Calculation of centralities in protein kinase A

por Kornev, Alexandr P., Aoto, Phillip C., Taylor, Susan S.
Publicado 2022

A Generalized Allosteric Mechanism for cis-Regulated Cyclic Nucleotide Binding Domains

por Kornev, Alexandr P., Taylor, Susan S., Ten Eyck, Lynn F.
Publicado 2008

Correction: A Generalized Allosteric Mechanism for cis-Regulated Cyclic Nucleotide Binding Domains

por Kornev, Alexandr P., Taylor, Susan S., Ten Eyck, Lynn F.
Publicado 2009

Evolution of the eukaryotic protein kinases as dynamic molecular switches

por Taylor, Susan S., Keshwani, Malik M., Steichen, Jon M., Kornev, Alexandr P.
Publicado 2012

Allostery through the computational microscope: cAMP activation of a canonical signaling domain

por Malmstrom, Robert D., Kornev, Alexandr P., Taylor, Susan S., Amaro, Rommie E.
Publicado 2015

PKA: assembly of dynamic macromolecular signaling

por Taylor, Susan S, Ilouz, Ronit, Darshi, Manjula, Sarma, Ganapathy, Kornev, Alexandr, Zhang, Ping
Publicado 2011

Single-residue mutation in protein kinase C toggles between cancer and neurodegeneration

por Jones, Alexander C., Kornev, Alexandr P., Weng, Jui-Hung, Manning, Gerard, Taylor, Susan S., Newton, Alexandra C.
Publicado 2023

Protein Kinase Structure and Dynamics: Role of the αC-β4 Loop

por Wu, Jian, Jonniya, Nisha A., Hirakis, Sophia P., Olivieri, Cristina, Veglia, Gianluigi, Kornev, Alexandr P., Taylor, Susan S.
Publicado 2023

Deciphering the Structural Basis of Eukaryotic Protein Kinase Regulation

por Meharena, Hiruy S., Chang, Philip, Keshwani, Malik M., Oruganty, Krishnadev, Nene, Aishwarya K., Kannan, Natarajan, Taylor, Susan S., Kornev, Alexandr P.
Publicado 2013

A dynamic hydrophobic core orchestrates allostery in protein kinases

por Kim, Jonggul, Ahuja, Lalima G., Chao, Fa-An, Xia, Youlin, McClendon, Christopher L., Kornev, Alexandr P., Taylor, Susan S., Veglia, Gianluigi
Publicado 2017

The dynamic switch mechanism that leads to activation of LRRK2 is embedded in the DFGψ motif in the kinase domain

por Schmidt, Sven H., Knape, Matthias J., Boassa, Daniela, Mumdey, Natascha, Kornev, Alexandr P., Ellisman, Mark H., Taylor, Susan S., Herberg, Friedrich W.
Publicado 2019

From structure to the dynamic regulation of a molecular switch: A journey over 3 decades

por Taylor, Susan S., Wu, Jian, Bruystens, Jessica G.H., Del Rio, Jason C., Lu, Tsan-Wen, Kornev, Alexandr P., Ten Eyck, Lynn F.
Publicado 2021

Congenital myasthenic syndrome due to mutations in MUSK suggests that the level of MuSK phosphorylation is crucial for governing synaptic structure

por Rodríguez Cruz, Pedro M., Cossins, Judith, Cheung, Jonathan, Maxwell, Susan, Jayawant, Sandeep, Herbst, Ruth, Waithe, Dominic, Kornev, Alexandr P., Palace, Jacqueline, Beeson, David
Publicado 2019