Dysregulation of mTORC1/autophagy axis in senescence

por Carroll, Bernadette, Korolchuk, Viktor I.
Publicado 2017

Nutrient sensing, growth and senescence

por Carroll, Bernadette, Korolchuk, Viktor I.
Publicado 2018

The crosstalk of NAD, ROS and autophagy in cellular health and ageing

por Sedlackova, Lucia, Korolchuk, Viktor I.
Publicado 2020

mTORC1 and Nutrient Homeostasis: The Central Role of the Lysosome

por Rabanal-Ruiz, Yoana, Korolchuk, Viktor I.
Publicado 2018

The pROS of Autophagy in Neuronal Health

por Sedlackova, Lucia, Kelly, George, Korolchuk, Viktor I.
Publicado 2020

mTORC1 as the main gateway to autophagy

por Rabanal-Ruiz, Yoana, Otten, Elsje G., Korolchuk, Viktor I.
Publicado 2017

Mitochondria in Cell Senescence: Is Mitophagy the Weakest Link?

por Korolchuk, Viktor I., Miwa, Satomi, Carroll, Bernadette, von Zglinicki, Thomas
Publicado 2017

Oxidation of p62 as an evolutionary adaptation to promote autophagy in stress conditions

por Otten, Elsje G., Stefanatos, Rhoda, Carroll, Bernadette, Korolchuk, Viktor I.
Publicado 2018

Autophagy Inhibition Compromises Degradation of Ubiquitin-Proteasome Pathway Substrates

por Korolchuk, Viktor I., Mansilla, Alicia, Menzies, Fiona M., Rubinsztein, David C.
Publicado 2009

The mTORC1-autophagy pathway is a target for senescent cell elimination

por Kucheryavenko, Olena, Nelson, Glyn, von Zglinicki, Thomas, Korolchuk, Viktor I., Carroll, Bernadette
Publicado 2019

Increased telomerase improves motor function and alpha-synuclein pathology in a transgenic mouse model of Parkinson’s disease associated with enhanced autophagy

por Wan, Tengfei, Weir, Emma J., Johnson, Mary, Korolchuk, Viktor I., Saretzki, Gabriele C.
Publicado 2021

A Phagocytic Route for Uptake of Double-Stranded RNA in RNAi

por Rocha, João J. E., Korolchuk, Viktor I., Robinson, Iain M., O'Kane, Cahir J.
Publicado 2011

Lipids, lysosomes and mitochondria: insights into Lewy body formation from rare monogenic disorders

por Erskine, Daniel, Koss, David, Korolchuk, Viktor I., Outeiro, Tiago F., Attems, Johannes, McKeith, Ian
Publicado 2021

PI(5)P Regulates Autophagosome Biogenesis

por Vicinanza, Mariella, Korolchuk, Viktor I., Ashkenazi, Avraham, Puri, Claudia, Menzies, Fiona M., Clarke, Jonathan H., Rubinsztein, David C.
Publicado 2015

Analysis of autophagy deficiency and cytotoxicity in autophagy-deficient human embryonic stem cell-derived neurons

por Korsgen, Miriam E., Sun, Congxin, Seranova, Elena, Zatyka, Malgorzata, Astuti, Dewi, Kataura, Tetsushi, Barrett, Timothy, Korolchuk, Viktor I., Sarkar, Sovan
Publicado 2023

Dynamic Modelling of Pathways to Cellular Senescence Reveals Strategies for Targeted Interventions

por Dalle Pezze, Piero, Nelson, Glyn, Otten, Elsje G., Korolchuk, Viktor I., Kirkwood, Thomas B. L., von Zglinicki, Thomas, Shanley, Daryl P.
Publicado 2014

PCV2 replication promoted by oxidative stress is dependent on the regulation of autophagy on apoptosis

por Zhai, Nianhui, Liu, Kai, Li, Hu, Liu, Zixuan, Wang, Hong, Korolchuk, Viktor I., Carroll, Bernadette, Pan, Cuiling, Gan, Fang, Huang, Kehe, Chen, Xingxiang
Publicado 2019

Laforin, the most common protein mutated in Lafora disease, regulates autophagy

por Aguado, Carmen, Sarkar, Sovan, Korolchuk, Viktor I., Criado, Olga, Vernia, Santiago, Boya, Patricia, Sanz, Pascual, de Córdoba, Santiago Rodríguez, Knecht, Erwin, Rubinsztein, David C.
Publicado 2010

Genomic targets and selective inhibition of DNA methyltransferase isoforms

por Sae-Lee, Chanachai, Barrow, Timothy M., Colicino, Elena, Choi, Si Ho, Rabanal-Ruiz, Yoana, Green, Daniel, Korolchuk, Viktor I., Mathers, John C., Byun, Hyang-Min
Publicado 2022

Short senolytic or senostatic interventions rescue progression of radiation-induced frailty and premature ageing in mice

por Fielder, Edward, Wan, Tengfei, Alimohammadiha, Ghazaleh, Ishaq, Abbas, Low, Evon, Weigand, B Melanie, Kelly, George, Parker, Craig, Griffin, Brigid, Jurk, Diana, Korolchuk, Viktor I, von Zglinicki, Thomas, Miwa, Satomi
Publicado 2022