Computational analyses for cancer biology based on exhaustive experimental backgrounds

por Koseki, Jun, Konno, Masamitsu, Ishii, Hideshi
Publicado 2019

Bayesian statistical method for detecting structural and topological diversity in polymorphic proteins

por Hayashi, Shuto, Koseki, Jun, Shimamura, Teppei
Publicado 2022

Topological data analysis of protein structure and inter/intra-molecular interaction changes attributable to amino acid mutations

por Koseki, Jun, Hayashi, Shuto, Kojima, Yasuhiro, Hirose, Haruka, Shimamura, Teppei
Publicado 2023

Direct Analysis of Incorporation of an Anticancer Drug into DNA at Single-Molecule Resolution

por Ohshiro, Takahito, Komoto, Yuuki, Konno, Masamitsu, Koseki, Jun, Asai, Ayumu, Ishii, Hideshi, Taniguchi, Masateru
Publicado 2019

UVB-Induced Skin Autoinflammation Due to Nlrp1b Mutation and Its Inhibition by Anti-IL-1β Antibody

por Murase, Yuya, Takeichi, Takuya, Koseki, Jun, Miyasaka, Yuki, Muro, Yoshinao, Ohno, Tamio, Shimamura, Teppei, Akiyama, Masashi
Publicado 2022

A Trans-omics Mathematical Analysis Reveals Novel Functions of the Ornithine Metabolic Pathway in Cancer Stem Cells

por Koseki, Jun, Matsui, Hidetoshi, Konno, Masamitsu, Nishida, Naohiro, Kawamoto, Koichi, Kano, Yoshihiro, Mori, Masaki, Doki, Yuichiro, Ishii, Hideshi
Publicado 2016

MicroRNA profiles involved in trifluridine resistance

por Tsunekuni, Kenta, Konno, Masamitsu, Asai, Ayumu, Koseki, Jun, Kobunai, Takashi, Takechi, Teiji, Doki, Yuichiro, Mori, Masaki, Ishii, Hideshi
Publicado 2017

Drug discovery of anticancer drugs targeting methylenetetrahydrofolate dehydrogenase 2

por Asai, Ayumu, Koseki, Jun, Konno, Masamitsu, Nishimura, Tatsunori, Gotoh, Noriko, Satoh, Taroh, Doki, Yuichiro, Mori, Masaki, Ishii, Hideshi
Publicado 2018

Theoretical analyses and experimental validation of the effects caused by the fluorinated substituent modification of DNA

por Koseki, Jun, Konno, Masamitsu, Asai, Ayumu, Horie, Naohiro, Tsunekuni, Kenta, Kawamoto, Koichi, Obika, Satoshi, Doki, Yuichiro, Mori, Masaki, Ishii, Hideshi
Publicado 2020

Mitochondrial pyruvate carrier 1 expression controls cancer epithelial‐mesenchymal transition and radioresistance

por Takaoka, Yuji, Konno, Masamitsu, Koseki, Jun, Colvin, Hugh, Asai, Ayumu, Tamari, Keisuke, Satoh, Taroh, Mori, Masaki, Doki, Yuichiro, Ogawa, Kazuhiko, Ishii, Hideshi
Publicado 2019

CD44/CD133-Positive Colorectal Cancer Stem Cells are Sensitive to Trifluridine Exposure

por Tsunekuni, Kenta, Konno, Masamitsu, Haraguchi, Naotsugu, Koseki, Jun, Asai, Ayumu, Matsuoka, Kazuaki, Kobunai, Takashi, Takechi, Teiji, Doki, Yuichiro, Mori, Masaki, Ishii, Hideshi
Publicado 2019

Susceptibility of pancreatic cancer stem cells to reprogramming

por Noguchi, Kozo, Eguchi, Hidetoshi, Konno, Masamitsu, Kawamoto, Koichi, Nishida, Naohiro, Koseki, Jun, Wada, Hiroshi, Marubashi, Shigeru, Nagano, Hiroaki, Doki, Yuichiro, Mori, Masaki, Ishii, Hideshi
Publicado 2015

Enzymes of the one-carbon folate metabolism as anticancer targets predicted by survival rate analysis

por Koseki, Jun, Konno, Masamitsu, Asai, Ayumu, Colvin, Hugh, Kawamoto, Koichi, Nishida, Naohiro, Sakai, Daisuke, Kudo, Toshihiro, Satoh, Taroh, Doki, Yuichiro, Mori, Masaki, Ishii, Hideshi
Publicado 2018

Low expression of the GOPC is a poor prognostic marker in colorectal cancer

por Ohara, Nobuyoshi, Haraguchi, Naotsugu, Koseki, Jun, Nishizawa, Yujiro, Kawai, Kenji, Takahashi, Hidekazu, Nishimura, Junichi, Hata, Taishi, Mizushima, Tsunekazu, Yamamoto, Hirofumi, Ishii, Hideshi, Doki, Yuichiro, Mori, Masaki
Publicado 2017

Computational trans-omics approach characterised methylomic and transcriptomic involvements and identified novel therapeutic targets for chemoresistance in gastrointestinal cancer...

por Konno, Masamitsu, Matsui, Hidetoshi, Koseki, Jun, Asai, Ayumu, Kano, Yoshihiro, Kawamoto, Koichi, Nishida, Naohiro, Sakai, Daisuke, Kudo, Toshihiro, Satoh, Taroh, Doki, Yuichiro, Mori, Masaki, Ishii, Hideshi
Publicado 2018

Combined evaluation of hexokinase 2 and phosphorylated pyruvate dehydrogenase-E1α in invasive front lesions of colorectal tumors predicts cancer metabolism and patient prognosis

por Hamabe, Atsushi, Yamamoto, Hirofumi, Konno, Masamitsu, Uemura, Mamoru, Nishimura, Junichi, Hata, Taishi, Takemasa, Ichiro, Mizushima, Tsunekazu, Nishida, Naohiro, Kawamoto, Koichi, Koseki, Jun, Doki, Yuichiro, Mori, Masaki, Ishii, Hideshi
Publicado 2014

Embryonic MicroRNA-369 Controls Metabolic Splicing Factors and Urges Cellular Reprograming

por Konno, Masamitsu, Koseki, Jun, Kawamoto, Koichi, Nishida, Naohiro, Matsui, Hidetoshi, Dewi, Dyah Laksmi, Ozaki, Miyuki, Noguchi, Yuko, Mimori, Koshi, Gotoh, Noriko, Tanuma, Nobuhiro, Shima, Hiroshi, Doki, Yuichiro, Mori, Masaki, Ishii, Hideshi
Publicado 2015

Oncometabolite D-2-Hydroxyglurate Directly Induces Epithelial-Mesenchymal Transition and is Associated with Distant Metastasis in Colorectal Cancer

por Colvin, Hugh, Nishida, Naohiro, Konno, Masamitsu, Haraguchi, Naotsugu, Takahashi, Hidekazu, Nishimura, Junichi, Hata, Taishi, Kawamoto, Koichi, Asai, Ayumu, Tsunekuni, Kenta, Koseki, Jun, Mizushima, Tsunekazu, Satoh, Taroh, Doki, Yuichiro, Mori, Masaki, Ishii, Hideshi
Publicado 2016

Polyamine flux suppresses histone lysine demethylases and enhances ID1 expression in cancer stem cells

por Tamari, Keisuke, Konno, Masamitsu, Asai, Ayumu, Koseki, Jun, Hayashi, Kazuhiko, Kawamoto, Koichi, Murai, Noriyuki, Matsufuji, Senya, Isohashi, Fumiaki, Satoh, Taroh, Goto, Noriko, Tanaka, Shinji, Doki, Yuichiro, Mori, Masaki, Ogawa, Kazuhiko, Ishii, Hideshi
Publicado 2018

Pyruvate kinase M2, but not M1, allele maintains immature metabolic states of murine embryonic stem cells

por Konno, Masamitsu, Ishii, Hideshi, Koseki, Jun, Tanuma, Nobuhiro, Nishida, Naohiro, Kawamoto, Koichi, Nishimura, Tatsunori, Nakata, Asuka, Matsui, Hidetoshi, Noguchi, Kozou, Ozaki, Miyuki, Noguchi, Yuko, Shima, Hiroshi, Gotoh, Noriko, Nagano, Hiroaki, Doki, Yuichiro, Mori, Masaki
Publicado 2015