Regulatory and coding genome regions are enriched for trait associated variants in dairy and beef cattle

por Koufariotis, Lambros, Chen, Yi-Ping Phoebe, Bolormaa, Sunduimijid, Hayes, Ben J
Publicado 2014

Variance explained by whole genome sequence variants in coding and regulatory genome annotations for six dairy traits

por Koufariotis, Lambros T., Chen, Yi-Ping Phoebe, Stothard, Paul, Hayes, Ben J.
Publicado 2018

A catalogue of novel bovine long noncoding RNA across 18 tissues

por Koufariotis, Lambros T., Chen, Yi-Ping Phoebe, Chamberlain, Amanda, Vander Jagt, Christy, Hayes, Ben J.
Publicado 2015

Efficient detection and monitoring of pediatric brain malignancies with liquid biopsy based on patient-specific somatic mutation screening

por Kojic, Marija, Maybury, Mellissa K, Waddell, Nicola, Koufariotis, Lambros T, Addala, Venkateswar, Millar, Amanda, Wood, Scott, Pearson, John V, Hansford, Jordan R, Hassall, Tim, Wainwright, Brandon J
Publicado 2023

Verifying explainability of a deep learning tissue classifier trained on RNA-seq data

por Yap, Melvyn, Johnston, Rebecca L., Foley, Helena, MacDonald, Samual, Kondrashova, Olga, Tran, Khoa A., Nones, Katia, Koufariotis, Lambros T., Bean, Cameron, Pearson, John V., Trzaskowski, Maciej, Waddell, Nicola
Publicado 2021

Generalising uncertainty improves accuracy and safety of deep learning analytics applied to oncology

por MacDonald, Samual, Foley, Helena, Yap, Melvyn, Johnston, Rebecca L., Steven, Kaiah, Koufariotis, Lambros T., Sharma, Sowmya, Wood, Scott, Addala, Venkateswar, Pearson, John V., Roosta, Fred, Waddell, Nicola, Kondrashova, Olga, Trzaskowski, Maciej
Publicado 2023

The oesophageal adenocarcinoma tumour immune microenvironment dictates outcomes with different modalities of neoadjuvant therapy – results from the AGITG DOCTOR trial and the cance...

por Lonie, James M., Brosda, Sandra, Bonazzi, Vanessa F., Aoude, Lauren G., Patel, Kalpana, Brown, Ian, Sharma, Sowmya, Lampe, Guy, Addala, Venkateswar, Koufariotis, Lambros T., Wood, Scott, Waddell, Nicola, Dolcetti, Riccardo, Barbour, Andrew P.
Publicado 2023

Donor bone marrow–derived macrophage MHC II drives neuroinflammation and altered behavior during chronic GVHD in mice

por Adams, Rachael C., Carter-Cusack, Dylan, Shaikh, Samreen N., Llanes, Genesis T., Johnston, Rebecca L., Quaife-Ryan, Gregory, Boyle, Glen, Koufariotis, Lambros T., Möller, Andreas, Blazar, Bruce R., Vukovic, Jana, MacDonald, Kelli P. A.
Publicado 2022

Alterations in signaling pathways that accompany spontaneous transition to malignancy in a mouse model of BRAF mutant microsatellite stable colorectal cancer

por Kane, Alexandra M., Fennell, Lochlan J., Liu, Cheng, Borowsky, Jennifer, McKeone, Diane M., Bond, Catherine E., Kazakoff, Stephen, Patch, Ann-Marie, Koufariotis, Lambros T., Pearson, John, Waddell, Nicola, Leggett, Barbara A., Whitehall, Vicki L.J.
Publicado 2020

Performance of tumour microenvironment deconvolution methods in breast cancer using single-cell simulated bulk mixtures

por Tran, Khoa A., Addala, Venkateswar, Johnston, Rebecca L., Lovell, David, Bradley, Andrew, Koufariotis, Lambros T., Wood, Scott, Wu, Sunny Z., Roden, Daniel, Al-Eryani, Ghamdan, Swarbrick, Alexander, Williams, Elizabeth D., Pearson, John V., Kondrashova, Olga, Waddell, Nicola
Publicado 2023

Pathogenic germline variants are associated with poor survival in stage III/IV melanoma patients

por Aoude, Lauren G., Bonazzi, Vanessa F., Brosda, Sandra, Patel, Kalpana, Koufariotis, Lambros T., Oey, Harald, Nones, Katia, Wood, Scott, Pearson, John V., Lonie, James M., Arneil, Melissa, Atkinson, Victoria, Smithers, B. Mark, Waddell, Nicola, Barbour, Andrew P.
Publicado 2020

Increased amphiregulin expression by CD4(+) T cells from individuals with asymptomatic Leishmania donovani infection

por Singh, Siddharth Sankar, Chauhan, Shashi Bhushan, Ng, Susanna SS, Corvino, Dillon, de Labastida Rivera, Fabian, Engel, Jessica A, Waddell, Nic, Mukhopadhay, Pamela, Johnston, Rebecca L, Koufariotis, Lambros T, Nylen, Susanne, Prakash Singh, Om, Engwerda, Christian R, Kumar, Rajiv, Sundar, Shyam
Publicado 2022

Targeting novel LSD1-dependent ACE2 demethylation domains inhibits SARS-CoV-2 replication

por Tu, Wen Juan, McCuaig, Robert D., Melino, Michelle, Rawle, Daniel J., Le, Thuy T., Yan, Kexin, Suhrbier, Andreas, Johnston, Rebecca L., Koufariotis, Lambros T., Waddell, Nicola, Cross, Emily M., Tsimbalyuk, Sofiya, Bain, Amanda, Ahern, Elizabeth, Collinson, Natasha, Phipps, Simon, Forwood, Jade K., Seddiki, Nabila, Rao, Sudha
Publicado 2021

Author Correction: Targeting novel LSD1-dependent ACE2 demethylation domains inhibits SARS-CoV-2 replication

por Tu, Wen Juan, McCuaig, Robert D., Melino, Michelle, Rawle, Daniel J., Le, Thuy T., Yan, Kexin, Suhrbier, Andreas, Johnston, Rebecca L., Koufariotis, Lambros T., Waddell, Nicola, Cross, Emily M., Tsimbalyuk, Sofiya, Bain, Amanda, Ahern, Elizabeth, Collinson, Natasha, Phipps, Simon, Forwood, Jade K., Seddiki, Nabila, Rao, Sudha
Publicado 2021

Patient-derived xenograft models capture genomic heterogeneity in endometrial cancer

por Bonazzi, Vanessa F., Kondrashova, Olga, Smith, Deborah, Nones, Katia, Sengal, Asmerom T., Ju, Robert, Packer, Leisl M., Koufariotis, Lambros T., Kazakoff, Stephen H., Davidson, Aimee L., Ramarao-Milne, Priya, Lakis, Vanessa, Newell, Felicity, Rogers, Rebecca, Davies, Claire, Nicklin, James, Garrett, Andrea, Chetty, Naven, Perrin, Lewis, Pearson, John V., Patch, Ann-Marie, Waddell, Nicola, Pollock, Pamela M.
Publicado 2022

Non-coding RNAs underlie genetic predisposition to breast cancer

por Moradi Marjaneh, Mahdi, Beesley, Jonathan, O’Mara, Tracy A., Mukhopadhyay, Pamela, Koufariotis, Lambros T., Kazakoff, Stephen, Hussein, Nehal, Fachal, Laura, Bartonicek, Nenad, Hillman, Kristine M., Kaufmann, Susanne, Sivakumaran, Haran, Smart, Chanel E., McCart Reed, Amy E., Ferguson, Kaltin, Saunus, Jodi M., Lakhani, Sunil R., Barnes, Daniel R., Antoniou, Antonis C., Dinger, Marcel E., Waddell, Nicola, Easton, Douglas F., Dunning, Alison M., Chenevix-Trench, Georgia, Edwards, Stacey L., French, Juliet D.
Publicado 2020

Comprehensive genomic and tumour immune profiling reveals potential therapeutic targets in malignant pleural mesothelioma

por Creaney, Jenette, Patch, Ann-Marie, Addala, Venkateswar, Sneddon, Sophie A., Nones, Katia, Dick, Ian M., Lee, Y. C. Gary, Newell, Felicity, Rouse, Ebony J., Naeini, Marjan M., Kondrashova, Olga, Lakis, Vanessa, Nakas, Apostolos, Waller, David, Sharkey, Annabel, Mukhopadhyay, Pamela, Kazakoff, Stephen H., Koufariotis, Lambros T., Davidson, Aimee L., Ramarao-Milne, Priya, Holmes, Oliver, Xu, Qinying, Leonard, Conrad, Wood, Scott, Grimmond, Sean M., Bueno, Raphael, Fennell, Dean A., Pearson, John V., Robinson, Bruce W., Waddell, Nicola
Publicado 2022

IL-10-producing Th1 cells possess a distinct molecular signature in malaria

por Edwards, Chelsea L., Ng, Susanna S., de Labastida Rivera, Fabian, Corvino, Dillon, Engel, Jessica A., Montes de Oca, Marcela, Bukali, Luzia, Frame, Teija C.M., Bunn, Patrick T., Chauhan, Shashi Bhushan, Singh, Siddharth Sankar, Wang, Yulin, Na, Jinrui, Amante, Fiona H., Loughland, Jessica R., Soon, Megan S.F., Waddell, Nicola, Mukhopadhay, Pamela, Koufariotis, Lambros T., Johnston, Rebecca L., Lee, Jason S., Kuns, Rachel, Zhang, Ping, Boyle, Michelle J., Hill, Geoffrey R., McCarthy, James S., Kumar, Rajiv, Engwerda, Christian R.
Publicado 2023

IL-10–producing Th1 cells possess a distinct molecular signature in malaria

por Edwards, Chelsea L., Ng, Susanna S., de Labastida Rivera, Fabian, Corvino, Dillon, Engel, Jessica A., Montes de Oca, Marcela, Bukali, Luzia, Frame, Teija C.M., Bunn, Patrick T., Chauhan, Shashi Bhushan, Singh, Siddharth Sankar, Wang, Yulin, Na, Jinrui, Amante, Fiona H., Loughland, Jessica R., Soon, Megan S.F., Waddell, Nicola, Mukhopadhay, Pamela, Koufariotis, Lambros T., Johnston, Rebecca L., Lee, Jason S., Kuns, Rachel, Zhang, Ping, Boyle, Michelle J., Hill, Geoffrey R., McCarthy, James S., Kumar, Rajiv, Engwerda, Christian R.
Publicado 2023

DNA methylation patterns identify subgroups of pancreatic neuroendocrine tumors with clinical association

por Lakis, Vanessa, Lawlor, Rita T., Newell, Felicity, Patch, Ann-Marie, Mafficini, Andrea, Sadanandam, Anguraj, Koufariotis, Lambros T., Johnston, Rebecca L., Leonard, Conrad, Wood, Scott, Rusev, Borislav, Corbo, Vincenzo, Luchini, Claudio, Cingarlini, Sara, Landoni, Luca, Salvia, Roberto, Milella, Michele, Chang, David, Bailey, Peter, Jamieson, Nigel B., Duthie, Fraser, Gingras, Marie-Claude, Muzny, Donna M., Wheeler, David A., Gibbs, Richard A., Milione, Massimo, Pederzoli, Paolo, Samra, Jaswinder S., Gill, Anthony J., Johns, Amber L., Pearson, John V., Biankin, Andrew V., Grimmond, Sean M., Waddell, Nicola, Nones, Katia, Scarpa, Aldo
Publicado 2021