Cerebrospinal Fluid Hypocretin-1 (Orexin-A) Level Fluctuates with Season and Correlates with Day Length

por Boddum, Kim, Hansen, Mathias Hvidtfelt, Jennum, Poul Jørgen, Kornum, Birgitte Rahbek
Publicado 2016

DNMT1 regulates expression of MHC class I in post-mitotic neurons

por Gustafsson, Julie Ry, Katsioudi, Georgia, Degn, Matilda, Ejlerskov, Patrick, Issazadeh-Navikas, Shohreh, Kornum, Birgitte Rahbek
Publicado 2018

Monozygotic twins discordant for narcolepsy type 1 and multiple sclerosis

por Jennum, Poul J., Kornum, Birgitte R., Issa, Nadia M., Gammeltoft, Steen, Tommerup, Niels, Morling, Niels, Tümer, Zeynep, Knudsen, Stine
Publicado 2016

Molecular consequences of peripheral Influenza A infection on cell populations in the murine hypothalamus

por Lemcke, René, Egebjerg, Christine, Berendtsen, Nicolai T, Egerod, Kristoffer L, Thomsen, Allan R, Pers, Tune H, Christensen, Jan P, Kornum, Birgitte R
Publicado 2023

Human P2Y(11) Expression Level Affects Human P2X7 Receptor-Mediated Cell Death

por Dreisig, Karin, Sund, Louise, Dommer, Maja Wallentin, Kristensen, Nikolaj Pagh, Boddum, Kim, Viste, Rannveig, Fredholm, Simon, Odum, Niels, Jäättelä, Marja, Skov, Søren, Kornum, Birgitte R.
Publicado 2018

High nocturnal sleep fragmentation is associated with low T lymphocyte P2Y(11) protein levels in narcolepsy type 1

por Viste, Rannveig, Viken, Marte K, Lie, Benedicte A, Juvodden, Hilde T, Nordstrand, Sebjørg E H, Thorsby, Per M, Rootwelt, Terje, Kornum, Birgitte R, Knudsen-Heier, Stine
Publicado 2021

Multi-omics characterization of a diet-induced obese model of non-alcoholic steatohepatitis

por Ægidius, Helene M., Veidal, Sanne S., Feigh, Michael, Hallenborg, Philip, Puglia, Michele, Pers, Tune H., Vrang, Niels, Jelsing, Jacob, Kornum, Birgitte R., Blagoev, Blagoy, Rigbolt, Kristoffer T. G.
Publicado 2020

Pre-treatment of blood samples reveal normal blood hypocretin/orexin signal in narcolepsy type 1

por Ægidius, Helene M, Kruse, Lars, Christensen, Gitte L, Lorentzen, Marc P, Jørgensen, Niklas R, Moresco, Monica, Pizza, Fabio, Plazzi, Giuseppe, Jennum, Poul J, Kornum, Birgitte R
Publicado 2021

Increased muscle activity during sleep and more RBD symptoms in H1N1-(Pandemrix)-vaccinated narcolepsy type 1 patients compared with their non-narcoleptic siblings

por Viste, Rannveig, Follin, Louise F, Kornum, Birgitte R, Lie, Benedicte A, Viken, Marte K, Thorsby, Per M, Rootwelt, Terje, Christensen, Julie A E, Knudsen-Heier, Stine
Publicado 2022

The evolutionarily conserved miRNA-137 targets the neuropeptide hypocretin/orexin and modulates the wake to sleep ratio

por Holm, Anja, Possovre, Marie-Laure, Bandarabadi, Mojtaba, Moseholm, Kristine F., Justinussen, Jessica L., Bozic, Ivan, Lemcke, René, Arribat, Yoan, Amati, Francesca, Silahtaroglu, Asli, Juventin, Maxime, Adamantidis, Antoine, Tafti, Mehdi, Kornum, Birgitte R.
Publicado 2022

CD8(+) T cells from patients with narcolepsy and healthy controls recognize hypocretin neuron-specific antigens

por Pedersen, Natasja Wulff, Holm, Anja, Kristensen, Nikolaj Pagh, Bjerregaard, Anne-Mette, Bentzen, Amalie Kai, Marquard, Andrea Marion, Tamhane, Tripti, Burgdorf, Kristoffer Sølvsten, Ullum, Henrik, Jennum, Poul, Knudsen, Stine, Hadrup, Sine Reker, Kornum, Birgitte Rahbek
Publicado 2019

In vivo clonal expansion and phenotypes of hypocretin-specific CD4(+) T cells in narcolepsy patients and controls

por Jiang, Wei, Birtley, James R., Hung, Shu-Chen, Wang, Weiqi, Chiou, Shin-Heng, Macaubas, Claudia, Kornum, Birgitte, Tian, Lu, Huang, Huang, Adler, Lital, Weaver, Grant, Lu, Liying, Ilstad-Minnihan, Alexandra, Somasundaram, Sriram, Ayyangar, Sashi, Davis, Mark M., Stern, Lawrence J., Mellins, Elizabeth D.
Publicado 2019

Author Correction: In vivo clonal expansion and phenotypes of hypocretin-specific CD4(+) T cells in narcolepsy patients and controls

por Jiang, Wei, Birtley, James R., Hung, Shu-Chen, Wang, Weiqi, Chiou, Shin-Heng, Macaubas, Claudia, Kornum, Birgitte, Tian, Lu, Huang, Huang, Adler, Lital, Weaver, Grant, Lu, Liying, Ilstad-Minnihan, Alexandra, Somasundaram, Sriram, Ayyangar, Sashi, Davis, Mark M., Stern, Lawrence J., Mellins, Elizabeth D.
Publicado 2020

Production of human entorhinal stellate cell-like cells by forward programming shows an important role of Foxp1 in reprogramming

por Bergmann, Tobias, Liu, Yong, Skov, Jonathan, Mogus, Leo, Lee, Julie, Pfisterer, Ulrich, Handfield, Louis-Francois, Asenjo-Martinez, Andrea, Lisa-Vargas, Irene, Seemann, Stefan E., Lee, Jimmy Tsz Hang, Patikas, Nikolaos, Kornum, Birgitte Rahbek, Denham, Mark, Hyttel, Poul, Witter, Menno P., Gorodkin, Jan, Pers, Tune H., Hemberg, Martin, Khodosevich, Konstantin, Hall, Vanessa Jane
Publicado 2022

Transcriptomic analysis links diverse hypothalamic cell types to fibroblast growth factor 1-induced sustained diabetes remission

por Bentsen, Marie A., Rausch, Dylan M., Mirzadeh, Zaman, Muta, Kenjiro, Scarlett, Jarrad M., Brown, Jenny M., Herranz-Pérez, Vicente, Baquero, Arian F., Thompson, Jonatan, Alonge, Kimberly M., Faber, Chelsea L., Kaiyala, Karl J., Bennett, Camdin, Pyke, Charles, Ratner, Cecilia, Egerod, Kristoffer L., Holst, Birgitte, Meek, Thomas H., Kutlu, Burak, Zhang, Yu, Sparso, Thomas, Grove, Kevin L., Morton, Gregory J., Kornum, Birgitte R., García-Verdugo, José-Manuel, Secher, Anna, Jorgensen, Rasmus, Schwartz, Michael W., Pers, Tune H.
Publicado 2020

GHB analogs confer neuroprotection through specific interaction with the CaMKIIα hub domain

por Leurs, Ulrike, Klein, Anders B., McSpadden, Ethan D., Griem-Krey, Nane, Solbak, Sara M. Ø., Houlton, Josh, Villumsen, Inge S., Vogensen, Stine B., Hamborg, Louise, Gauger, Stine J., Palmelund, Line B., Larsen, Anne Sofie G., Shehata, Mohamed A., Kelstrup, Christian D., Olsen, Jesper V., Bach, Anders, Burnie, Robert O., Kerr, D. Steven, Gowing, Emma K., Teurlings, Selina M. W., Chi, Chris C., Gee, Christine L., Frølund, Bente, Kornum, Birgitte R., van Woerden, Geeske M., Clausen, Rasmus P., Kuriyan, John, Clarkson, Andrew N., Wellendorph, Petrine
Publicado 2021

ImmunoChip Study Implicates Antigen Presentation to T Cells in Narcolepsy

por Faraco, Juliette, Lin, Ling, Kornum, Birgitte Rahbek, Kenny, Eimear E., Trynka, Gosia, Einen, Mali, Rico, Tom J., Lichtner, Peter, Dauvilliers, Yves, Arnulf, Isabelle, Lecendreux, Michel, Javidi, Sirous, Geisler, Peter, Mayer, Geert, Pizza, Fabio, Poli, Francesca, Plazzi, Giuseppe, Overeem, Sebastiaan, Lammers, Gert Jan, Kemlink, David, Sonka, Karel, Nevsimalova, Sona, Rouleau, Guy, Desautels, Alex, Montplaisir, Jacques, Frauscher, Birgit, Ehrmann, Laura, Högl, Birgit, Jennum, Poul, Bourgin, Patrice, Peraita-Adrados, Rosa, Iranzo, Alex, Bassetti, Claudio, Chen, Wei-Min, Concannon, Patrick, Thompson, Susan D., Damotte, Vincent, Fontaine, Bertrand, Breban, Maxime, Gieger, Christian, Klopp, Norman, Deloukas, Panos, Wijmenga, Cisca, Hallmayer, Joachim, Onengut-Gumuscu, Suna, Rich, Stephen S., Winkelmann, Juliane, Mignot, Emmanuel
Publicado 2013

Common variants in P2RY11 are associated with narcolepsy

por Kornum, Birgitte R, Kawashima, Minae, Faraco, Juliette, Lin, Ling, Rico, Tom, Hesselson, Stephanie, Axtell, Robert C, Kuipers, Hedwich, Weiner, Karin, Hamacher, Alexandra, Kassack, Matthias U, Han, Fang, Knudsen, Stine, Li, Jing, Dong, Xiaosong, Winkelmann, Juliane, Plazzi, Giuseppe, Nevsimalova, Sona, Hong, Seung-Chul, Honda, Yutaka, Honda, Makoto, Hogl, Birgit, Ton, Thanh G N, Montplaisir, Jacques, Bourgin, Patrice, Kemlink, David, Huang, Yu-Shu, Warby, Simon, Einen, Mali, Eshragh, Jasmin L, Miyagawa, Taku, Desautels, Alex, Ruppert, Elisabeth, Hesla, Per Egil, Poli, Francesca, Pizza, Fabio, Frauscher, Birgit, Jeong, Jong-Hyun, Lee, Sung-Pil, Strohl, Kingman P, Longstreth, William T, Kvale, Mark, Dobrovolna, Marie, Ohayon, Maurice M, Nepom, Gerald T, Wichmann, H-Erich, Rouleau, Guy A, Gieger, Christian, Levinson, Douglas F, Gejman, Pablo V, Meitinger, Thomas, Peppard, Paul, Young, Terry, Jennum, Poul, Steinman, Lawrence, Tokunaga, Katsushi, Kwok, Pui-Yan, Risch, Neil, Hallmayer, Joachim, Mignot, Emmanuel
Publicado 2010

Narcolepsy risk loci outline role of T cell autoimmunity and infectious triggers in narcolepsy

por Ollila, Hanna M., Sharon, Eilon, Lin, Ling, Sinnott-Armstrong, Nasa, Ambati, Aditya, Yogeshwar, Selina M., Hillary, Ryan P., Jolanki, Otto, Faraco, Juliette, Einen, Mali, Luo, Guo, Zhang, Jing, Han, Fang, Yan, Han, Dong, Xiao Song, Li, Jing, Zhang, Jun, Hong, Seung-Chul, Kim, Tae Won, Dauvilliers, Yves, Barateau, Lucie, Lammers, Gert Jan, Fronczek, Rolf, Mayer, Geert, Santamaria, Joan, Arnulf, Isabelle, Knudsen-Heier, Stine, Bredahl, May Kristin Lyamouri, Thorsby, Per Medbøe, Plazzi, Giuseppe, Pizza, Fabio, Moresco, Monica, Crowe, Catherine, Van den Eeden, Stephen K., Lecendreux, Michel, Bourgin, Patrice, Kanbayashi, Takashi, Martínez-Orozco, Francisco J., Peraita-Adrados, Rosa, Benetó, Antonio, Montplaisir, Jacques, Desautels, Alex, Huang, Yu-Shu, Jennum, Poul, Nevsimalova, Sona, Kemlink, David, Iranzo, Alex, Overeem, Sebastiaan, Wierzbicka, Aleksandra, Geisler, Peter, Sonka, Karel, Honda, Makoto, Högl, Birgit, Stefani, Ambra, Coelho, Fernando Morgadinho, Mantovani, Vilma, Feketeova, Eva, Wadelius, Mia, Eriksson, Niclas, Smedje, Hans, Hallberg, Pär, Hesla, Per Egil, Rye, David, Pelin, Zerrin, Ferini-Strambi, Luigi, Bassetti, Claudio L., Mathis, Johannes, Khatami, Ramin, Aran, Adi, Nampoothiri, Sheela, Olsson, Tomas, Kockum, Ingrid, Partinen, Markku, Perola, Markus, Kornum, Birgitte R., Rueger, Sina, Winkelmann, Juliane, Miyagawa, Taku, Toyoda, Hiromi, Khor, Seik-Soon, Shimada, Mihoko, Tokunaga, Katsushi, Rivas, Manuel, Pritchard, Jonathan K., Risch, Neil, Kutalik, Zoltan, O’Hara, Ruth, Hallmayer, Joachim, Ye, Chun Jimmie, Mignot, Emmanuel J.
Publicado 2023