An unexpected link between fatty acid synthase and cholesterol synthesis in proinflammatory macrophage activation

por Carroll, Richard G., Zasłona, Zbigniew, Galván-Peña, Silvia, Koppe, Emma L., Sévin, Daniel C., Angiari, Stefano, Triantafilou, Martha, Triantafilou, Kathy, Modis, Louise K., O'Neill, Luke A.
Publicado 2018

Human rhinovirus promotes STING trafficking to replication organelles to promote viral replication

por Triantafilou, Martha, Ramanjulu, Joshi, Booty, Lee M., Jimenez-Duran, Gisela, Keles, Hakan, Saunders, Ken, Nevins, Neysa, Koppe, Emma, Modis, Louise K., Pesiridis, G. Scott, Bertin, John, Triantafilou, Kathy
Publicado 2022

Autoantigen TRIM21/Ro52 is expressed on the surface of antigen-presenting cells and its enhanced expression in Sjögren’s syndrome is associated with B cell hyperactivity and type I...

por Hillen, Maarten R, Urso, Katia, Koppe, Emma, Lopes, Ana Pinheiro, Blokland, Sofie L M, Pandit, Aridaman, Slocombe, Tom, van Maurik, André, van Roon, Joel A G, Radstake, Timothy R D J
Publicado 2020

Differential recognition of HIV-stimulated IL-1β and IL-18 secretion through NLR and NAIP signalling in monocyte-derived macrophages

por Triantafilou, Kathy, Ward, Christopher J. K., Czubala, Magdalena, Ferris, Robert G., Koppe, Emma, Haffner, Curt, Piguet, Vincent, Patel, Vipulkumar K., Amrine-Madsen, Heather, Modis, Louise K., Masters, Seth L., Triantafilou, Martha
Publicado 2021

Pharmacological validation of targets regulating CD14 during macrophage differentiation

por Jimenez-Duran, Gisela, Luque-Martin, Rosario, Patel, Meghana, Koppe, Emma, Bernard, Sharon, Sharp, Catriona, Buchan, Natalie, Rea, Ceara, de Winther, Menno P.J., Turan, Nil, Angell, Davina, Wells, Christine A., Cousins, Rick, Mander, Palwinder K., Masters, Seth L.
Publicado 2020

In silico and in vitro evaluation of exonic and intronic off-target effects form a critical element of therapeutic ASO gapmer optimization

por Kamola, Piotr J., Kitson, Jeremy D. A., Turner, Gemma, Maratou, Klio, Eriksson, Sofie, Panjwani, Aliza, Warnock, Linda C., Douillard Guilloux, Gaelle A., Moores, Kitty, Koppe, Emma L., Wixted, William E., Wilson, Paul A., Gooderham, Nigel J., Gant, Timothy W., Clark, Kenneth L., Hughes, Stephen A., Edbrooke, Mark R., Parry, Joel D.
Publicado 2015

Improving the efficiency and effectiveness of an industrial SARS-CoV-2 diagnostic facility

por Douthwaite, Julie A., Brown, Christopher A., Ferdinand, John R., Sharma, Rahul, Elliott, Jane, Taylor, Molly A., Malintan, Nancy T., Duvoisin, Hannah, Hill, Thomas, Delpuech, Oona, Orton, Alexandra L., Pitt, Haidee, Kuenzi, Fred, Fish, Simon, Nicholls, David J., Cuthbert, Anna, Richards, Ian, Ratcliffe, Giles, Upadhyay, Abhishek, Marklew, Abigail, Hewitt, Craig, Ross-Thriepland, Douglas, Brankin, Christopher, Chodorge, Matthieu, Browne, Gareth, Mander, Palwinder K., DeWildt, Ruud M., Weaver, Shane, Smee, Penny A., van Kempen, Joost, Bartlett, Jon G., Allen, Paula M., Koppe, Emma L., Ashby, Charlotte A., Phipps, Julian D., Mehta, Nalini, Brierley, David J., Tew, David G., Leveridge, Melanie V., Baddeley, Stuart M., Goodfellow, Ian G., Green, Clive, Abell, Chris, Neely, Andy, Waddell, Ian, Rees, Steve, Maxwell, Patrick H., Pangalos, Menelas N., Howes, Rob, Clark, Roger
Publicado 2022