Combined Adipose Tissue-Derived Mesenchymal Stem Cell Therapy and Rehabilitation in Experimental Stroke

por Mu, Jingwei, Bakreen, Abdulhameed, Juntunen, Miia, Korhonen, Paula, Oinonen, Ella, Cui, Lili, Myllyniemi, Mikko, Zhao, Shanshan, Miettinen, Susanna, Jolkkonen, Jukka
Publicado 2019

Changes in nuclear and cytoplasmic microRNA distribution in response to hypoxic stress

por Turunen, Tiia A., Roberts, Thomas C., Laitinen, Pia, Väänänen, Mari-Anna, Korhonen, Paula, Malm, Tarja, Ylä-Herttuala, Seppo, Turunen, Mikko P.
Publicado 2019

Metabolomic and lipidomic changes triggered by lipopolysaccharide-induced systemic inflammation in transgenic APdE9 mice

por Puris, Elena, Kouřil, Štěpán, Najdekr, Lukáš, Loppi, Sanna, Korhonen, Paula, Kanninen, Katja M., Malm, Tarja, Koistinaho, Jari, Friedecký, David, Gynther, Mikko
Publicado 2021

Increased Expression and Activity of Brain Cortical cPLA2 Due to Chronic Lipopolysaccharide Administration in Mouse Model of Familial Alzheimer’s Disease

por Gynther, Mikko, Estrada, Mariana Leal, Loppi, Sanna, Korhonen, Paula, Kanninen, Katja M., Malm, Tarja, Koistinaho, Jari, Auriola, Seppo, Fricker, Gert, Puris, Elena
Publicado 2022

Functional Characterization of Human Pluripotent Stem Cell-Derived Models of the Brain with Microelectrode Arrays

por Pelkonen, Anssi, Pistono, Cristiana, Klecki, Pamela, Gómez-Budia, Mireia, Dougalis, Antonios, Konttinen, Henna, Stanová, Iveta, Fagerlund, Ilkka, Leinonen, Ville, Korhonen, Paula, Malm, Tarja
Publicado 2021

Inactivation of mouse transmembrane prolyl 4-hydroxylase increases blood brain barrier permeability and ischemia-induced cerebral neuroinflammation

por Byts, Nadiya, Sharma, Subodh, Malm, Tarja, Kaakinen, Mika, Korhonen, Paula, Jaakkonen, Laura, Keuters, Meike, Huuskonen, Mikko, Pietilä, Ilkka, Koistinaho, Jari, Koivunen, Peppi, Myllyharju, Johanna
Publicado 2022

Long-term interleukin-33 treatment delays disease onset and alleviates astrocytic activation in a transgenic mouse model of amyotrophic lateral sclerosis

por Korhonen, Paula, Pollari, Eveliina, Kanninen, Katja M., Savchenko, Ekaterina, Lehtonen, Šárka, Wojciechowski, Sara, Pomeshchik, Yuriy, Van Den Bosch, Ludo, Goldsteins, Gundars, Koistinaho, Jari, Malm, Tarja
Publicado 2019

Peripheral inflammatory markers and clinical correlations in patients with frontotemporal lobar degeneration with and without the C9orf72 repeat expansion

por Katisko, Kasper, Solje, Eino, Korhonen, Paula, Jääskeläinen, Olli, Loppi, Sanna, Hartikainen, Päivi, Koivisto, Anne M., Kontkanen, Aleksi, Korhonen, Ville E., Helisalmi, Seppo, Malm, Tarja, Herukka, Sanna-Kaisa, Remes, Anne M., Haapasalo, Annakaisa
Publicado 2019

Bexarotene targets autophagy and is protective against thromboembolic stroke in aged mice with tauopathy

por Huuskonen, Mikko T., Loppi, Sanna, Dhungana, Hiramani, Keksa-Goldsteine, Velta, Lemarchant, Sighild, Korhonen, Paula, Wojciechowski, Sara, Pollari, Eveliina, Valonen, Piia, Koponen, Juho, Takashima, Akihiko, Landreth, Gary, Goldsteins, Gundars, Malm, Tarja, Koistinaho, Jari, Kanninen, Katja M.
Publicado 2016

Intracerebral overexpression of miR-669c is protective in mouse ischemic stroke model by targeting MyD88 and inducing alternative microglial/macrophage activation

por Kolosowska, Natalia, Gotkiewicz, Maria, Dhungana, Hiramani, Giudice, Luca, Giugno, Rosalba, Box, Daphne, Huuskonen, Mikko T., Korhonen, Paula, Scoyni, Flavia, Kanninen, Katja M., Ylä-Herttuala, Seppo, Turunen, Tiia A., Turunen, Mikko P., Koistinaho, Jari, Malm, Tarja
Publicado 2020

Nuclear microRNA-466c regulates Vegfa expression in response to hypoxia

por Laitinen, Pia, Väänänen, Mari-Anna, Kolari, Ida-Liisa, Mäkinen, Petri I., Kaikkonen, Minna U., Weinberg, Marc S., Morris, Kevin V., Korhonen, Paula, Malm, Tarja, Ylä-Herttuala, Seppo, Roberts, Thomas C., Turunen, Mikko P., Turunen, Tiia A.
Publicado 2022

Urban air particulate matter induces mitochondrial dysfunction in human olfactory mucosal cells

por Chew, Sweelin, Lampinen, Riikka, Saveleva, Liudmila, Korhonen, Paula, Mikhailov, Nikita, Grubman, Alexandra, Polo, Jose M., Wilson, Trevor, Komppula, Mika, Rönkkö, Teemu, Gu, Cheng, Mackay-Sim, Alan, Malm, Tarja, White, Anthony R., Jalava, Pasi, Kanninen, Katja M.
Publicado 2020

Microglia-like Cells Promote Neuronal Functions in Cerebral Organoids

por Fagerlund, Ilkka, Dougalis, Antonios, Shakirzyanova, Anastasia, Gómez-Budia, Mireia, Pelkonen, Anssi, Konttinen, Henna, Ohtonen, Sohvi, Fazaludeen, Mohammad Feroze, Koskuvi, Marja, Kuusisto, Johanna, Hernández, Damián, Pebay, Alice, Koistinaho, Jari, Rauramaa, Tuomas, Lehtonen, Šárka, Korhonen, Paula, Malm, Tarja
Publicado 2021

An arylthiazyne derivative is a potent inhibitor of lipid peroxidation and ferroptosis providing neuroprotection in vitro and in vivo

por Keuters, Meike Hedwig, Keksa-Goldsteine, Velta, Dhungana, Hiramani, Huuskonen, Mikko T., Pomeshchik, Yuriy, Savchenko, Ekaterina, Korhonen, Paula K., Singh, Yajuvinder, Wojciechowski, Sara, Lehtonen, Šárka, Kanninen, Katja M., Malm, Tarja, Sirviö, Jouni, Muona, Anu, Koistinaho, Milla, Goldsteins, Gundars, Koistinaho, Jari
Publicado 2021

Peripheral inflammation preceeding ischemia impairs neuronal survival through mechanisms involving miR‐127 in aged animals

por Loppi, Sanna, Korhonen, Paula, Bouvy‐Liivrand, Maria, Caligola, Simone, Turunen, Tiia A., Turunen, Mikko P., Hernandez de Sande, Ana, Kołosowska, Natalia, Scoyni, Flavia, Rosell, Anna, García‐Berrocoso, Teresa, Lemarchant, Sighild, Dhungana, Hiramani, Montaner, Joan, Koistinaho, Jari, Kanninen, Katja M., Kaikkonen, Minna U., Giugno, Rosalba, Heinäniemi, Merja, Malm, Tarja
Publicado 2020

Microglial amyloid beta clearance is driven by PIEZO1 channels

por Jäntti, Henna, Sitnikova, Valeriia, Ishchenko, Yevheniia, Shakirzyanova, Anastasia, Giudice, Luca, Ugidos, Irene F., Gómez-Budia, Mireia, Korvenlaita, Nea, Ohtonen, Sohvi, Belaya, Irina, Fazaludeen, Feroze, Mikhailov, Nikita, Gotkiewicz, Maria, Ketola, Kirsi, Lehtonen, Šárka, Koistinaho, Jari, Kanninen, Katja M., Hernández, Damian, Pébay, Alice, Giugno, Rosalba, Korhonen, Paula, Giniatullin, Rashid, Malm, Tarja
Publicado 2022

Reduced binding of apoE4 to complement factor H promotes amyloid‐β oligomerization and neuroinflammation

por Chernyaeva, Larisa, Ratti, Giorgio, Teirilä, Laura, Fudo, Satoshi, Rankka, Uni, Pelkonen, Anssi, Korhonen, Paula, Leskinen, Katarzyna, Keskitalo, Salla, Salokas, Kari, Gkolfinopoulou, Christina, Crompton, Katrina E, Javanainen, Matti, Happonen, Lotta, Varjosalo, Markku, Malm, Tarja, Leinonen, Ville, Chroni, Angeliki, Saavalainen, Päivi, Meri, Seppo, Kajander, Tommi, Wollman, Adam JM, Nissilä, Eija, Haapasalo, Karita
Publicado 2023

Dynamic release of neuronal extracellular vesicles containing miR‐21a‐5p is induced by hypoxia

por Korvenlaita, Nea, Gómez‐Budia, Mireia, Scoyni, Flavia, Pistono, Cristiana, Giudice, Luca, Eamen, Shaila, Loppi, Sanna, de Sande, Ana Hernández, Huremagic, Benjamin, Bouvy‐Liivrand, Maria, Heinäniemi, Merja, Kaikkonen, Minna U., Cheng, Lesley, Hill, Andrew F., Kanninen, Katja M., Jenster, Guido W., van Royen, Martin E., Ramiro, Laura, Montaner, Joan, Batkova, Tereza, Mikulik, Robert, Giugno, Rosalba, Jolkkonen, Jukka, Korhonen, Paula, Malm, Tarja
Publicado 2023

PSEN1ΔE9, APPswe, and APOE4 Confer Disparate Phenotypes in Human iPSC-Derived Microglia

por Konttinen, Henna, Cabral-da-Silva, Mauricio e Castro, Ohtonen, Sohvi, Wojciechowski, Sara, Shakirzyanova, Anastasia, Caligola, Simone, Giugno, Rosalba, Ishchenko, Yevheniia, Hernández, Damián, Fazaludeen, Mohammad Feroze, Eamen, Shaila, Budia, Mireia Gómez, Fagerlund, Ilkka, Scoyni, Flavia, Korhonen, Paula, Huber, Nadine, Haapasalo, Annakaisa, Hewitt, Alex W., Vickers, James, Smith, Grady C., Oksanen, Minna, Graff, Caroline, Kanninen, Katja M., Lehtonen, Sarka, Propson, Nicholas, Schwartz, Michael P., Pébay, Alice, Koistinaho, Jari, Ooi, Lezanne, Malm, Tarja
Publicado 2019