Nanog-Independent Reprogramming to iPSCs with Canonical Factors

por Carter, Ava C., Davis-Dusenbery, Brandi N., Koszka, Kathryn, Ichida, Justin K., Eggan, Kevin
Publicado 2014

The mouse C9ORF72 ortholog is enriched in neurons known to degenerate in ALS and FTD

por Suzuki, Naoki, Maroof, Asif, Merkle, Florian T, Koszka, Kathryn, Intoh, Atsushi, Armstrong, Ian, Moccia, Rob, Davis-Dusenbery, Brandi N, Eggan, Kevin
Publicado 2013

Use of CRISPR/Cas9-mediated disruption of CNS cell type genes to profile transduction of AAV by neonatal intracerebroventricular delivery in mice

por Torregrosa, Tess, Lehman, Sydney, Hana, Sam, Marsh, Galina, Xu, Shanqin, Koszka, Kathryn, Mastrangelo, Nicole, McCampbell, Alexander, Henderson, Christopher E., Lo, Shih-Ching
Publicado 2021

Highly efficient neuronal gene knockout in vivo by CRISPR-Cas9 via neonatal intracerebroventricular injection of AAV in mice

por Hana, Sam, Peterson, Michael, McLaughlin, Helen, Marshall, Eric, Fabian, Attila J., McKissick, Olivia, Koszka, Kathryn, Marsh, Galina, Craft, Michael, Xu, Shanqin, Sorets, Alexander, Torregrosa, Tess, Sun, Chao, Henderson, Chris E., Lo, Shih-Ching
Publicado 2021

Efficacy and safety of a SOD1-targeting artificial miRNA delivered by AAV9 in mice are impacted by miRNA scaffold selection

por Chen, Shukkwan K., Hawley, Zachary C.E., Zavodszky, Maria I., Hana, Sam, Ferretti, Daniel, Grubor, Branka, Hawes, Michael, Xu, Shanqin, Hamann, Stefan, Marsh, Galina, Cullen, Patrick, Challa, Ravi, Carlile, Thomas M., Zhang, Hang, Lee, Wan-Hung, Peralta, Andrea, Clarner, Pete, Wei, Cong, Koszka, Kathryn, Gao, Feng, Lo, Shih-Ching
Publicado 2023

In vivo genome editing using novel AAV-PHP variants rescues motor function deficits and extends survival in a SOD1-ALS mouse model

por Chen, Yi A., Kankel, Mark W., Hana, Sam, Lau, Shukkwan Kelly, Zavodszky, Maria I., McKissick, Olivia, Mastrangelo, Nicole, Dion, Jessica, Wang, Bin, Ferretti, Daniel, Koske, David, Lehman, Sydney, Koszka, Kathryn, McLaughlin, Helen, Liu, Mei, Marshall, Eric, Fabian, Attila J., Cullen, Patrick, Marsh, Galina, Hamann, Stefan, Craft, Michael, Sebalusky, Jennifer, Arnold, H. Moore, Driscoll, Rachelle, Sheehy, Adam, Luo, Yi, Manca, Sonia, Carlile, Thomas, Sun, Chao, Sigrist, Kirsten, McCampbell, Alexander, Henderson, Christopher E., Lo, Shih-Ching
Publicado 2022