A historical review of multiple system atrophy with a critical appraisal of cellular and animal models

por Marmion, David J., Peelaerts, Wouter, Kordower, Jeffrey H.
Publicado 2021

Aging and Parkinson’s Disease: Different Sides of the Same Coin?

por Collier, Timothy J., Kanaan, Nicholas M., Kordower, Jeffrey H.
Publicado 2017

Endogenous alpha-synuclein monomers, oligomers and resulting pathology: let’s talk about the lipids in the room

por Killinger, Bryan A., Melki, Ronald, Brundin, Patrik, Kordower, Jeffrey H.
Publicado 2019

Non-Chromaffin Cell Constituents of the Adrenal Medulla are Detrimental to the Survival of Grafted Adrenal Chromaffin Cells: Studies in Rats and Non-Human Primates

por Schueler, Sherry B., Ortega, John D., Sagen, Jacqueline, Kordower, Jeffrey H.
Publicado 1992

Long-term post-mortem studies following neurturin gene therapy in patients with advanced Parkinson’s disease

por Chu, Yaping, Bartus, Raymond T, Manfredsson, Fredric P, Olanow, C Warren, Kordower, Jeffrey H
Publicado 2020

Does Developmental Variability in the Number of Midbrain Dopamine Neurons Affect Individual Risk for Sporadic Parkinson’s Disease?

por von Linstow, Christian U., DeLano-Taylor, Merritt, Kordower, Jeffrey H., Brundin, Patrik
Publicado 2020

Long-term, stable, targeted biodelivery and efficacy of GDNF from encapsulated cells in the rat and Goettingen miniature pig brain

por Wahlberg, Lars U., Emerich, Dwaine F., Kordower, Jeffrey H., Bell, William, Fradet, Tracie, Paolone, Giovanna
Publicado 2020

Distribution of phosphorylated alpha-synuclein in non-diseased brain implicates olfactory bulb mitral cells in synucleinopathy pathogenesis

por Killinger, Bryan A., Mercado, Gabriela, Choi, Solji, Tittle, Tyler, Chu, Yaping, Brundin, Patrik, Kordower, Jeffrey H.
Publicado 2023

Continuous DOPA synthesis from a single AAV: dosing and efficacy in models of Parkinson's disease

por Cederfjäll, Erik, Nilsson, Nathalie, Sahin, Gurdal, Chu, Yaping, Nikitidou, Elisabeth, Björklund, Tomas, Kordower, Jeffrey H., Kirik, Deniz
Publicado 2013

Proteasome-targeted nanobodies alleviate pathology and functional decline in an α-synuclein-based Parkinson’s disease model

por Chatterjee, Diptaman, Bhatt, Mansi, Butler, David, De Genst, Erwin, Dobson, Christopher M., Messer, Anne, Kordower, Jeffrey H.
Publicado 2018

Widespread Striatal Delivery of GDNF from Encapsulated Cells Prevents the Anatomical and Functional Consequences of Excitotoxicity

por Emerich, Dwaine F., Kordower, Jeffrey H., Chu, Yaping, Thanos, Chris, Bintz, Briannan, Paolone, Giovanna, Wahlberg, Lars U.
Publicado 2019

SeqStain is an efficient method for multiplexed, spatialomic profiling of human and murine tissues

por Rajagopalan, Anugraha, Venkatesh, Ishwarya, Aslam, Rabail, Kirchenbuechler, David, Khanna, Shreyaa, Cimbaluk, David, Kordower, Jeffrey H., Gupta, Vineet
Publicado 2021

In situ proximity labeling identifies Lewy pathology molecular interactions in the human brain

por Killinger, Bryan A., Marshall, Lee L., Chatterjee, Diptaman, Chu, Yaping, Bras, Jose, Guerreiro, Rita, Kordower, Jeffrey H.
Publicado 2022

Enhanced CNS transduction from AAV.PHP.eB infusion into the cisterna magna of older adult rats compared to AAV9

por Chatterjee, Diptaman, Marmion, David J., McBride, Jodi L., Manfredsson, Fredric P., Butler, David, Messer, Anne, Kordower, Jeffrey H.
Publicado 2021

Neither alpha-synuclein-preformed fibrils derived from patients with GBA1 mutations nor the host murine genotype significantly influence seeding efficacy in the mouse olfactory bul...

por Walton, Sara, Fenyi, Alexis, Tittle, Tyler, Sidransky, Ellen, Pal, Gian, Choi, Solji, Melki, Ronald, Killinger, Bryan A., Kordower, Jeffrey H.
Publicado 2023

Novel oligodendroglial alpha synuclein viral vector models of multiple system atrophy: studies in rodents and nonhuman primates

por Mandel, Ronald J., Marmion, David J., Kirik, Deniz, Chu, Yaping, Heindel, Clifford, McCown, Thomas, Gray, Steven J., Kordower, Jeffrey H.
Publicado 2017

PGC−1α Promoter Methylation in Parkinson’s Disease

por Su, Xiaomin, Chu, Yaping, Kordower, Jeffrey H., Li, Bin, Cao, Hong, Huang, Liang, Nishida, Maki, Song, Lei, Wang, Difei, Federoff, Howard J.
Publicado 2015

Evaluation of alpha-synuclein immunohistochemical methods for the detection of Lewy-type synucleinopathy in gastrointestinal biopsies

por Corbillé, Anne-Gaëlle, Letournel, Franck, Kordower, Jeffrey H., Lee, John, Shanes, Elisheva, Neunlist, Michel, Munoz, David G., Derkinderen, Pascal, Beach, Thomas G.
Publicado 2016

T cell infiltration in both human multiple system atrophy and a novel mouse model of the disease

por Williams, Gregory P., Marmion, David J., Schonhoff, Aubrey M., Jurkuvenaite, Asta, Won, Woong-Jai, Standaert, David G., Kordower, Jeffrey H., Harms, Ashley S.
Publicado 2020

A novel tau‐based rhesus monkey model of Alzheimer's pathogenesis

por Beckman, Danielle, Chakrabarty, Paramita, Ott, Sean, Dao, Amanda, Zhou, Eric, Janssen, William G., Donis‐Cox, Kristine, Muller, Scott, Kordower, Jeffrey H., Morrison, John H.
Publicado 2021