A Microphysiological System for Studying Nonalcoholic Steatohepatitis

por Kostrzewski, Tomasz, Maraver, Paloma, Ouro‐Gnao, Larissa, Levi, Ana, Snow, Sophie, Miedzik, Alina, Rombouts, Krista, Hughes, David
Publicado 2019

Three-dimensional perfused human in vitro model of non-alcoholic fatty liver disease

por Kostrzewski, Tomasz, Cornforth, Terri, Snow, Sophie A, Ouro-Gnao, Larissa, Rowe, Cliff, Large, Emma M, Hughes, David J
Publicado 2017

The transcription factor E4bp4/Nfil3 controls commitment to the NK lineage and directly regulates Eomes and Id2 expression

por Male, Victoria, Nisoli, Ilaria, Kostrzewski, Tomasz, Allan, David S.J., Carlyle, James R., Lord, Graham M., Wack, Andreas, Brady, Hugh J.M.
Publicado 2014

Characterizing the reproducibility in using a liver microphysiological system for assaying drug toxicity, metabolism, and accumulation

por Rubiano, Andrés, Indapurkar, Amruta, Yokosawa, Ryosuke, Miedzik, Alina, Rosenzweig, Barry, Arefin, Ayesha, Moulin, Chloe M., Dame, Keri, Hartman, Neil, Volpe, Donna A., Matta, Murali K., Hughes, David J., Strauss, David G., Kostrzewski, Tomasz, Ribeiro, Alexandre J. S.
Publicado 2021

Modelling human liver fibrosis in the context of non-alcoholic steatohepatitis using a microphysiological system

por Kostrzewski, Tomasz, Snow, Sophie, Battle, Anya Lindström, Peel, Samantha, Ahmad, Zahida, Basak, Jayati, Surakala, Manasa, Bornot, Aurelie, Lindgren, Julia, Ryaboshapkina, Maria, Clausen, Maryam, Lindén, Daniel, Maass, Christian, Young, Lucy May, Corrigan, Adam, Ewart, Lorna, Hughes, David
Publicado 2021

A microfluidic system that replicates pharmacokinetic (PK) profiles in vitro improves prediction of in vivo efficacy in preclinical models

por Singh, Dharaminder, Deosarkar, Sudhir P., Cadogan, Elaine, Flemington, Vikki, Bray, Alysha, Zhang, Jingwen, Reiserer, Ronald S., Schaffer, David K., Gerken, Gregory B., Britt, Clayton M., Werner, Erik M., Gibbons, Francis D., Kostrzewski, Tomasz, Chambers, Christopher E., Davies, Emma J., Montoya, Antonio Ramos, Fok, Jacqueline H. L., Hughes, David, Fabre, Kristin, Wagoner, Matthew P., Wikswo, John P., Scott, Clay W.
Publicado 2022