Th1 cytokines in conjunction with pharmacological Akt inhibition potentiate apoptosis of breast cancer cells in vitro and suppress tumor growth in vivo

por Showalter, Loral, Czerniecki, Brian J., Koski, Gary K.
Publicado 2020

LEAPS Vaccine Incorporating HER-2/neu Epitope Elicits Protection That Prevents and Limits Tumor Growth and Spread of Breast Cancer in a Mouse Model

por Rosenthal, Ken S., Stone, Sarah, Koski, Gary, Zimmerman, Daniel H.
Publicado 2017

T-helper 1-type cytokines induce apoptosis and loss of HER-family oncodriver expression in murine and human breast cancer cells

por Namjoshi, Prachi, Showalter, Lori, Czerniecki, Brian J., Koski, Gary K.
Publicado 2019

Murine Dendritic Cells Grown in Serum-Free Culture Show Potent Therapeutic Activity when Loaded with Novel Th Epitopes in an Orthotopic Model of HER2(pos) Breast Cancer

por Showalter, Loral E., Czerniecki, Brian J., Kodumudi, Krithika, Koski, Gary K.
Publicado 2021

Sunitinib Combined with Th1 Cytokines Potentiates Apoptosis in Human Breast Cancer Cells and Suppresses Tumor Growth in a Murine Model of HER-2(pos) Breast Cancer

por Ghimirey, Nirmala, Steele, Chase, Czerniecki, Brian J., Koski, Gary K., Showalter, Loral E.
Publicado 2021

Th1 cytokines sensitize HER-expressing breast cancer cells to lapatinib

por Showalter, Loral E., Oechsle, Crystal, Ghimirey, Nirmala, Steele, Chase, Czerniecki, Brian J., Koski, Gary K.
Publicado 2019

Statin Drugs Plus Th1 Cytokines Potentiate Apoptosis and Ras Delocalization in Human Breast Cancer Lines and Combine with Dendritic Cell-Based Immunotherapy to Suppress Tumor Growt...

por Oechsle, Crystal M., Showalter, Loral E., Novak, Colleen M., Czerniecki, Brain J., Koski, Gary K.
Publicado 2020

Differentiation and Regulation of T(H) Cells: A Balancing Act for Cancer Immunotherapy

por Basu, Amrita, Ramamoorthi, Ganesan, Albert, Gabriella, Gallen, Corey, Beyer, Amber, Snyder, Colin, Koski, Gary, Disis, Mary L., Czerniecki, Brian J., Kodumudi, Krithika
Publicado 2021

Extracellular ATP and Toll-Like Receptor 2 Agonists Trigger in Human Monocytes an Activation Program That Favors T Helper 17

por Paustian, Christopher, Taylor, Patricia, Johnson, Terrence, Xu, Min, Ramirez, Nancy, Rosenthal, Kenneth S., Shu, Suyu, Cohen, Peter A., Czerniecki, Brian J., Koski, Gary K.
Publicado 2013

Intratumoral delivery of dendritic cells plus anti-HER2 therapy triggers both robust systemic antitumor immunity and complete regression in HER2 mammary carcinoma

por Ramamoorthi, Ganesan, Kodumudi, Krithika, Snyder, Colin, Grover, Payal, Zhang, Hongtao, Greene, Mark I, Basu, Amrita, Gallen, Corey, Wiener, Doris, Costa, Ricardo L B, Han, Hyo S, Koski, Gary, Czerniecki, Brian J
Publicado 2022

Th1 cytokine interferon gamma improves response in HER2 breast cancer by modulating the ubiquitin proteasomal pathway

por Jia, Yongsheng, Kodumudi, Krithika N., Ramamoorthi, Ganesan, Basu, Amrita, Snyder, Colin, Wiener, Doris, Pilon-Thomas, Shari, Grover, Payal, Zhang, Hongtao, Greene, Mark I., Mo, Qianxing, Tong, Zhongsheng, Chen, Yong-Zi, Costa, Ricardo L.B., Han, Hyo, Lee, Catherine, Soliman, Hatem, Conejo-Garcia, Jose R., Koski, Gary, Czerniecki, Brian J.
Publicado 2021

Identification of Immunogenic MHC Class II Human HER3 Peptides that Mediate Anti-HER3 CD4(+) Th1 Responses and Potential Use as a Cancer Vaccine

por Basu, Amrita, Albert, Gabriella K., Awshah, Sabrina, Datta, Jashodeep, Kodumudi, Krithika N., Gallen, Corey, Beyer, Amber, Smalley, Keiran S.M., Rodriguez, Paulo C., Duckett, Derek R., Forsyth, Peter A., Soyano, Aixa, Koski, Gary K., Lima Barros Costa, Ricardo, Han, Heather, Soliman, Hatem, Lee, Marie Catherine, Kalinski, Pawel, Czerniecki, Brian J.
Publicado 2022