Emerging Roles of Gut Microbial Modulation of Bile Acid Composition in the Etiology of Cardiovascular Diseases

por Yntema, Tess, Koonen, Debby P. Y., Kuipers, Folkert
Publicado 2023

5-aminosalicylic acid improves lipid profile in mice fed a high-fat cholesterol diet through its dual effects on intestinal PPARγ and PPARα

por Wang, Zheng, Koonen, Debby, Hofker, Marten, Bao, Zhijun
Publicado 2018

Retraction: 5-aminosalicylic acid improves lipid profile in mice fed a high-fat cholesterol diet through its dual effects on intestinal PPARγ and PPARα

por Wang, Zheng, Koonen, Debby, Hofker, Marten, Bao, Zhijun
Publicado 2018

Pharmacological myeloperoxidase (MPO) inhibition in an obese/hypertensive mouse model attenuates obesity and liver damage, but not cardiac remodeling

por Piek, Arnold, Koonen, Debby P. Y., Schouten, Elisabeth-Maria, Lindtstedt, Eva L., Michaëlsson, Erik, de Boer, Rudolf A., Silljé, Herman H. W.
Publicado 2019

Pharmacomicrobiomics: a novel route towards personalized medicine?

por Doestzada, Marwah, Vila, Arnau Vich, Zhernakova, Alexandra, Koonen, Debby P. Y., Weersma, Rinse K., Touw, Daan J., Kuipers, Folkert, Wijmenga, Cisca, Fu, Jingyuan
Publicado 2018

Hematopoietic Npc1 mutation shifts gut microbiota composition in Ldlr(−/−) mice on a high-fat, high-cholesterol diet

por Houben, Tom, Penders, John, Oligschlaeger, Yvonne, dos Reis, Inês A. Magro, Bonder, Marc-Jan, Koonen, Debby P., Fu, Jingyuan, Hofker, Marten H., Shiri-Sverdlov, Ronit
Publicado 2019

AKIP1 Expression Modulates Mitochondrial Function in Rat Neonatal Cardiomyocytes

por Yu, Hongjuan, Tigchelaar, Wardit, Koonen, Debby P. Y., Patel, Hemal H., de Boer, Rudolf A., van Gilst, Wiek H., Westenbrink, B. Daan, Silljé, Herman H. W.
Publicado 2013

Cholesterol-Induced Hepatic Inflammation Does Not Underlie the Predisposition to Insulin Resistance in Dyslipidemic Female LDL Receptor Knockout Mice

por Gruben, Nanda, Funke, Anouk, Kloosterhuis, Niels J., Schreurs, Marijke, Sheedfar, Fareeba, Havinga, Rick, Houten, Sander M., Shiri-Sverdlov, Ronit, van de Sluis, Bart, Kuivenhoven, Jan Albert, Koonen, Debby P. Y., Hofker, Marten H.
Publicado 2015

Effects of Anthocyanin and Flavanol Compounds on Lipid Metabolism and Adipose Tissue Associated Systemic Inflammation in Diet-Induced Obesity

por van der Heijden, Roel A., Morrison, Martine C., Sheedfar, Fareeba, Mulder, Petra, Schreurs, Marijke, Hommelberg, Pascal P. H., Hofker, Marten H., Schalkwijk, Casper, Kleemann, Robert, Tietge, Uwe J. F., Koonen, Debby P. Y., Heeringa, Peter
Publicado 2016

Chemokine-Like Receptor 1 Deficiency Does Not Affect the Development of Insulin Resistance and Nonalcoholic Fatty Liver Disease in Mice

por Gruben, Nanda, Aparicio Vergara, Marcela, Kloosterhuis, Niels J., van der Molen, Henk, Stoelwinder, Stefan, Youssef, Sameh, de Bruin, Alain, Delsing, Dianne J., Kuivenhoven, Jan Albert, van de Sluis, Bart, Hofker, Marten H., Koonen, Debby P. Y.
Publicado 2014

High-fat diet induced obesity primes inflammation in adipose tissue prior to liver in C57BL/6j mice

por van der Heijden, Roel A, Sheedfar, Fareeba, Morrison, Martine C, Hommelberg, Pascal PH, Kor, Danny, Kloosterhuis, Niels J, Gruben, Nanda, Youssef, Sameh A, de Bruin, Alain, Hofker, Marten H, Kleemann, Robert, Koonen, Debby PY, Heeringa, Peter
Publicado 2015

Alterations in Skeletal Muscle Fatty Acid Handling Predisposes Middle-Aged Mice to Diet-Induced Insulin Resistance

por Koonen, Debby P.Y., Sung, Miranda M.Y., Kao, Cindy K.C., Dolinsky, Vernon W., Koves, Timothy R., Ilkayeva, Olga, Jacobs, René L., Vance, Dennis E., Light, Peter E., Muoio, Deborah M., Febbraio, Maria, Dyck, Jason R.B.
Publicado 2010

Increased hepatic CD36 expression with age is associated with enhanced susceptibility to nonalcoholic fatty liver disease

por Sheedfar, Fareeba, Sung, Miranda MY, Aparicio-Vergara, Marcela, Kloosterhuis, Niels J, Miquilena-Colina, Maria Eugenia, Vargas-Castrillón, Javier, Febbraio, Maria, Jacobs, René L, de Bruin, Alain, Vinciguerra, Manlio, García-Monzón, Carmelo, Hofker, Marten H, Dyck, Jason RB, Koonen, Debby PY
Publicado 2014

The hepatocyte IKK:NF-κB axis promotes liver steatosis by stimulating de novo lipogenesis and cholesterol synthesis

por Heida, Andries, Gruben, Nanda, Catrysse, Leen, Koehorst, Martijn, Koster, Mirjam, Kloosterhuis, Niels J., Gerding, Albert, Havinga, Rick, Bloks, Vincent W., Bongiovanni, Laura, Wolters, Justina C., van Dijk, Theo, van Loo, Geert, de Bruin, Alain, Kuipers, Folkert, Koonen, Debby P.Y., van de Sluis, Bart
Publicado 2021

Dietary butyrate ameliorates metabolic health associated with selective proliferation of gut Lachnospiraceae bacterium 28-4

por Li, Zhuang, Zhou, Enchen, Liu, Cong, Wicks, Hope, Yildiz, Sena, Razack, Farhana, Ying, Zhixiong, Kooijman, Sander, Koonen, Debby P.Y., Heijink, Marieke, Kostidis, Sarantos, Giera, Martin, Sanders, Ingrid M.J.G., Kuijper, Ed J., Smits, Wiep Klaas, van Dijk, Ko Willems, Rensen, Patrick C.N., Wang, Yanan
Publicado 2023

A Proinflammatory Gut Microbiota Increases Systemic Inflammation and Accelerates Atherosclerosis

por Brandsma, Eelke, Kloosterhuis, Niels J., Koster, Mirjam, Dekker, Daphne C., Gijbels, Marion J.J., van der Velden, Saskia, Ríos-Morales, Melany, van Faassen, Martijn J.R., Loreti, Marco G., de Bruin, Alain, Fu, Jingyuan, Kuipers, Folkert, Bakker, Barbara M., Westerterp, Marit, de Winther, Menno P.J., Hofker, Marten H., van de Sluis, Bart, Koonen, Debby P.Y.
Publicado 2019