Tissue inhibitor of metalloproteinases-1-induced scattered liver metastasis is mediated by host-derived urokinase-type plasminogen activator

por Schrötzlmair, Florian, Kopitz, Charlotte, Halbgewachs, Birgit, Lu, Fei, Algül, Hana, Brünner, Nils, Gänsbacher, Bernd, Krüger, Achim
Publicado 2010

Knockdown of platinum-induced growth differentiation factor 15 abrogates p27-mediated tumor growth delay in the chemoresistant ovarian cancer model A2780cis

por Meier, Julia C, Haendler, Bernard, Seidel, Henrik, Groth, Philip, Adams, Robert, Ziegelbauer, Karl, Kreft, Bertolt, Beckmann, Georg, Sommer, Anette, Kopitz, Charlotte
Publicado 2015

A Small Molecule–Drug Conjugate (SMDC) Consisting of a Modified Camptothecin Payload Linked to an α(V)ß(3) Binder for the Treatment of Multiple Cancer Types

por Lerchen, Hans-Georg, Stelte-Ludwig, Beatrix, Kopitz, Charlotte, Heroult, Melanie, Zubov, Dmitry, Willuda, Joerg, Schlange, Thomas, Kahnert, Antje, Wong, Harvey, Izumi, Raquel, Hamdy, Ahmed
Publicado 2022

Targeting mitochondrial complex I using BAY 87-2243 reduces melanoma tumor growth

por Schöckel, Laura, Glasauer, Andrea, Basit, Farhan, Bitschar, Katharina, Truong, Hoa, Erdmann, Gerrit, Algire, Carolyn, Hägebarth, Andrea, Willems, Peter HGM, Kopitz, Charlotte, Koopman, Werner JH, Héroult, Mélanie
Publicado 2015

Mitochondrial complex I inhibition triggers a mitophagy-dependent ROS increase leading to necroptosis and ferroptosis in melanoma cells

por Basit, Farhan, van Oppen, Lisanne MPE, Schöckel, Laura, Bossenbroek, Hasse M, van Emst-de Vries, Sjenet E, Hermeling, Johannes CW, Grefte, Sander, Kopitz, Charlotte, Heroult, Melanie, HGM Willems, Peter, Koopman, Werner JH
Publicado 2017

Rogaratinib: A potent and selective pan‐FGFR inhibitor with broad antitumor activity in FGFR‐overexpressing preclinical cancer models

por Grünewald, Sylvia, Politz, Oliver, Bender, Sebastian, Héroult, Mélanie, Lustig, Klemens, Thuss, Uwe, Kneip, Christoph, Kopitz, Charlotte, Zopf, Dieter, Collin, Marie‐Pierre, Boemer, Ulf, Ince, Stuart, Ellinghaus, Peter, Mumberg, Dominik, Hess‐Stumpp, Holger, Ziegelbauer, Karl
Publicado 2019

Evidence for an alternative fatty acid desaturation pathway increasing cancer plasticity

por Vriens, Kim, Christe, Stefan, Parik, Sweta, Broekaert, Dorien, Yoshinaga, Kazuaki, Talebi, Ali, Dehairs, Jonas, Escalona-Noguero, Carmen, Schmieder, Roberta, Cornfield, Thomas, Charlton, Catriona, Romero-Pérez, Laura, Rossi, Matteo, Rinaldi, Gianmarco, Orth, Martin F., Boon, Ruben, Kerstens, Axelle, Kwan, Suet Ying, Faubert, Brandon, Méndez-Lucas, Andrés, Kopitz, Charlotte C., Chen, Ting, Fernandez-Garcia, Juan, Duarte, João A.G., Schmitz, Arndt A., Steigemann, Patrick, Najimi, Mustapha, Hägebarth, Andrea, Van Ginderachter, Jo A., Sokal, Etienne, Gotoh, Naohiro, Wong, Kwok-Kin, Verfaillie, Catherine, Derua, Rita, Munck, Sebastian, Yuneva, Mariia, Beretta, Laura, DeBerardinis, Ralph J., Swinnen, Johannes V., Hodson, Leanne, Cassiman, David, Verslype, Chris, Christian, Sven, Grünewald, Sylvia, Grünewald, Thomas G.P., Fendt, Sarah-Maria
Publicado 2019