The revival of CpG oligonucleotide-based cancer immunotherapies

por Adamus, Tomasz, Kortylewski, Marcin
Publicado 2018

Push and release: TLR9 activation plus STAT3 blockade for systemic antitumor immunity

por Kortylewski, Marcin, Kuo, Ya-Huei
Publicado 2014

The dark side of Toll-like receptor signaling: TLR9 activation limits the efficacy cancer radiotherapy

por Kortylewski, Marcin, Pal, Sumanta K
Publicado 2014

Editorial: Roles of Tumor-Recruited Myeloid Cells in Immune Evasion in Cancer

por Kusmartsev, Sergei, Serafini, Paolo, Bharadwaj, Srinivas Nagaraj, Kortylewski, Marcin
Publicado 2021

STAT3 in Tumor-Associated Myeloid Cells: Multitasking to Disrupt Immunity

por Su, Yu-Lin, Banerjee, Shuvomoy, White, Seok Voon, Kortylewski, Marcin
Publicado 2018

IL-17 can promote tumor growth through an IL-6–Stat3 signaling pathway

por Wang, Lin, Yi, Tangsheng, Kortylewski, Marcin, Pardoll, Drew M., Zeng, Defu, Yu, Hua
Publicado 2009

Cell-selective oligonucleotide STAT3 inhibitor for immunotherapy of human acute myeloid leukemia

por Zhang, Qifang, Hossain, Sakib, Moreira, Dayson, Duttagupta, Priyanka, Zhao, Xingli, Swiderski, Piotr, Kortylewski, Marcin
Publicado 2015

Targeted TLR9-activation/STAT3-blocking abrogates immunosuppressive functions of myeloid-derived suppressor cells from late-stage prostate cancer patients

por Md Sakib Hossain, Dewan, Moreira, Dayson, Zhang, Qifang, Forman, Stephen J, Pal, Sumanta, Kortylewski, Marcin
Publicado 2014

Combined modality radiation therapy promotes tolerogenic myeloid cell populations and STAT3-related gene expression in head and neck cancer patients

por Sampath, Sagus, Won, Haejung, Massarelli, Erminia, Li, Min, Frankel, Paul, Vora, Nayana, Vora, Lalit, Maghami, Ellie, Kortylewski, Marcin
Publicado 2018

Novel Target Opportunities in Non-Metastatic Castrate Resistant Prostate Cancer

por Gleicher, Stephanie, Porter, Baylee A., Nath, Disharee, Li, Guanqun, Khanna, Rakesh, Goldberg, Hanan, Kortylewski, Marcin, Bratslavsky, Gennady, Kotula, Leszek
Publicado 2021

SNAIL is a key regulator of alveolar rhabdomyosarcoma tumor growth and differentiation through repression of MYF5 and MYOD function

por Skrzypek, Klaudia, Kusienicka, Anna, Trzyna, Elzbieta, Szewczyk, Barbara, Ulman, Aleksandra, Konieczny, Pawel, Adamus, Tomasz, Badyra, Bogna, Kortylewski, Marcin, Majka, Marcin
Publicado 2018

Reduced T-cell Numbers and Elevated Levels of Immunomodulatory Cytokines in Metastatic Prostate Cancer Patients De Novo Resistant to Abiraterone and/or Enzalutamide Therapy

por Pal, Sumanta K., Moreira, Dayson, Won, Haejung, White, Seok Woon, Duttagupta, Pryanka, Lucia, Marc, Jones, Jeremy, Hsu, JoAnn, Kortylewski, Marcin
Publicado 2019

Stat3-induced S1PR1 expression is critical for persistent Stat3 activation in tumors

por Lee, Heehyoung, Deng, Jiehui, Kujawski, Maciej, Yang, Chunmei, Liu, Yong, Herrmann, Andreas, Kortylewski, Marcin, Horne, David, Somlo, George, Forman, Stephen, Jove, Richard, Yu, Hua
Publicado 2010

Systemic delivery of TLR9-activating/STAT3-blocking oligonucleotides induces leukemia regression

por Zhang, Qifang, Md Sakib Hossain, Dewan, Nechaev, Sergey, Buettner, Ralf, Swiderski, Piotr, Jozwiak, Agnieszka, Forman, Stephen J, Bhatia, Ravi, Kuo, Ya-Huei, Kortylewski, Marcin
Publicado 2014

Cutting-edge advances in modeling the blood–brain barrier and tools for its reversible permeabilization for enhanced drug delivery into the brain

por Sharma, Amit, Fernandes, Diogo C., Reis, Rui L., Gołubczyk, Dominika, Neumann, Silke, Lukomska, Barbara, Janowski, Miroslaw, Kortylewski, Marcin, Walczak, Piotr, Oliveira, J. Miguel, Maciaczyk, Jarek
Publicado 2023

TLR9 signaling through NF-κB/RELA and STAT3 promotes tumor-propagating potential of prostate cancer cells

por Moreira, Dayson, Zhang, Qifang, Hossain, Dewan Md S., Nechaev, Sergey, Li, Haiqing, Kowolik, Claudia M., D'Apuzzo, Massimo, Forman, Stephen, Jones, Jeremy, Pal, Sumanta K., Kortylewski, Marcin
Publicado 2015

Biophysical Characterization of the Leukemic Bone Marrow Vasculature Reveals Benefits of Neoadjuvant Low-Dose Radiation Therapy

por Brooks, Jamison, Kumar, Bijender, Zuro, Darren M., Raybuck, Jonathan D., Madabushi, Srideshikan Sargur, Vishwasrao, Paresh, Parra, Liliana Echavarria, Kortylewski, Marcin, Armstrong, Brian, Froelich, Jerry, Hui, Susanta K.
Publicado 2020

Circulating cytokines associated with clinical response to systemic therapy in metastatic renal cell carcinoma

por Chehrazi-Raffle, Alexander, Meza, Luis, Alcantara, Marice, Dizman, Nazli, Bergerot, Paulo, Salgia, Nicholas, Hsu, JoAnn, Ruel, Nora, Salgia, Sabrina, Malhotra, Jasnoor, Karczewska, Ewa, Kortylewski, Marcin, Pal, Sumanta
Publicado 2021

Glioma-targeted delivery of exosome-encapsulated antisense oligonucleotides using neural stem cells

por Adamus, Tomasz, Hung, Chia-Yang, Yu, Chunsong, Kang, Elaine, Hammad, Mohamed, Flores, Linda, Nechaev, Sergey, Zhang, Qifang, Gonzaga, Joanna Marie, Muthaiyah, Kokilah, Swiderski, Piotr, Aboody, Karen S., Kortylewski, Marcin
Publicado 2021

B Cell Lymphoma Immunotherapy Using TLR9-Targeted Oligonucleotide STAT3 Inhibitors

por Zhao, Xingli, Zhang, Zhuoran, Moreira, Dayson, Su, Yu-Lin, Won, Haejung, Adamus, Tomasz, Dong, Zhenyuan, Liang, Yong, Yin, Hongwei H., Swiderski, Piotr, Pillai, Raju K., Kwak, Larry, Forman, Stephen, Kortylewski, Marcin
Publicado 2018