M., Berglund, Anders, Mulé, James J., Markowitz, Joseph
Publicado 2020

Activity-Based Proteomics Reveals Heterogeneous Kinome and ATP-Binding Proteome Responses to MEK Inhibition in KRAS Mutant Lung Cancer

por Kim, Jae-Young, Stewart, Paul A., Borne, Adam L., Fang, Bin, Welsh, Eric A., Chen, Yian Ann, Eschrich, Steven A., Koomen, John M., Haura, Eric B.
Publicado 2016

Inhibition of Shp2 suppresses mutant EGFR-induced lung tumors in transgenic mouse model of lung adenocarcinoma

por Schneeberger, Valentina E., Ren, Yuan, Luetteke, Noreen, Huang, Qingling, Chen, Liwei, Lawrence, Harshani R., Lawrence, Nicholas J., Haura, Eric B., Koomen, John M., Coppola, Domenico, Wu, Jie
Publicado 2015

A Pilot Proteogenomic Study with Data Integration Identifies MCT1 and GLUT1 as Prognostic Markers in Lung Adenocarcinoma

por Stewart, Paul A., Parapatics, Katja, Welsh, Eric A., Müller, André C., Cao, Haoyun, Fang, Bin, Koomen, John M., Eschrich, Steven A., Bennett, Keiryn L., Haura, Eric B.
Publicado 2015

Integrated proteomics identifies PARP inhibitor-induced prosurvival signaling changes as potential vulnerabilities in ovarian cancer

por Deng, Ou, Dash, Sweta, Nepomuceno, Thales C., Fang, Bin, Yun, Sang Y., Welsh, Eric A., Lawrence, Harshani R., Marchion, Douglas, Koomen, John M., Monteiro, Alvaro N., Rix, Uwe
Publicado 2022

A comparative Proteomics Analysis Identified Differentially Expressed Proteins in Pancreatic Cancer–Associated Stellate Cell Small Extracellular Vesicles

por Sarcar, Bhaswati, Fang, Bin, Izumi, Victoria, O. Nunez Lopez, Yury, Tassielli, Alexandra, Pratley, Richard, Jeong, Daniel, Permuth, Jennifer B., Koomen, John M., Fleming, Jason B., Stewart, Paul A.
Publicado 2022

Chronic acidosis in the tumour microenvironment selects for overexpression of LAMP2 in the plasma membrane

por Damaghi, Mehdi, Tafreshi, Narges K., Lloyd, Mark C., Sprung, Robert, Estrella, Veronica, Wojtkowiak, Jonathan W., Morse, David L., Koomen, John M., Bui, Marilyn M., Gatenby, Robert A, Gillies, Robert J
Publicado 2015

Metabolomics of primary cutaneous melanoma and matched adjacent extratumoral microenvironment

por Taylor, Nicholas J., Gaynanova, Irina, Eschrich, Steven A., Welsh, Eric A., Garrett, Timothy J., Beecher, Chris, Sharma, Ritin, Koomen, John M., Smalley, Keiran S. M., Messina, Jane L., Kanetsky, Peter A.
Publicado 2020

Macrophages Use Apoptotic Cell-Derived Methionine and DNMT3A During Efferocytosis to Promote Tissue Resolution

por Ampomah, Patrick B., Cai, Bishuang, Sukka, Santosh R., Gerlach, Brennan D., Yurdagul, Arif, Wang, Xiaobo, Kuriakose, George, Darville, Lancia N.F., Sun, Yan, Sidoli, Simone, Koomen, John M., Tall, Alan R., Tabas, Ira
Publicado 2022

TCR-Independent Metabolic Reprogramming Precedes Lymphoma-Driven Changes in T-cell Fate

por Hesterberg, Rebecca S., Liu, Min, Elmarsafawi, Aya G., Koomen, John M., Welsh, Eric A., Hesterberg, Stephen G., Ranatunga, Sujeewa, Yang, Chunying, Li, Weimin, Lawrence, Harshani R., Rodriguez, Paulo C., Berglund, Anders E., Cleveland, John L.
Publicado 2022

K27-linked ubiquitination of BRAF by ITCH engages cytokine response to maintain MEK-ERK signaling

por Yin, Qing, Han, Tao, Fang, Bin, Zhang, Guolin, Zhang, Chao, Roberts, Evan R., Izumi, Victoria, Zheng, Mengmeng, Jiang, Shulong, Yin, Xiu, Kim, Minjung, Cai, Jianfeng, Haura, Eric B., Koomen, John M., Smalley, Keiran S. M., Wan, Lixin
Publicado 2019

Inhibition of PI3K/Akt/mTOR signaling in PI3KR2-overexpressing colon cancer stem cells reduces tumor growth due to apoptosis

por Chen, Sugong, Fisher, Robert C., Signs, Steven, Molina, L. Alex, Shenoy, Anitha K., Lopez, Maria-Cecilia, Baker, Henry V., Koomen, John M., Chen, Yi, Gittleman, Haley, Barnholtz-Sloan, Jill, Berg, Annamarie, Appelman, Henry D., Huang, Emina H.
Publicado 2016

Detectable Lipidomes and Metabolomes by Different Plasma Exosome Isolation Methods in Healthy Controls and Patients with Advanced Prostate and Lung Cancer

por Soupir, Alex C., Tian, Yijun, Stewart, Paul A., Nunez-Lopez, Yury O., Manley, Brandon J., Pellini, Bruna, Bloomer, Amanda M., Zhang, Jingsong, Mo, Qianxing, Marchion, Douglas C., Liu, Min, Koomen, John M., Siegel, Erin M., Wang, Liang
Publicado 2023

GSK3β inhibition blocks melanoma cell/host interactions by downregulating N-cadherin expression and decreasing FAK phosphorylation

por John, Jobin K., Paraiso, Kim H.T., Rebecca, Vito W., Cantini, Liliana P., Abel, Ethan V., Pagano, Nicholas, Meggers, Eric, Mathew, Rahel, Krepler, Clemens, Izumi, Victoria, Fang, Bin, Koomen, John M., Messina, Jane L., Herlyn, Meenhard, Smalley, Keiran S. M.
Publicado 2012

Disrupting the MYC-TFEB Circuit Impairs Amino Acid Homeostasis and Provokes Metabolic Anergy

por Fernandez, Mario R., Schaub, Franz X., Yang, Chunying, Li, Weimin, Yun, Seongseok, Schaub, Stephanie K., Dorsey, Frank C., Liu, Min, Steeves, Meredith A., Ballabio, Andrea, Tzankov, Alexandar, Chen, Zhihua, Koomen, John M., Berglund, Anders E., Cleveland, John L.
Publicado 2022