Looking for therapeutic antibodies in next-generation sequencing repositories

por Krawczyk, Konrad, Raybould, Matthew I. J., Kovaltsuk, Aleksandr, Deane, Charlotte M.
Publicado 2019

How B-Cell Receptor Repertoire Sequencing Can Be Enriched with Structural Antibody Data

por Kovaltsuk, Aleksandr, Krawczyk, Konrad, Galson, Jacob D., Kelly, Dominic F., Deane, Charlotte M., Trück, Johannes
Publicado 2017

Different B cell subpopulations show distinct patterns in their IgH repertoire metrics

por Ghraichy, Marie, von Niederhäusern, Valentin, Kovaltsuk, Aleksandr, Galson, Jacob D, Deane, Charlotte M, Trück, Johannes
Publicado 2021

Public Baseline and shared response structures support the theory of antibody repertoire functional commonality

por Raybould, Matthew I. J., Marks, Claire, Kovaltsuk, Aleksandr, Lewis, Alan P., Shi, Jiye, Deane, Charlotte M.
Publicado 2021

AbDiver: a tool to explore the natural antibody landscape to aid therapeutic design

por Młokosiewicz, Jakub, Deszyński, Piotr, Wilman, Wiktoria, Jaszczyszyn, Igor, Ganesan, Rajkumar, Kovaltsuk, Aleksandr, Leem, Jinwoo, Galson, Jacob D, Krawczyk, Konrad
Publicado 2022

Structural diversity of B-cell receptor repertoires along the B-cell differentiation axis in humans and mice

por Kovaltsuk, Aleksandr, Raybould, Matthew I. J., Wong, Wing Ki, Marks, Claire, Kelm, Sebastian, Snowden, James, Trück, Johannes, Deane, Charlotte M.
Publicado 2020

Maturation of the Human Immunoglobulin Heavy Chain Repertoire With Age

por Ghraichy, Marie, Galson, Jacob D., Kovaltsuk, Aleksandr, von Niederhäusern, Valentin, Pachlopnik Schmid, Jana, Recher, Mike, Jauch, Annaïse J., Miho, Enkelejda, Kelly, Dominic F., Deane, Charlotte M., Trück, Johannes
Publicado 2020

Characterisation of the immune repertoire of a humanised transgenic mouse through immunophenotyping and high-throughput sequencing

por Richardson, Eve, Binter, Špela, Kosmac, Miha, Ghraichy, Marie, von Niederhäusern, Valentin, Kovaltsuk, Aleksandr, Galson, Jacob D, Trück, Johannes, Kelly, Dominic F, Deane, Charlotte M, Kellam, Paul, Watson, Simon J
Publicado 2023

Structurally Mapping Antibody Repertoires

por Krawczyk, Konrad, Kelm, Sebastian, Kovaltsuk, Aleksandr, Galson, Jacob D., Kelly, Dominic, Trück, Johannes, Regep, Cristian, Leem, Jinwoo, Wong, Wing K., Nowak, Jaroslaw, Snowden, James, Wright, Michael, Starkie, Laura, Scott-Tucker, Anthony, Shi, Jiye, Deane, Charlotte M.
Publicado 2018

Deep Sequencing of B Cell Receptor Repertoires From COVID-19 Patients Reveals Strong Convergent Immune Signatures

por Galson, Jacob D., Schaetzle, Sebastian, Bashford-Rogers, Rachael J. M., Raybould, Matthew I. J., Kovaltsuk, Aleksandr, Kilpatrick, Gavin J., Minter, Ralph, Finch, Donna K., Dias, Jorge, James, Louisa K., Thomas, Gavin, Lee, Wing-Yiu Jason, Betley, Jason, Cavlan, Olivia, Leech, Alex, Deane, Charlotte M., Seoane, Joan, Caldas, Carlos, Pennington, Daniel J., Pfeffer, Paul, Osbourn, Jane
Publicado 2020